Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0022]' for entry matching: PHB_RAT World-2DPAGE Repository (0022):  PHB_RAT PHB_RAT General information about the entry View entry in simple text format Entry name PHB_RAT Primary accession number P67779 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=Prohibitin;. Gene name Name=Phb Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 370: pI=5.57; Mw=29859   [identification data] SPOT 383: pI=5.57; Mw=29859   [identification data] IDENTIFICATION: SPOT 370: SeqCov=63.2%. Peptides MS=13/20. Mascot PMF Score=162 [1] SPOT 383: SeqCov=50.4%. Peptides MS=10/20. Mascot PMF Score=111 [1]. PEPTIDE EVIDENCE: SPOT 370: 456-MHPELGSFYDSR-467 (47) / 456-MHPELGSFYDSR-467 Oxidation (M) (53) / 73-GLIDEANQDFTNR-85 (56) [1] SPOT 383: 134-FDAGELITQR-143 (71) / 94-ILFRPVASQLPR-105 (83) / 106-IYTSIGEDYDER-117 (104) [1]. MAPPING (identification): SPOT 370: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]; SPOT 383: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot P67779; PHB_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name PHB_RAT Primary accession number P67779 Secondary accession number(s) P24142 Q4V8M6 Sequence was last modified on  October 11, 2004 (version 1) Annotations were last modified on  September 21, 2011 (version 45) Name and origin of the protein Description RecName: Full=Prohibitin; Gene name Name=Phb Encoded on Name=Phb Keywords Acetylation; Coiled coil; Complete proteome; Direct protein sequencing; DNA synthesis; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M61219; AAA63500.1; -; mRNA EMBL BC072518; AAH72518.1; -; mRNA EMBL BC097304; AAH97304.1; -; mRNA IPI IPI00211756; -; . PIR A39682; A39682; . RefSeq NP_114039.1; NM_031851.2; . UniGene Rn.29754; -; . ProteinModelPortal P67779; -; . IntAct P67779; 1; . PhosphoSite P67779; -; . World-2DPAGE 0004:P67779; -; . PRIDE P67779; -; . GeneID 25344; -; . KEGG rno:25344; -; . CTD 5245; -; . RGD 3322; Phb; . eggNOG maNOG05553; -; . HOVERGEN HBG004457; -; . PhylomeDB P67779; -; . NextBio 606263; -; . Genevestigator P67779; -; . GO GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD; . GO GO:0030061; C:mitochondrial crista; IDA:RGD; . GO GO:0005634; C:nucleus; IDA:RGD; . GO GO:0006260; P:DNA replication; IEA:UniProtKB-KW; . GO GO:0043066; P:negative regulation of apoptosis; IMP:RGD; . GO GO:0008285; P:negative regulation of cell proliferation; IMP:RGD; . GO GO:0031100; P:organ regeneration; IEP:RGD; . GO GO:0001552; P:ovarian follicle atresia; IEP:RGD; . GO GO:0001541; P:ovarian follicle development; IEP:RGD; . GO GO:0034097; P:response to cytokine stimulus; IEP:RGD; . GO GO:0042493; P:response to drug; IEP:RGD; . GO GO:0045471; P:response to ethanol; IEP:RGD; . GO GO:0043434; P:response to peptide hormone stimulus; IEP:RGD; . GO GO:0006950; P:response to stress; IEP:RGD; . InterPro IPR001107; Band_7; . InterPro IPR000163; Prohibitin; . PANTHER PTHR23222; Prohibitin; 1; . Pfam PF01145; Band_7; 1; . PRINTS PR00679; PROHIBITIN; . SMART SM00244; PHB; 1; . World-2DPAGE Repository (search AC)