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Searching in 'World-2DPAGE Repository [0004]' for entry matching: PYC_RAT World-2DPAGE Repository (0004):  PYC_RAT PYC_RAT General information about the entry View entry in simple text format Entry name PYC_RAT Primary accession number P52873 integrated into World-2DPAGE Repository (0004) on  October 13, 2008 (release 1) 2D Annotations were last modified on May 18, 2011 (version 2) General Annotations were last modified on  December 22, 2011 (version 2) Name and origin of the protein Description RecName: Full=Pyruvate carboxylase, mitochondrial; EC=6.4.1.1; AltName: Full=Pyruvic carboxylase; Short=PCB; Flags: Precursor;. Gene name Name=Pc Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009) 2D PAGE maps for identified proteins How to interpret a protein OB21DSUB {2-DE gel for Olfactory bulb proteome} Rattus norvegicus (Rat) Tissue: Olfactory bulb   map experimental info   OB21DSUB MAP LOCATIONS: SPOT 71: pI=6.23; Mw=95000   [identification data] MAPPING (identification): SPOT 71: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India Cross-references UniProtKB/Swiss-Prot P52873; PYC_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_12 Entry name PYC_RAT Primary accession number P52873 Secondary accession number(s) Q5RKM0 Q64555 Sequence was last modified on  May 1, 2007 (version 2) Annotations were last modified on  November 16, 2011 (version 112) Name and origin of the protein Description RecName: Full=Pyruvate carboxylase, mitochondrial; EC=6.4.1.1; AltName: Full=Pyruvic carboxylase; Short=PCB; Flags: Precursor; Gene name Name=Pc Encoded on Name=Pc Keywords Acetylation; ATP-binding; Biotin; Complete proteome; Direct protein sequencing; Gluconeogenesis; Ligase; Lipid synthesis; Manganese; Metal-binding; Mitochondrion; Multifunctional enzyme; Nucleotide-binding; Phosphoprotein; Pyruvate; Reference proteome; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U32314; AAA96256.1; -; mRNA EMBL U36585; AAC52668.1; -; mRNA EMBL BC085680; AAH85680.1; -; mRNA IPI IPI00210435; -; . PIR S68252; JC4391; . RefSeq NP_036876.2; NM_012744.2; . UniGene Rn.11094; -; . ProteinModelPortal P52873; -; . SMR P52873; 35-490; 494-1178; . MINT MINT-4592965; -; . STRING P52873; -; . World-2DPAGE 0004:P52873; -; . PRIDE P52873; -; . Ensembl ENSRNOT00000026316; ENSRNOP00000026316; ENSRNOG00000019372; . GeneID 25104; -; . KEGG rno:25104; -; . NMPDR fig|10116.3.peg.3454; -; . UCSC NM_012744; rat; . CTD 5091; -; . RGD 3262; Pc; . eggNOG roNOG05375; -; . GeneTree ENSGT00550000074986; -; . HOVERGEN HBG008340; -; . InParanoid P52873; -; . OMA YKADEAY; -; . OrthoDB EOG4ZCT3P; -; . PhylomeDB P52873; -; . NextBio 605431; -; . ArrayExpress P52873; -; . Genevestigator P52873; -; . GermOnline ENSRNOG00000019372; Rattus norvegicus; . GO GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0005524; F:ATP binding; IDA:RGD; . GO GO:0009374; F:biotin binding; IMP:RGD; . GO GO:0004075; F:biotin carboxylase activity; IEA:InterPro; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0004736; F:pyruvate carboxylase activity; IDA:RGD; . GO GO:0006094; P:gluconeogenesis; IDA:RGD; . GO GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW; . GO GO:0006107; P:oxaloacetate metabolic process; IDA:RGD; . GO GO:0006090; P:pyruvate metabolic process; IDA:RGD; . InterPro IPR013785; Aldolase_TIM; . InterPro IPR011761; ATP-grasp; . InterPro IPR013815; ATP_grasp_subdomain_1; . InterPro IPR013816; ATP_grasp_subdomain_2; . InterPro IPR001882; Biotin_BS; . InterPro IPR011764; Biotin_carboxylation_dom; . InterPro IPR005482; Biotin_COase_C; . InterPro IPR000089; Biotin_lipoyl; . InterPro IPR005479; CarbamoylP_synth_lsu_ATP-bd; . InterPro IPR005481; CarbamoylP_synth_lsu_N; . InterPro IPR003379; Carboxylase_cons_dom; . InterPro IPR013817; Pre-ATP_grasp; . InterPro IPR016185; PreATP-grasp-like; . InterPro IPR000891; PYR_CT; . InterPro IPR005930; Pyruv_COase; . InterPro IPR011054; Rudment_hybrid_motif; . InterPro IPR011053; Single_hybrid_motif; . Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1; . Gene3D G3DSA:3.30.1490.20; ATP_grasp_subdomain_1; 1; . Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1; . Gene3D G3DSA:3.40.50.20; Pre-ATP_grasp; 1; . KO K01958; -; . PANTHER PTHR18866:SF10; PTHR18866:SF10; 1; . Pfam PF02785; Biotin_carb_C; 1; . Pfam PF00364; Biotin_lipoyl; 1; . Pfam PF00289; CPSase_L_chain; 1; . Pfam PF02786; CPSase_L_D2; 1; . Pfam PF00682; HMGL-like; 1; . Pfam PF02436; PYC_OADA; 1; . PIRSF PIRSF001594; Pyruv_carbox; 1; . SMART SM00878; Biotin_carb_C; 1; . SUPFAM SSF51230; Hybrid_motif; 1; . SUPFAM SSF52440; PreATP-grasp-like; 1; . SUPFAM SSF51246; Rudmnt_hyb_motif; 1; . TIGRFAMs TIGR01235; Pyruv_carbox; 1; . PROSITE PS50975; ATP_GRASP; 1; . PROSITE PS50979; BC; 1; . PROSITE PS00188; BIOTIN; 1; . PROSITE PS50968; BIOTINYL_LIPOYL; 1; . PROSITE PS50991; PYR_CT; 1; . World-2DPAGE Repository (search AC)