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Searching in 'World-2DPAGE Repository [0014]' for entry matching: Q3T1J1

World-2DPAGE Repository (0014):  Q3T1J1


General information about the entry
View entry in simple text format
Entry nameIF5A1_RAT
Primary accession numberQ3T1J1
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=eIF-4D;.
Gene nameName=Eif5a
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=5.30; Mw=16000  [identification data]

IDENTIFICATION: SPOT 3269: SeqCov=46%. MascotPMF=75 [1].
MAPPING (identification):
SPOT 3269: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtQ3T1J1; IF5A1_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameIF5A1_RAT
Primary accession numberQ3T1J1
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 61)
Name and origin of the protein
DescriptionRecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=eIF-4D;
Gene nameName=Eif5a
Encoded onName=Eif5a
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; Endoplasmic reticulum; Hypusine; Membrane; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Protein biosynthesis; Protein transport; Reference proteome; RNA-binding; Translocation; Transport.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLBC101891; AAI01892.1; -; mRNA
IPIIPI00211216; -; .
RefSeqNP_001028853.1; NM_001033681.1; .
UniGeneRn.128212; -; .
ProteinModelPortalQ3T1J1; -; .
SMRQ3T1J1; 15-150; .
IntActQ3T1J1; 1; .
STRINGQ3T1J1; -; .
PhosphoSiteQ3T1J1; -; .
PRIDEQ3T1J1; -; .
EnsemblENSRNOT00000022343; ENSRNOP00000022343; ENSRNOG00000016478; .
GeneID287444; -; .
KEGGrno:287444; -; .
UCSCNM_001033681; rat; .
CTD1984; -; .
RGD1308029; Eif5a; .
eggNOGmaNOG16112; -; .
GeneTreeENSGT00390000003738; -; .
HOVERGENHBG001104; -; .
InParanoidQ3T1J1; -; .
OrthoDBEOG41JZDF; -; .
PhylomeDBQ3T1J1; -; .
NextBio626163; -; .
ArrayExpressQ3T1J1; -; .
GenevestigatorQ3T1J1; -; .
GermOnlineENSRNOG00000016478; Rattus norvegicus; .
GOGO:0030425; C:dendrite; IDA:RGD; .
GOGO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell; .
GOGO:0043025; C:neuronal cell body; IDA:RGD; .
GOGO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell; .
GOGO:0043022; F:ribosome binding; IEA:InterPro; .
GOGO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW; .
GOGO:0007568; P:aging; IEP:RGD; .
GOGO:0051028; P:mRNA transport; IEA:UniProtKB-KW; .
GOGO:0043066; P:negative regulation of apoptosis; IMP:RGD; .
GOGO:0008612; P:peptidyl-lysine modification to hypusine; IEA:InterPro; .
GOGO:0051149; P:positive regulation of muscle cell differentiation; IMP:RGD; .
GOGO:0045901; P:positive regulation of translational elongation; IEA:InterPro; .
GOGO:0045905; P:positive regulation of translational termination; IEA:InterPro; .
GOGO:0015031; P:protein transport; IEA:UniProtKB-KW; .
GOGO:0006452; P:translational frameshifting; IEA:InterPro; .
InterProIPR005824; KOW; .
InterProIPR012340; NA-bd_OB-fold; .
InterProIPR016027; NA-bd_OB-fold-like; .
InterProIPR019769; Trans_elong_IF5A_hypusine_site; .
InterProIPR001884; Transl_elong_IF5A; .
InterProIPR020189; Transl_elong_IF5A_C; .
InterProIPR014722; Transl_SH3-like_sub; .
InterProIPR008991; Translation_prot_SH3-like; .
Gene3DG3DSA:; OB_NA_bd_sub; 1; .
Gene3DG3DSA:; Ribosomal_L2; 1; .
KOK03263; -; .
PANTHERPTHR11673; EIF5A_hypusine; 1; .
PfamPF01287; eIF-5a; 1; .
PfamPF00467; KOW; 1; .
PIRSFPIRSF003025; eIF5A; 1; .
SUPFAMSSF50249; Nucleic_acid_OB; 1; .
SUPFAMSSF50104; Transl_SH3_like; 1; .
TIGRFAMsTIGR00037; EIF_5A; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server