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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0014]' for entry matching: PURA_MOUSE

World-2DPAGE Repository (0014):  PURA_MOUSE


General information about the entry
View entry in simple text format
Entry namePURA_MOUSE
Primary accession numberP42669
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Transcriptional activator protein Pur-alpha; AltName: Full=Purine-rich single-stranded DNA-binding protein alpha;.
Gene nameName=Pura
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=6.06; Mw=44000  [identification data]

IDENTIFICATION: SPOT 3350: SeqCov=44%. MascotPMF=82 [1].
MAPPING (identification):
SPOT 3350: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP42669; PURA_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry namePURA_MOUSE
Primary accession numberP42669
Sequence was last modified on November 1, 1995 (version 1)
Annotations were last modified on September 21, 2011 (version 91)
Name and origin of the protein
DescriptionRecName: Full=Transcriptional activator protein Pur-alpha; AltName: Full=Purine-rich single-stranded DNA-binding protein alpha;
Gene nameName=Pura
Encoded onName=Pura
KeywordsAcetylation; Activator; Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU02098; AAA64630.1; -; mRNA
EMBLAF017631; AAB71860.1; -; mRNA
IPIIPI00118447; -; .
RefSeqNP_033015.1; NM_008989.3; .
UniGeneMm.231802; -; .
UniGeneMm.482241; -; .
ProteinModelPortalP42669; -; .
SMRP42669; 57-277; .
IntActP42669; 1; .
STRINGP42669; -; .
PhosphoSiteP42669; -; .
UCD-2DPAGEP42669; -; .
PRIDEP42669; -; .
EnsemblENSMUST00000051301; ENSMUSP00000059404; ENSMUSG00000043991; .
GeneID19290; -; .
KEGGmmu:19290; -; .
UCSCuc008enh.2; mouse; .
CTD5813; -; .
MGIMGI:103079; Pura; .
eggNOGroNOG10448; -; .
HOGENOMHBG383187; -; .
HOVERGENHBG006888; -; .
InParanoidP42669; -; .
OrthoDBEOG4PRSRB; -; .
PhylomeDBP42669; -; .
NextBio459411; -; .
ArrayExpressP42669; -; .
BgeeP42669; -; .
CleanExMM_PURA; -; .
GenevestigatorP42669; -; .
GermOnlineENSMUSG00000043991; Mus musculus; .
GOGO:0005737; C:cytoplasm; IDA:MGI; .
GOGO:0030425; C:dendrite; IDA:MGI; .
GOGO:0005662; C:DNA replication factor A complex; IDA:UniProtKB; .
GOGO:0043025; C:neuronal cell body; IDA:MGI; .
GOGO:0032422; F:purine-rich negative regulatory element binding; IDA:HGNC; .
GOGO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI; .
GOGO:0003697; F:single-stranded DNA binding; IDA:UniProtKB; .
GOGO:0046332; F:SMAD binding; IDA:MGI; .
GOGO:0008134; F:transcription factor binding; IPI:UniProtKB; .
GOGO:0000900; F:translation repressor activity; nucleic acid binding; IDA:HGNC
GOGO:0006915; P:apoptosis; NAS:UniProtKB; .
GOGO:0030154; P:cell differentiation; NAS:UniProtKB; .
GOGO:0008283; P:cell proliferation; NAS:UniProtKB; .
GOGO:0031575; P:mitotic cell cycle G1/S transition checkpoint; NAS:UniProtKB; .
GOGO:0045892; P:negative regulation of transcription; DNA-dependent; IDA:MGI
GOGO:0007399; P:nervous system development; IMP:MGI; .
GOGO:0008284; P:positive regulation of cell proliferation; IMP:MGI; .
InterProIPR006628; PUR_DNA_RNA-bd; .
PfamPF04845; PurA; 1; .
SMARTSM00712; PUR; 3; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server