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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0014]' for entry matching: P82471

World-2DPAGE Repository (0014):  P82471


General information about the entry
View entry in simple text format
Entry nameGNAQ_RAT
Primary accession numberP82471
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Guanine nucleotide-binding protein G(q) subunit alpha; AltName: Full=Guanine nucleotide-binding protein alpha-q;.
Gene nameName=Gnaq
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=5.64; Mw=42000  [identification data]
pI=5.40; Mw=41000  [identification data]

IDENTIFICATION: SPOT 2970: SeqCov=35%. MascotPMF=81 [1]
SPOT 2986: SeqCov=26%. MascotPMF=50 [1].
MAPPING (identification):
SPOT 2970: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 2986: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP82471; GNAQ_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameGNAQ_RAT
Primary accession numberP82471
Sequence was last modified on July 7, 2009 (version 2)
Annotations were last modified on November 16, 2011 (version 85)
Name and origin of the protein
DescriptionRecName: Full=Guanine nucleotide-binding protein G(q) subunit alpha; AltName: Full=Guanine nucleotide-binding protein alpha-q;
Gene nameName=Gnaq
Encoded onName=Gnaq
KeywordsAcetylation; Complete proteome; GTP-binding; Lipoprotein; Magnesium; Metal-binding; Nucleotide-binding; Palmitate; Reference proteome; Transducer.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAF234260; AAF59930.1; -; mRNA
EMBLL37294; AAB02848.1; -; mRNA
IPIIPI00230868; -; .
RefSeqNP_112298.1; NM_031036.1; .
UniGeneRn.22817; -; .
STRINGP82471; -; .
PhosphoSiteP82471; -; .
World-2DPAGE0004:P82471; -; .
PRIDEP82471; -; .
GeneID81666; -; .
KEGGrno:81666; -; .
CTD2776; -; .
RGD620770; Gnaq; .
eggNOGmaNOG05363; -; .
HOVERGENHBG063184; -; .
InParanoidP82471; -; .
PhylomeDBP82471; -; .
NextBio615248; -; .
ArrayExpressP82471; -; .
GenevestigatorP82471; -; .
GermOnlineENSRNOG00000014183; Rattus norvegicus; .
GOGO:0005901; C:caveola; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome; .
GOGO:0005624; C:membrane fraction; IDA:RGD; .
GOGO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome; .
GOGO:0005525; F:GTP binding; IDA:RGD; .
GOGO:0005096; F:GTPase activator activity; IBA:RefGenome; .
GOGO:0003924; F:GTPase activity; IBA:RefGenome; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0004871; F:signal transducer activity; IBA:RefGenome; .
GOGO:0031826; F:type 2A serotonin receptor binding; IMP:RGD; .
GOGO:0007189; P:activation of adenylate cyclase activity by G-protein signaling pathway; IBA:RefGenome; .
GOGO:0060158; P:activation of phospholipase C activity by dopamine receptor signaling pathway; IBA:RefGenome; .
GOGO:0006916; P:anti-apoptosis; IMP:RGD; .
GOGO:0007215; P:glutamate signaling pathway; IBA:RefGenome; .
GOGO:0043267; P:negative regulation of potassium ion transport; IMP:RGD; .
GOGO:0043065; P:positive regulation of apoptosis; TAS:RGD; .
GOGO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD; .
GOGO:0006471; P:protein ADP-ribosylation; IEA:InterPro; .
GOGO:0001508; P:regulation of action potential; IBA:RefGenome; .
InterProIPR000654; Gprotein_alpha_Q; .
InterProIPR001019; Gprotein_alpha_su; .
InterProIPR011025; GproteinA_insert; .
Gene3DG3DSA:1.10.400.10; GproteinA_insert; 1; .
KOK04634; -; .
PANTHERPTHR10218; Gprotein_alph_bd; 1; .
PfamPF00503; G-alpha; 1; .
SMARTSM00275; G_alpha; 1; .
SUPFAMSSF47895; Transducn_insert; 1; .

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World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server