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Searching in 'World-2DPAGE Repository [0030]' for entry matching: Q07439

World-2DPAGE Repository (0030):  Q07439


General information about the entry
View entry in simple text format
Entry nameHSP71_RAT
Primary accession numberQ07439
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Heat shock 70 kDa protein 1A/1B; AltName: Full=Heat shock 70 kDa protein 1/2; Short=HSP70-1/HSP70-2; Short=HSP70.1/HSP70.2;.
Gene nameName=Hspa1a
Synonyms=Hsp70-1, Hspa1
Synonyms=Hsp70-2, Hspa2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=5.60; Mw=77361  [identification data]
pI=4.60; Mw=75877  [identification data]
pI=4.58; Mw=74421  [identification data]

IDENTIFICATION: SPOT 596: Mascot protein score=92. Number of peptides=2 [1]
SPOT 631: Mascot protein score=231. Number of peptides=4 [1]; SPOT 672: Mascot protein score=59. Number of peptides=2 [1].
MAPPING (identification):
SPOT 596: Tandem mass spectrometry [1];
SPOT 631: Tandem mass spectrometry [1];
SPOT 672: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtQ07439; HSP71_RAT.
World-2DPAGE RepositoryQ07439; HSP71_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameHSP71_RAT
Primary accession numberQ07439
Secondary accession number(s) P42853 Q63256
Sequence was last modified on November 23, 2004 (version 2)
Annotations were last modified on November 16, 2011 (version 95)
Name and origin of the protein
DescriptionRecName: Full=Heat shock 70 kDa protein 1A/1B; AltName: Full=Heat shock 70 kDa protein 1/2; Short=HSP70-1/HSP70-2; Short=HSP70.1/HSP70.2;
Gene nameName=Hspa1a
Synonyms=Hsp70-1, Hspa1
Synonyms=Hsp70-2, Hspa2
Encoded onName=Hspa1a; Synonyms=Hsp70-1, Hspa1; and Name=Hspa1b; Synonyms=Hsp70-2, Hspa2
KeywordsAcetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Phosphoprotein; Reference proteome; Stress response.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLL16764; AAA17441.1; -; mRNA
EMBLX77208; CAA54423.1; -; Genomic_DNA
EMBLX77207; CAA54422.1; -; Genomic_DNA
EMBLX74271; CAA52328.1; -; Genomic_DNA
EMBLX75357; CAA53140.1; -; Genomic_DNA
EMBLBX883045; CAE83977.1; -; Genomic_DNA
EMBLBX883045; CAE83978.1; -; Genomic_DNA
IPIIPI00196751; -; .
PIRI54542; I54542; .
RefSeqNP_114177.2; NM_031971.2; .
RefSeqNP_997669.1; NM_212504.1; .
UniGeneRn.1950; -; .
ProteinModelPortalQ07439; -; .
SMRQ07439; 1-619; .
MINTMINT-240978; -; .
STRINGQ07439; -; .
PhosphoSiteQ07439; -; .
PRIDEQ07439; -; .
GeneID24472; -; .
GeneID294254; -; .
KEGGrno:24472; -; .
KEGGrno:294254; -; .
UCSCNM_212504; rat; .
CTD3303; -; .
CTD3304; -; .
RGD1593284; Hspa1a; .
RGD2840; Hspa1b; .
eggNOGmaNOG16200; -; .
GeneTreeENSGT00550000074467; -; .
HOVERGENHBG051845; -; .
InParanoidQ07439; -; .
OrthoDBEOG4W6NVK; -; .
PhylomeDBQ07439; -; .
NextBio603417; -; .
ArrayExpressQ07439; -; .
GenevestigatorQ07439; -; .
GermOnlineENSRNOG00000033526; Rattus norvegicus; .
GOGO:0016324; C:apical plasma membrane; IDA:RGD; .
GOGO:0016323; C:basolateral plasma membrane; IDA:RGD; .
GOGO:0005829; C:cytosol; IDA:RGD; .
GOGO:0016607; C:nuclear speck; ISS:UniProtKB; .
GOGO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0051059; F:NF-kappaB binding; IPI:RGD; .
GOGO:0002020; F:protease binding; IPI:RGD; .
GOGO:0006952; P:defense response; IDA:RGD; .
GOGO:0006402; P:mRNA catabolic process; ISS:UniProtKB; .
GOGO:0043066; P:negative regulation of apoptosis; IDA:RGD; .
GOGO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:RGD; .
GOGO:0030308; P:negative regulation of cell growth; ISS:UniProtKB; .
GOGO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB; .
GOGO:0045906; P:negative regulation of vasoconstriction; IMP:RGD; .
GOGO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:RGD; .
GOGO:0009612; P:response to mechanical stimulus; IEP:RGD; .
GOGO:0006986; P:response to unfolded protein; ISS:UniProtKB; .
InterProIPR018181; Heat_shock_70_CS; .
InterProIPR001023; Hsp70; .
InterProIPR013126; Hsp_70; .
KOK03283; -; .
PANTHERPTHR19375; Hsp70; 1; .
PfamPF00012; HSP70; 1; .
PROSITEPS00297; HSP70_1; 1; .
PROSITEPS00329; HSP70_2; 1; .
PROSITEPS01036; HSP70_3; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server