resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained.
It will be discontinued on 31-May-2024.

World-2DPAGE Repository no longer accepts submissions.

World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]


use 'Ctrl' to select several

Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'World-2DPAGE Repository [0043]' for entry matching: Q02566

World-2DPAGE Repository (0043):  Q02566


General information about the entry
View entry in simple text format
Entry nameMYH6_MOUSE
Primary accession numberQ02566
integrated into World-2DPAGE Repository (0043) on January 4, 2012 (release 1)
2D Annotations were last modified onJanuary 6, 2012 (version 1)
General Annotations were last modified on April 18, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Myosin-6; AltName: Full=Myosin heavy chain 6; AltName: Full=Myosin heavy chain, cardiac muscle alpha isoform; Short=MyHC-alpha;.
Gene nameName=Myh6
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
DOI=10.1016/j.jprot.2012.04.001 ;
Sun Z., Biela L.M., Hamilton K.L., Reardon K.F.
''Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes''
Journal of Proteomics 0(0):0-0 (2012)
2D PAGE maps for identified proteins
How to interpret a protein

MMUSCULUS_HL-1PHI_4-7 {mouse HL-1 cultured cardiomyocytes hydrophilic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=224225  [identification data]

%COV: BAND phi12: 15.8 [1].
SCORE: BAND phi12: 126 [1].
SEARCH ENGINE: BAND phi12: Mascot [1].
MAPPING (identification):
BAND phi12: Tandem mass spectrometry [1].

MMUSCULUS_HL-1PHO_4-7 {mouse HL-1 cultured cardiomyocytes hydrophobic extraction}
Mus musculus (Mouse)
Tissue: Cardiac myocyte
  map experimental info

Mw=51854  [identification data]

%COV: BAND pho26: 7.69 [1].
SCORE: BAND pho26: 343 [1].
SEARCH ENGINE: BAND pho26: Mascot [1].
MAPPING (identification):
BAND pho26: Tandem mass spectrometry [1].

Data from Dr. Zeyu Sun, Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, USA
UniProtKB/Swiss-ProtQ02566; MYH6_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2012_03
Entry nameMYH6_MOUSE
Primary accession numberQ02566
Secondary accession number(s) Q64258 Q64738
Sequence was last modified on July 15, 1998 (version 2)
Annotations were last modified on February 22, 2012 (version 101)
Name and origin of the protein
DescriptionRecName: Full=Myosin-6; AltName: Full=Myosin heavy chain 6; AltName: Full=Myosin heavy chain, cardiac muscle alpha isoform; Short=MyHC-alpha;
Gene nameName=Myh6
Encoded onName=Myh6; Synonyms=Myhca
KeywordsActin-binding; ATP-binding; Calmodulin-binding; Coiled coil; Complete proteome; Cytoplasm; Isopeptide bond; Methylation; Motor protein; Muscle protein; Myosin; Nucleotide-binding; Polymorphism; Reference proteome; Thick filament; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM76598; AAA37159.1; -; mRNA
EMBLM76599; AAA37160.1; -; mRNA
EMBLM76600; AAA37161.1; -; mRNA
EMBLM76601; AAA37162.1; -; mRNA
EMBLM62404; AAA37424.1; -; Genomic_DNA
IPIIPI00129404; -; .
PIRI49464; I49464; .
RefSeqNP_001157643.1; NM_001164171.1; .
RefSeqNP_034986.1; NM_010856.4; .
UniGeneMm.290003; -; .
ProteinModelPortalQ02566; -; .
SMRQ02566; 3-843; 852-963; .
IntActQ02566; 1; .
STRINGQ02566; -; .
PhosphoSiteQ02566; -; .
SWISS-2DPAGEQ02566; -; .
PRIDEQ02566; -; .
EnsemblENSMUST00000081857; ENSMUSP00000080538; ENSMUSG00000040752; .
GeneID17888; -; .
KEGGmmu:17888; -; .
CTD4624; -; .
MGIMGI:97255; Myh6; .
eggNOGCOG5022; -; .
GeneTreeENSGT00650000093197; -; .
HOGENOMHBG717149; -; .
HOVERGENHBG004704; -; .
InParanoidQ02566; -; .
KOK10352; -; .
PhylomeDBQ02566; -; .
NextBio292705; -; .
ArrayExpressQ02566; -; .
BgeeQ02566; -; .
GenevestigatorQ02566; -; .
GermOnlineENSMUSG00000040752; Mus musculus; .
GOGO:0032982; C:myosin filament; IEA:UniProtKB-KW; .
GOGO:0001725; C:stress fiber; IDA:MGI; .
GOGO:0030018; C:Z disc; IDA:MGI; .
GOGO:0003779; F:actin binding; IEA:UniProtKB-KW; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0005516; F:calmodulin binding; IEA:UniProtKB-KW; .
GOGO:0000146; F:microfilament motor activity; IMP:MGI; .
GOGO:0007512; P:adult heart development; IMP:MGI; .
GOGO:0030509; P:BMP signaling pathway; IDA:MGI; .
GOGO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI; .
GOGO:0048739; P:cardiac muscle fiber development; IMP:MGI; .
GOGO:0001701; P:in utero embryonic development; IMP:MGI; .
GOGO:0043462; P:regulation of ATPase activity; IMP:MGI; .
GOGO:0008217; P:regulation of blood pressure; IMP:MGI; .
GOGO:0002027; P:regulation of heart rate; IMP:MGI; .
GOGO:0002026; P:regulation of the force of heart contraction; IMP:MGI; .
GOGO:0045214; P:sarcomere organization; IMP:MGI; .
GOGO:0006941; P:striated muscle contraction; IMP:MGI; .
GOGO:0007522; P:visceral muscle development; IMP:MGI; .
InterProIPR000048; IQ_motif_EF-hand-BS; .
InterProIPR015650; Myosin_hc; .
InterProIPR001609; Myosin_head_motor_dom; .
InterProIPR004009; Myosin_N; .
InterProIPR002928; Myosin_tail; .
PANTHERPTHR13140:SF22; Myosin_hc; 1; .
PfamPF00063; Myosin_head; 1; .
PfamPF02736; Myosin_N; 1; .
PfamPF01576; Myosin_tail_1; 1; .
SMARTSM00015; IQ; 2; .
SMARTSM00242; MYSc; 1; .
PROSITEPS50096; IQ; 1; .

World-2DPAGE Repository image

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server