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Searching in 'World-2DPAGE Repository [0019]' for entry matching: PDIA3_RAT




World-2DPAGE Repository (0019):  PDIA3_RAT

PDIA3_RAT


General information about the entry
View entry in simple text format
Entry namePDIA3_RAT
Primary accession numberP11598
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Protein disulfide-isomerase A3; EC=5.3.4.1; AltName: Full=58 kDa glucose-regulated protein; AltName: Full=58 kDa microsomal protein; Short=p58; AltName: Full=Disulfide isomerase ER-60; AltName: Full=Endoplasmic reticulum resident protein 57; Short=ER protein 57; Short=ERp57; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ER protein 60; Short=ERp60; AltName: Full=HIP-70; AltName: Full=Q-2; Flags: Precursor;.
Gene nameName=Pdia3
Synonyms=Erp60, Grp58
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.88; Mw=57043  [identification data]
pI=5.88; Mw=57043  [identification data]
pI=5.88; Mw=57043  [identification data]

IDENTIFICATION: SPOT 1152: Peptides number=3. SeqCov=5.7%. MOWSE score=7.63E+1 [1]
SPOT 1153: Peptides number=11. SeqCov=24.2%. MOWSE score=9.62E+9 [1]; SPOT 1198: Peptides number=10. SeqCov=23.6%. MOWSE score=1.13E+8 [1].
MAPPING (identification):
SPOT 1152: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1153: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1198: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP11598; PDIA3_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry namePDIA3_RAT
Primary accession numberP11598
Sequence was last modified on February 1, 1996 (version 2)
Annotations were last modified on November 16, 2011 (version 124)
Name and origin of the protein
DescriptionRecName: Full=Protein disulfide-isomerase A3; EC=5.3.4.1; AltName: Full=58 kDa glucose-regulated protein; AltName: Full=58 kDa microsomal protein; Short=p58; AltName: Full=Disulfide isomerase ER-60; AltName: Full=Endoplasmic reticulum resident protein 57; Short=ER protein 57; Short=ERp57; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ER protein 60; Short=ERp60; AltName: Full=HIP-70; AltName: Full=Q-2; Flags: Precursor;
Gene nameName=Pdia3
Synonyms=Erp60, Grp58
Encoded onName=Pdia3; Synonyms=Erp60, Grp58
KeywordsComplete proteome; Direct protein sequencing; Disulfide bond; Endoplasmic reticulum; Isomerase; Redox-active center; Reference proteome; Repeat; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX12355; CAA30916.1; -; mRNA
EMBLD63378; BAA09695.1; -; mRNA
EMBLBC062393; AAH62393.1; -; mRNA
IPIIPI00324741; -; .
PIRA28807; A28807; .
PIRA61354; A61354; .
RefSeqNP_059015.1; NM_017319.1; .
UniGeneRn.11527; -; .
ProteinModelPortalP11598; -; .
SMRP11598; 25-488; .
IntActP11598; 2; .
MINTMINT-4575564; -; .
STRINGP11598; -; .
PhosphoSiteP11598; -; .
World-2DPAGE0004:P11598; -; .
PRIDEP11598; -; .
EnsemblENSRNOT00000020478; ENSRNOP00000020478; ENSRNOG00000015018; .
GeneID29468; -; .
KEGGrno:29468; -; .
UCSCNM_017319; rat; .
CTD2923; -; .
RGD68430; Pdia3; .
eggNOGroNOG09779; -; .
GeneTreeENSGT00590000082864; -; .
HOVERGENHBG005920; -; .
InParanoidP11598; -; .
OrthoDBEOG42Z4PX; -; .
PhylomeDBP11598; -; .
NextBio609284; -; .
ArrayExpressP11598; -; .
GenevestigatorP11598; -; .
GermOnlineENSRNOG00000015018; Rattus norvegicus; .
GOGO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0003756; F:protein disulfide isomerase activity; IEA:EC; .
GOGO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; .
GOGO:0045454; P:cell redox homeostasis; IEA:InterPro; .
GOGO:0006662; P:glycerol ether metabolic process; IEA:InterPro; .
InterProIPR005788; Disulphide_isomerase; .
InterProIPR005792; Prot_disulphide_isomerase; .
InterProIPR005746; Thioredoxin; .
InterProIPR012336; Thioredoxin-like_fold; .
InterProIPR017937; Thioredoxin_CS; .
InterProIPR013766; Thioredoxin_domain; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 3; .
KOK08056; -; .
PfamPF00085; Thioredoxin; 2; .
PRINTSPR00421; THIOREDOXIN; .
SUPFAMSSF52833; Thiordxn-like_fd; 4; .
TIGRFAMsTIGR01130; ER_PDI_fam; 1; .
TIGRFAMsTIGR01126; Pdi_dom; 2; .
PROSITEPS00194; THIOREDOXIN_1; 2; .
PROSITEPS51352; THIOREDOXIN_2; 2; .


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