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World-2DPAGE Repository
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Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
Exclude local DBs
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Searching in 'World-2DPAGE Repository [0014]' for entry
matching:
Q5I0C3
World-2DPAGE Repository
(0014):
Q5I0C3
Q5I0C3
General information about the entry
View entry in simple text format
Entry name
MCCA_RAT
Primary accession number
Q5I0C3
integrated into World-2DPAGE Repository (0014) on
October 13, 2008 (release 1)
2D Annotations were last modified on
June 1, 2011 (version 3)
General Annotations were last modified on
November 25, 2011 (version 2)
Name and origin of the protein
Description
RecName: Full=Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Short=MCCase subunit alpha; EC=6.4.1.4; AltName: Full=3-methylcrotonyl-CoA carboxylase 1; AltName: Full=3-methylcrotonyl-CoA carboxylase biotin-containing subunit; AltName: Full=3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; Flags: Precursor;.
Gene name
Name=Mccc1
Synonyms=Mcca
Annotated species
Rattus norvegicus (Rat) [TaxID:
10116
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]
2D-PAGE GEL CHARACTERIZATION
DOI=
10.1002/pmic.200900680
;
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein
RAT_CEREBELLUM_21D
{Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
map experimental info
RAT_CEREBELLUM_21D
MAP LOCATIONS:
SPOT 3357
:
pI=6.35; Mw=81000
[identification data]
IDENTIFICATION:
SPOT 3357: SeqCov=35%. MascotPMF=119 [
1
].
MAPPING (identification):
SPOT
3357
:
Peptide mass fingerprinting
[
1
];
Tandem mass spectrometry
[
1
].
Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
PRIDE
10017.
UniProtKB/Swiss-Prot
Q5I0C3; MCCA_RAT.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
2011_11
Entry name
MCCA_RAT
Primary accession number
Q5I0C3
Sequence was last modified on
February 15, 2005 (version 1)
Annotations were last modified on
November 16, 2011 (version 61)
Name and origin of the protein
Description
RecName: Full=Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Short=MCCase subunit alpha; EC=6.4.1.4; AltName: Full=3-methylcrotonyl-CoA carboxylase 1; AltName: Full=3-methylcrotonyl-CoA carboxylase biotin-containing subunit; AltName: Full=3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; Flags: Precursor;
Gene name
Name=Mccc1
Synonyms=Mcca
Encoded on
Name=Mccc1; Synonyms=Mcca
Keywords
ATP-binding
;
Biotin
;
Complete proteome
;
Ligase
;
Mitochondrion
;
Nucleotide-binding
;
Reference proteome
;
Transit peptide
.
Copyright
Copyrighted by the UniProt Consortium, see
https://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
BC088473; AAH88473.1
; -; mRNA
IPI
IPI00372191; -
; .
RefSeq
NP_001009653.1; NM_001009653.1
; .
UniGene
Rn.15587; -
; .
HSSP
P24182; 1BNC
; .
ProteinModelPortal
Q5I0C3; -
; .
SMR
Q5I0C3; 641-714
; .
STRING
Q5I0C3; -
; .
PhosphoSite
Q5I0C3; -
; .
PRIDE
Q5I0C3; -
; .
GeneID
294972; -
; .
KEGG
rno:294972; -
; .
UCSC
NM_001009653; rat
; .
CTD
56922; -
; .
RGD
1310615; Mccc1
; .
eggNOG
roNOG07266; -
; .
GeneTree
ENSGT00550000074675; -
; .
HOVERGEN
HBG000555; -
; .
InParanoid
Q5I0C3; -
; .
OrthoDB
EOG4WQ123; -
; .
NextBio
638797; -
; .
ArrayExpress
Q5I0C3; -
; .
Genevestigator
Q5I0C3; -
; .
GO
GO:0005759; C:mitochondrial matrix
; IEA:UniProtKB-SubCell; .
GO
GO:0005524; F:ATP binding
; IEA:UniProtKB-KW; .
GO
GO:0004075; F:biotin carboxylase activity
; IEA:InterPro; .
GO
GO:0046872; F:metal ion binding
; IEA:InterPro; .
GO
GO:0004485; F:methylcrotonoyl-CoA carboxylase activity
; IEA:EC; .
InterPro
IPR011761; ATP-grasp
; .
InterPro
IPR013815; ATP_grasp_subdomain_1
; .
InterPro
IPR013816; ATP_grasp_subdomain_2
; .
InterPro
IPR001882; Biotin_BS
; .
InterPro
IPR011764; Biotin_carboxylation_dom
; .
InterPro
IPR005482; Biotin_COase_C
; .
InterPro
IPR000089; Biotin_lipoyl
; .
InterPro
IPR005479; CarbamoylP_synth_lsu_ATP-bd
; .
InterPro
IPR005481; CarbamoylP_synth_lsu_N
; .
InterPro
IPR013817; Pre-ATP_grasp
; .
InterPro
IPR016185; PreATP-grasp-like
; .
InterPro
IPR011054; Rudment_hybrid_motif
; .
InterPro
IPR011053; Single_hybrid_motif
; .
Gene3D
G3DSA:3.30.1490.20; ATP_grasp_subdomain_1
; 1; .
Gene3D
G3DSA:3.30.470.20; ATP_grasp_subdomain_2
; 1; .
Gene3D
G3DSA:3.40.50.20; Pre-ATP_grasp
; 1; .
KO
K01968; -
; .
Pfam
PF02785; Biotin_carb_C
; 1; .
Pfam
PF00364; Biotin_lipoyl
; 1; .
Pfam
PF00289; CPSase_L_chain
; 1; .
Pfam
PF02786; CPSase_L_D2
; 1; .
SMART
SM00878; Biotin_carb_C
; 1; .
SUPFAM
SSF51230; Hybrid_motif
; 1; .
SUPFAM
SSF52440; PreATP-grasp-like
; 1; .
SUPFAM
SSF51246; Rudmnt_hyb_motif
; 1; .
PROSITE
PS50975; ATP_GRASP
; 1; .
PROSITE
PS50979; BC
; 1; .
PROSITE
PS00188; BIOTIN
; 1; .
PROSITE
PS50968; BIOTINYL_LIPOYL
; 1; .
PROSITE
PS00866; CPSASE_1
; FALSE_NEG; .
PROSITE
PS00867; CPSASE_2
; 1; .
World-2DPAGE Repository (search AC)
Database constructed and maintained by
SIB
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
Expasy web server