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Searching in 'World-2DPAGE Repository [0022]' for entry matching: Q07936




World-2DPAGE Repository (0022):  Q07936


Q07936


General information about the entry
View entry in simple text format
Entry nameANXA2_RAT
Primary accession numberQ07936
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Annexin A2; AltName: Full=Annexin II; AltName: Full=Annexin-2; AltName: Full=Calpactin I heavy chain; AltName: Full=Calpactin-1 heavy chain; AltName: Full=Chromobindin-8; AltName: Full=Lipocortin II; AltName: Full=Placental anticoagulant protein IV; Short=PAP-IV; AltName: Full=Protein I; AltName: Full=p36;.
Gene nameName=Anxa2
Synonyms=Anx2
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=7.55; Mw=38939  [identification data]

IDENTIFICATION: SPOT 930: SeqCov=43.7%. Peptides MS=10/20. Mascot PMF Score=93 [1].
PEPTIDE EVIDENCE: SPOT 930: 69-QDIAFAYQR-77 (45) / 50-GVDEVTIVNILTNR-63 (74) / 120-GLGTDEDSLIEIICSR-135 (30) [1].
MAPPING (identification):
SPOT 930: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtQ07936; ANXA2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameANXA2_RAT
Primary accession numberQ07936
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on September 21, 2011 (version 110)
Name and origin of the protein
DescriptionRecName: Full=Annexin A2; AltName: Full=Annexin II; AltName: Full=Annexin-2; AltName: Full=Calpactin I heavy chain; AltName: Full=Calpactin-1 heavy chain; AltName: Full=Chromobindin-8; AltName: Full=Lipocortin II; AltName: Full=Placental anticoagulant protein IV; Short=PAP-IV; AltName: Full=Protein I; AltName: Full=p36;
Gene nameName=Anxa2
Synonyms=Anx2
Encoded onName=Anxa2; Synonyms=Anx2
KeywordsAcetylation; Alternative splicing; Annexin; Basement membrane; Calcium; Calcium/phospholipid-binding; Complete proteome; Direct protein sequencing; Extracellular matrix; Phosphoprotein; Reference proteome; Repeat; Secreted; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX66871; CAA47343.1; -; mRNA
EMBLL13039; AAA40741.1; -; mRNA
EMBLS73559; AAB31934.2; -; mRNA
EMBLS73557; AAB31933.2; -; mRNA
EMBLBC059136; AAH59136.1; -; mRNA
IPIIPI00325146; -; .
IPIIPI00829462; -; .
PIRS33700; S33700; .
PIRS55277; S55277; .
RefSeqNP_063970.1; NM_019905.1; .
UniGeneRn.90546; -; .
ProteinModelPortalQ07936; -; .
SMRQ07936; 21-339; .
IntActQ07936; 2; .
STRINGQ07936; -; .
PhosphoSiteQ07936; -; .
PRIDEQ07936; -; .
EnsemblENSRNOT00000038677; ENSRNOP00000038428; ENSRNOG00000010362; .
GeneID56611; -; .
KEGGrno:56611; -; .
UCSCNM_019905; rat; .
UCSCS73557; rat; .
CTD302; -; .
RGD621170; Anxa2; .
eggNOGroNOG14532; -; .
GeneTreeENSGT00590000082810; -; .
HOVERGENHBG061815; -; .
OrthoDBEOG4KD6MM; -; .
PhylomeDBQ07936; -; .
NextBio611122; -; .
ArrayExpressQ07936; -; .
GenevestigatorQ07936; -; .
GermOnlineENSRNOG00000010362; Rattus norvegicus; .
GOGO:0005604; C:basement membrane; IEA:UniProtKB-SubCell; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0048471; C:perinuclear region of cytoplasm; IDA:RGD; .
GOGO:0043234; C:protein complex; IDA:RGD; .
GOGO:0051015; F:actin filament binding; TAS:RGD; .
GOGO:0005509; F:calcium ion binding; TAS:RGD; .
GOGO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW; .
GOGO:0005546; F:phosphatidylinositol-4; 5-bisphosphate binding; IDA:RGD
GOGO:0004859; F:phospholipase inhibitor activity; IEA:InterPro; .
GOGO:0017137; F:Rab GTPase binding; IPI:RGD; .
GOGO:0007589; P:body fluid secretion; IMP:RGD; .
GOGO:0051917; P:regulation of fibrinolysis; TAS:RGD; .
InterProIPR001464; Annexin; .
InterProIPR018502; Annexin_repeat; .
InterProIPR018252; Annexin_repeat_CS; .
InterProIPR002389; AnnexinII; .
Gene3DG3DSA:1.10.220.10; Annexin; 4; .
PANTHERPTHR10502; Annexin; 1; .
PANTHERPTHR10502:SF18; AnnexinII; 1; .
PfamPF00191; Annexin; 4; .
PRINTSPR00196; ANNEXIN; .
PRINTSPR00198; ANNEXINII; .
SMARTSM00335; ANX; 4; .
SUPFAMSSF47874; Annexin; 1; .
PROSITEPS00223; ANNEXIN; 4; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server