Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

Q01986:

ID   MP2K1_RAT;
AC   Q01986;
DT   09-Dec-2009, integrated into Rat hippocampal synaptoproteome (release 1).
DT   30-May-2011, 2D annotation version 2.
DT   13-Jan-2012, general annotation version 2.
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1;
DE   Short=MAP kinase kinase 1; Short=MAPKK 1; EC=2.7.12.2; AltName: Full=ERK
DE   activator kinase 1; AltName: Full=MAPK/ERK kinase 1; Short=MEK 1;.
GN   Name=Map2k1; Synonyms=Mek1, Prkmk1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
IM   HIPP_SYNAP.
RN   [1]
RP   2D-PAGE GEL CHARACTERIZATION.
RX   DOI=10.1111/j.1471-4159.2010.06719.x;
RA   VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.;
RT   ''Aging alters the expression of neurotransmission-regulating proteins in
RT   the hippocampal synaptoproteome'';
RL   J of Neurochemistry 113(6):1577-1588 (2010).
2D   -!- MASTER: HIPP_SYNAP;
2D   -!-   PI/MW: SPOT 540=6.18/43779;
2D   -!-   PI/MW: SPOT 541=6.18/43779;
2D   -!-   PI/MW: SPOT 543=6.18/43779;
2D   -!-   PI/MW: SPOT 1177=6.18/43779;
2D   -!-   IDENTIFICATION: SPOT 540: Peptides number=4. SeqCov=9.4%. MOWSE
2D         score=1.95E+2 [1]; SPOT 541: Peptides number=2. SeqCov=6.4%. MOWSE
2D         score=1.95E+2 [1]; SPOT 543: Peptides number=3. SeqCov=9.4%. MOWSE
2D         score=7.89E+1 [1]; SPOT 1177: Peptides number=4. SeqCov=6.4%. MOWSE
2D         score=4.62E+2 [1].
2D   -!-   MAPPING: SPOT 540: Peptide mass fingerprinting [1]; SPOT 540:
2D         Tandem mass spectrometry [1]; SPOT 541: Peptide mass fingerprinting [1];
2D         SPOT 541: Tandem mass spectrometry [1]; SPOT 543: Peptide mass
2D         fingerprinting [1]; SPOT 543: Tandem mass spectrometry [1]; SPOT 1177:
2D         Peptide mass fingerprinting [1]; SPOT 1177: Tandem mass spectrometry [1].
CC   ---------------------------------------------------------------------------
CC   Data from Dr. Willard Freeman, Penn State College of Medicine, USA
CC   ---------------------------------------------------------------------------
DR   UniProtKB/Swiss-Prot; Q01986; MP2K1_RAT.
//

The following 2-D map is available for this protein:

	Rat hippocampal synaptoproteome

World-2DPAGE Repository (search AC)