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Searching in 'World-2DPAGE Repository [0022]' for entry matching: Q2TA68




World-2DPAGE Repository (0022):  Q2TA68


Q2TA68


General information about the entry
View entry in simple text format
Entry nameOPA1_RAT
Primary accession numberQ2TA68
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Dynamin-like 120 kDa protein, mitochondrial; AltName: Full=Optic atrophy protein 1 homolog; Contains: RecName: Full=Dynamin-like 120 kDa protein, form S1; Flags: Precursor;.
Gene nameName=Opa1
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=7.17; Mw=111751  [identification data]

IDENTIFICATION: SPOT 623: SeqCov=14%. Peptides MS=11/20. Mascot PMF Score=53 [1].
PEPTIDE EVIDENCE: SPOT 623: 528-LLKTSMLK-535 Oxidation (M) (1) / 615-HWEEILQQSLWER-627 (44) / 669-AVEVAWETLQDEFSR-683 (84) [1].
MAPPING (identification):
SPOT 623: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtQ2TA68; OPA1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameOPA1_RAT
Primary accession numberQ2TA68
Secondary accession number(s) O08681 Q5MPP1 Q5MPP2 Q5QJE9 Q6B435 Q6R611
Sequence was last modified on January 24, 2006 (version 1)
Annotations were last modified on September 21, 2011 (version 51)
Name and origin of the protein
DescriptionRecName: Full=Dynamin-like 120 kDa protein, mitochondrial; AltName: Full=Optic atrophy protein 1 homolog; Contains: RecName: Full=Dynamin-like 120 kDa protein, form S1; Flags: Precursor;
Gene nameName=Opa1
Encoded onName=Opa1
KeywordsAcetylation; Alternative splicing; Apoptosis; Coiled coil; Complete proteome; Direct protein sequencing; GTP-binding; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Sensory transduction; Transit peptide; Transmembrane; Transmembrane helix.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAY333988; AAR04100.1; -; mRNA
EMBLAY660011; AAV97815.1; -; mRNA
EMBLAY660012; AAV97816.1; -; mRNA
EMBLAY510274; AAS79791.1; -; mRNA
EMBLBC111071; AAI11072.1; -; mRNA
EMBLU93197; AAB51724.1; ALT_INIT; mRNA
EMBLAY683458; AAT92526.1; -; mRNA
IPIIPI00192639; -; .
IPIIPI00421659; -; .
IPIIPI00798619; -; .
RefSeqNP_598269.3; NM_133585.3; .
UniGeneRn.9783; -; .
ProteinModelPortalQ2TA68; -; .
IntActQ2TA68; 1; .
STRINGQ2TA68; -; .
PhosphoSiteQ2TA68; -; .
PRIDEQ2TA68; -; .
GeneID171116; -; .
KEGGrno:171116; -; .
CTD4976; -; .
RGD708423; Opa1; .
eggNOGroNOG09941; -; .
GeneTreeENSGT00550000074851; -; .
HOVERGENHBG019108; -; .
InParanoidQ2TA68; -; .
NextBio621844; -; .
PMAP-CutDBQ2TA68; -; .
ArrayExpressQ2TA68; -; .
GenevestigatorQ2TA68; -; .
GermOnlineENSRNOG00000001717; Rattus norvegicus; .
GOGO:0016021; C:integral to membrane; IEA:UniProtKB-KW; .
GOGO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell; .
GOGO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0006915; P:apoptosis; IEA:UniProtKB-KW; .
GOGO:0050896; P:response to stimulus; IEA:UniProtKB-KW; .
GOGO:0007601; P:visual perception; IEP:RGD; .
InterProIPR022812; Dynamin; .
InterProIPR001401; Dynamin_GTPase; .
PfamPF00350; Dynamin_N; 1; .
PRINTSPR00195; DYNAMIN; .
SMARTSM00053; DYNc; 1; .
PROSITEPS00410; DYNAMIN; FALSE_NEG; .



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