World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 517:

pI=6.75; Mw=38000

[identification data]

MAPPING (identification):

SPOT 517: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

P60892; PRPS1_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	PRPS1_RAT
Primary accession number	P60892
Secondary accession number(s)	P09329 Q5M8A4
Sequence was last modified on	January 23, 2007 (version 2)
Annotations were last modified on	November 16, 2011 (version 73)
Name and origin of the protein
Description	RecName: Full=Ribose-phosphate pyrophosphokinase 1; EC=2.7.6.1; AltName: Full=Phosphoribosyl pyrophosphate synthase I; Short=PRS-I;
Gene name	Name=Prps1
Encoded on	Name=Prps1
Keywords	ATP-binding; Complete proteome; Direct protein sequencing; Kinase; Magnesium; Metal-binding; Nucleotide biosynthesis; Nucleotide-binding; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	M17258; AAA41963.1; -; mRNA
EMBL	M29392; AAA41960.1; -; mRNA
EMBL	X16554; CAA34555.1; -; mRNA
EMBL	M31084; AAA41959.1; -; Genomic_DNA
EMBL	M31078; AAA41959.1; JOINED; Genomic_DNA
EMBL	M31079; AAA41959.1; JOINED; Genomic_DNA
EMBL	M31080; AAA41959.1; JOINED; Genomic_DNA
EMBL	M31082; AAA41959.1; JOINED; Genomic_DNA
EMBL	M31083; AAA41959.1; JOINED; Genomic_DNA
EMBL	BC078853; AAH78853.1; -; mRNA
EMBL	BC088149; AAH88149.1; -; mRNA
IPI	IPI00365212; -; .
PIR	A35465; KIRTR1; .
RefSeq	NP_001009694.1; NM_001009694.1; .
RefSeq	NP_058939.1; NM_017243.2; .
UniGene	Rn.91470; -; .
UniGene	Rn.9761; -; .
ProteinModelPortal	P60892; -; .
SMR	P60892; 3-317; .
IntAct	P60892; 1; .
STRING	P60892; -; .
PhosphoSite	P60892; -; .
World-2DPAGE	0004:P60892; -; .
PRIDE	P60892; -; .
Ensembl	ENSRNOT00000029571; ENSRNOP00000029405; ENSRNOG00000025166; .
Ensembl	ENSRNOT00000040360; ENSRNOP00000043734; ENSRNOG00000031938; .
GeneID	29562; -; .
GeneID	314140; -; .
KEGG	rno:29562; -; .
KEGG	rno:314140; -; .
UCSC	NM_017243; rat; .
CTD	5631; -; .
RGD	61955; Prps1; .
eggNOG	roNOG13921; -; .
GeneTree	ENSGT00550000074583; -; .
HOVERGEN	HBG001520; -; .
InParanoid	P60892; -; .
OMA	TIPQDGH; -; .
OrthoDB	EOG4SQWX5; -; .
PhylomeDB	P60892; -; .
NextBio	609618; -; .
ArrayExpress	P60892; -; .
Genevestigator	P60892; -; .
GermOnline	ENSRNOG00000025166; Rattus norvegicus; .
GO	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD; .
GO	GO:0005625; C:soluble fraction; IDA:RGD; .
GO	GO:0043531; F:ADP binding; IDA:RGD; .
GO	GO:0016208; F:AMP binding; IDA:RGD; .
GO	GO:0005524; F:ATP binding; ISS:UniProtKB; .
GO	GO:0019003; F:GDP binding; IDA:RGD; .
GO	GO:0016301; F:kinase activity; IEA:UniProtKB-KW; .
GO	GO:0000287; F:magnesium ion binding; IDA:RGD; .
GO	GO:0042803; F:protein homodimerization activity; ISS:UniProtKB; .
GO	GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB; .
GO	GO:0005529; F:sugar binding; IDA:RGD; .
GO	GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD; .
GO	GO:0006167; P:AMP biosynthetic process; IDA:RGD; .
GO	GO:0009116; P:nucleoside metabolic process; IEA:InterPro; .
GO	GO:0031100; P:organ regeneration; IEP:RGD; .
InterPro	IPR000842; PRib_PP_synth_CS; .
InterPro	IPR000836; PRibTrfase; .
InterPro	IPR005946; Rib-P_diPkinase; .
KO	K00948; -; .
Pfam	PF00156; Pribosyltran; 1; .
TIGRFAMs	TIGR01251; RibP_PPkin; 1; .
PROSITE	PS00114; PRPP_SYNTHASE; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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