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Searching in 'World-2DPAGE Repository [0019]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0019):  PP2BA_RAT


PP2BA_RAT


General information about the entry
View entry in simple text format
Entry namePP2BA_RAT
Primary accession numberP63329
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; EC=3.1.3.16; AltName: Full=CAM-PRP catalytic subunit; AltName: Full=Calmodulin-dependent calcineurin A subunit alpha isoform;.
Gene nameName=Ppp3ca
Synonyms=Calna
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.58; Mw=59290  [identification data]
pI=5.58; Mw=59290  [identification data]

IDENTIFICATION: SPOT 370: Peptides number=8. SeqCov=15.4%. MOWSE score=5.97E+7 [1]
SPOT 1154: Peptides number=8. SeqCov=15.5%. MOWSE score=2.66E+6 [1].
MAPPING (identification):
SPOT 370: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1154: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtP63329; PP2BA_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry namePP2BA_RAT
Primary accession numberP63329
Secondary accession number(s) P12816 P20652 Q6LDJ8 Q9WUV7 Q9Z1I5
Sequence was last modified on October 11, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 69)
Name and origin of the protein
DescriptionRecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; EC=3.1.3.16; AltName: Full=CAM-PRP catalytic subunit; AltName: Full=Calmodulin-dependent calcineurin A subunit alpha isoform;
Gene nameName=Ppp3ca
Synonyms=Calna
Encoded onName=Ppp3ca; Synonyms=Calna
KeywordsAlternative splicing; Calmodulin-binding; Complete proteome; Direct protein sequencing; Hydrolase; Iron; Metal-binding; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLD90035; BAA14083.1; -; mRNA
EMBLM29275; AAA40940.1; -; mRNA
EMBLX57115; CAA40398.2; -; mRNA
EMBLD10480; BAA01283.1; -; Genomic_DNA
EMBLM58440; AAA41914.1; -; mRNA
IPIIPI00201410; -; .
IPIIPI00559849; -; .
PIRA33264; A33264; .
RefSeqNP_058737.1; NM_017041.1; .
UniGeneRn.6866; -; .
ProteinModelPortalP63329; -; .
SMRP63329; 1-372; .
STRINGP63329; -; .
PhosphoSiteP63329; -; .
PRIDEP63329; -; .
GeneID24674; -; .
KEGGrno:24674; -; .
UCSCNM_017041; rat; .
CTD5530; -; .
RGD3382; Ppp3ca; .
eggNOGroNOG11256; -; .
GeneTreeENSGT00530000063087; -; .
HOVERGENHBG002819; -; .
InParanoidP63329; -; .
OrthoDBEOG4PVNZK; -; .
PhylomeDBP63329; -; .
NextBio604055; -; .
ArrayExpressP63329; -; .
GenevestigatorP63329; -; .
GermOnlineENSRNOG00000009882; Rattus norvegicus; .
GOGO:0005955; C:calcineurin complex; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0016020; C:membrane; IDA:RGD; .
GOGO:0005634; C:nucleus; IEA:UniProtKB-SubCell; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; IDA:RGD; .
GOGO:0005516; F:calmodulin binding; IDA:RGD; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0046982; F:protein heterodimerization activity; IDA:RGD; .
GOGO:0071333; P:cellular response to glucose stimulus; IMP:BHF-UCL; .
GOGO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IC:BHF-UCL; .
GOGO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL; .
GOGO:0006470; P:protein dephosphorylation; IDA:RGD; .
GOGO:0001975; P:response to amphetamine; IEP:RGD; .
InterProIPR004843; Metallo_PEstase_dom; .
InterProIPR006186; Ser/Thr-sp_prot-phosphatase; .
KOK04348; -; .
PfamPF00149; Metallophos; 1; .
PRINTSPR00114; STPHPHTASE; .
SMARTSM00156; PP2Ac; 1; .
PROSITEPS00125; SER_THR_PHOSPHATASE; 1; .





