World-2DPAGE Repository
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World-2DPAGE Repository
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Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0004]' for entry
matching:
PYC_RAT
World-2DPAGE Repository
(0004):
PYC_RAT
PYC_RAT
General information about the entry
View entry in simple text format
Entry name
PYC_RAT
Primary accession number
P52873
integrated into World-2DPAGE Repository (0004) on
October 13, 2008 (release 1)
2D Annotations were last modified on
May 18, 2011 (version 2)
General Annotations were last modified on
December 22, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Pyruvate carboxylase, mitochondrial; EC=6.4.1.1; AltName: Full=Pyruvic carboxylase; Short=PCB; Flags: Precursor;.
Gene name
Name=Pc
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
MAPPING ON GEL
PubMed=19343716; DOI=
10.1002/pmic.200800664
; [
NCBI
,
EBI
,
Israel
,
Japan
]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein
OB21DSUB
{2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
map experimental info
OB21DSUB
MAP LOCATIONS:
SPOT 71
:
pI=6.23; Mw=95000
[identification data]
MAPPING (identification):
SPOT
71
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-Prot
P52873; PYC_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_12
Entry name
PYC_RAT
Primary accession number
P52873
Secondary accession number(s)
Q5RKM0 Q64555
Sequence was last modified on
May 1, 2007 (version 2)
Annotations were last modified on
November 16, 2011 (version 112)
Name and origin of the protein
Description
RecName: Full=Pyruvate carboxylase, mitochondrial; EC=6.4.1.1; AltName: Full=Pyruvic carboxylase; Short=PCB; Flags: Precursor;
Gene name
Name=Pc
Encoded on
Name=Pc
Keywords
Acetylation
;
ATP-binding
;
Biotin
;
Complete proteome
;
Direct protein sequencing
;
Gluconeogenesis
;
Ligase
;
Lipid synthesis
;
Manganese
;
Metal-binding
;
Mitochondrion
;
Multifunctional enzyme
;
Nucleotide-binding
;
Phosphoprotein
;
Pyruvate
;
Reference proteome
;
Transit peptide
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U32314; AAA96256.1
; -; mRNA
EMBL
U36585; AAC52668.1
; -; mRNA
EMBL
BC085680; AAH85680.1
; -; mRNA
IPI
IPI00210435; -
; .
PIR
S68252; JC4391
; .
RefSeq
NP_036876.2; NM_012744.2
; .
UniGene
Rn.11094; -
; .
ProteinModelPortal
P52873; -
; .
SMR
P52873; 35-490
; 494-1178; .
MINT
MINT-4592965; -
; .
STRING
P52873; -
; .
World-2DPAGE
0004:P52873; -
; .
PRIDE
P52873; -
; .
Ensembl
ENSRNOT00000026316; ENSRNOP00000026316
; ENSRNOG00000019372; .
GeneID
25104; -
; .
KEGG
rno:25104; -
; .
NMPDR
fig|10116.3.peg.3454; -
; .
UCSC
NM_012744; rat
; .
CTD
5091; -
; .
RGD
3262; Pc
; .
eggNOG
roNOG05375; -
; .
GeneTree
ENSGT00550000074986; -
; .
HOVERGEN
HBG008340; -
; .
InParanoid
P52873; -
; .
OMA
YKADEAY; -
; .
OrthoDB
EOG4ZCT3P; -
; .
PhylomeDB
P52873; -
; .
NextBio
605431; -
; .
ArrayExpress
P52873; -
; .
Genevestigator
P52873; -
; .
GermOnline
ENSRNOG00000019372; Rattus norvegicus
; .
GO
GO:0005759; C:mitochondrial matrix
; IEA:UniProtKB-SubCell; .
GO
GO:0005625; C:soluble fraction
; IDA:RGD; .
GO
GO:0005524; F:ATP binding
; IDA:RGD; .
GO
GO:0009374; F:biotin binding
; IMP:RGD; .
GO
GO:0004075; F:biotin carboxylase activity
; IEA:InterPro; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0004736; F:pyruvate carboxylase activity
; IDA:RGD; .
GO
GO:0006094; P:gluconeogenesis
; IDA:RGD; .
GO
GO:0008610; P:lipid biosynthetic process
; IEA:UniProtKB-KW; .
GO
GO:0006107; P:oxaloacetate metabolic process
; IDA:RGD; .
GO
GO:0006090; P:pyruvate metabolic process
; IDA:RGD; .
InterPro
IPR013785; Aldolase_TIM
; .
InterPro
IPR011761; ATP-grasp
; .
InterPro
IPR013815; ATP_grasp_subdomain_1
; .
InterPro
IPR013816; ATP_grasp_subdomain_2
; .
InterPro
IPR001882; Biotin_BS
; .
InterPro
IPR011764; Biotin_carboxylation_dom
; .
InterPro
IPR005482; Biotin_COase_C
; .
InterPro
IPR000089; Biotin_lipoyl
; .
InterPro
IPR005479; CarbamoylP_synth_lsu_ATP-bd
; .
InterPro
IPR005481; CarbamoylP_synth_lsu_N
; .
InterPro
IPR003379; Carboxylase_cons_dom
; .
InterPro
IPR013817; Pre-ATP_grasp
; .
InterPro
IPR016185; PreATP-grasp-like
; .
InterPro
IPR000891; PYR_CT
; .
InterPro
IPR005930; Pyruv_COase
; .
InterPro
IPR011054; Rudment_hybrid_motif
; .
InterPro
IPR011053; Single_hybrid_motif
; .
Gene3D
G3DSA:3.20.20.70; Aldolase_TIM
; 1; .
Gene3D
G3DSA:3.30.1490.20; ATP_grasp_subdomain_1
; 1; .
Gene3D
G3DSA:3.30.470.20; ATP_grasp_subdomain_2
; 1; .
Gene3D
G3DSA:3.40.50.20; Pre-ATP_grasp
; 1; .
KO
K01958; -
; .
PANTHER
PTHR18866:SF10; PTHR18866:SF10
; 1; .
Pfam
PF02785; Biotin_carb_C
; 1; .
Pfam
PF00364; Biotin_lipoyl
; 1; .
Pfam
PF00289; CPSase_L_chain
; 1; .
Pfam
PF02786; CPSase_L_D2
; 1; .
Pfam
PF00682; HMGL-like
; 1; .
Pfam
PF02436; PYC_OADA
; 1; .
PIRSF
PIRSF001594; Pyruv_carbox
; 1; .
SMART
SM00878; Biotin_carb_C
; 1; .
SUPFAM
SSF51230; Hybrid_motif
; 1; .
SUPFAM
SSF52440; PreATP-grasp-like
; 1; .
SUPFAM
SSF51246; Rudmnt_hyb_motif
; 1; .
TIGRFAMs
TIGR01235; Pyruv_carbox
; 1; .
PROSITE
PS50975; ATP_GRASP
; 1; .
PROSITE
PS50979; BC
; 1; .
PROSITE
PS00188; BIOTIN
; 1; .
PROSITE
PS50968; BIOTINYL_LIPOYL
; 1; .
PROSITE
PS50991; PYR_CT
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server