Searching in 'World-2DPAGE Repository [0001]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0001):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0001)



Searching in 'World-2DPAGE Repository [0002]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0002):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0002)



Searching in 'World-2DPAGE Repository [0003]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0003):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0003)



Searching in 'World-2DPAGE Repository [0004]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0004):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0004)



Searching in 'World-2DPAGE Repository [0005]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0005):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0005)



Searching in 'World-2DPAGE Repository [0006]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0006):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0006)



Searching in 'World-2DPAGE Repository [0007]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0007):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0007)



Searching in 'World-2DPAGE Repository [0008]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0008):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0008)



Searching in 'World-2DPAGE Repository [0009]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0009):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0009)



Searching in 'World-2DPAGE Repository [0010]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0010):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0010)



Searching in 'World-2DPAGE Repository [0011]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0011):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0011)



Searching in 'World-2DPAGE Repository [0012]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0012):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0012)



Searching in 'World-2DPAGE Repository [0014]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0014):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0014)



Searching in 'World-2DPAGE Repository [0017]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0017):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0017)



Searching in 'World-2DPAGE Repository [0018]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0018):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0018)



Searching in 'World-2DPAGE Repository [0020]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0020):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0020)



Searching in 'World-2DPAGE Repository [0021]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0021):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0021)



Searching in 'World-2DPAGE Repository [0022]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0022):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0022)



Searching in 'World-2DPAGE Repository [0023]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0023):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0023)



Searching in 'World-2DPAGE Repository [0024]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0024):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0024)



Searching in 'World-2DPAGE Repository [0026]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0026):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0026)



Searching in 'World-2DPAGE Repository [0027]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0027):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0027)



Searching in 'World-2DPAGE Repository [0029]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0029):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0029)



Searching in 'World-2DPAGE Repository [0030]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0030):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0030)



Searching in 'World-2DPAGE Repository [0031]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0031):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0031)



Searching in 'World-2DPAGE Repository [0032]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0032):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0032)



Searching in 'World-2DPAGE Repository [0034]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0034):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0034)



Searching in 'World-2DPAGE Repository [0035]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0035):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0035)



Searching in 'World-2DPAGE Repository [0036]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0036):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0036)



Searching in 'World-2DPAGE Repository [0037]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0037):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0037)



Searching in 'World-2DPAGE Repository [0038]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0038):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0038)



Searching in 'World-2DPAGE Repository [0039]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0039):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0039)



Searching in 'World-2DPAGE Repository [0040]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0040):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0040)



Searching in 'World-2DPAGE Repository [0042]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0042):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0042)



Searching in 'World-2DPAGE Repository [0043]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0043):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0043)



Searching in 'World-2DPAGE Repository [0044]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0044):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0044)



Searching in 'World-2DPAGE Repository [0046]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0046):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0046)



Searching in 'World-2DPAGE Repository [0047]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0047):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0047)



Searching in 'World-2DPAGE Repository [0050]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0050):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0050)



Searching in 'World-2DPAGE Repository [0051]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0051):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0051)



Searching in 'World-2DPAGE Repository [0053]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0053):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0053)



Searching in 'World-2DPAGE Repository [0054]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0054):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0054)



Searching in 'World-2DPAGE Repository [0056]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0056):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0056)



Searching in 'World-2DPAGE Repository [0059]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0059):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0059)



Searching in 'World-2DPAGE Repository [0061]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0061):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0061)



Searching in 'World-2DPAGE Repository [0062]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0062):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0062)



Searching in 'World-2DPAGE Repository [0063]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0063):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0063)



Searching in 'World-2DPAGE Repository [0066]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0066):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0066)



Searching in 'World-2DPAGE Repository [0068]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0068):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0068)



Searching in 'World-2DPAGE Repository [0069]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0069):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0069)



Searching in 'World-2DPAGE Repository [0076]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0076):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0076)



Searching in 'World-2DPAGE Repository [0077]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0077):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0077)



Searching in 'World-2DPAGE Repository [0080]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0080):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0080)



Searching in 'World-2DPAGE Repository [0084]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0084):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0084)



Searching in 'World-2DPAGE Repository [0085]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0085):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0085)



Searching in 'World-2DPAGE Repository [0088]' for entry matching: PP2BA_RAT




World-2DPAGE Repository (0088):  PP2BA_RAT

This protein does not exist in the current release of World-2DPAGE Repository (0088)




World-2DPAGE Repository image

World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server