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Searching in 'World-2DPAGE Repository [0014]' for entry matching: Q5RJQ4

World-2DPAGE Repository (0014):  Q5RJQ4


General information about the entry
View entry in simple text format
Entry nameSIRT2_RAT
Primary accession numberQ5RJQ4
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=NAD-dependent deacetylase sirtuin-2; EC=3.5.1.-; AltName: Full=SIR2-like protein 2;.
Gene nameName=Sirt2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=6.87; Mw=38000  [identification data]

IDENTIFICATION: SPOT 3015: SeqCov=43%. MascotPMF=156 [1].
MAPPING (identification):
SPOT 3015: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtQ5RJQ4; SIRT2_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameSIRT2_RAT
Primary accession numberQ5RJQ4
Sequence was last modified on December 21, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 61)
Name and origin of the protein
DescriptionRecName: Full=NAD-dependent deacetylase sirtuin-2; EC=3.5.1.-; AltName: Full=SIR2-like protein 2;
Gene nameName=Sirt2
Encoded onName=Sirt2; Synonyms=Sir2l2
KeywordsCell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Hydrolase; Metal-binding; Microtubule; Mitosis; NAD; Phosphoprotein; Reference proteome; Zinc.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLBC086545; AAH86545.1; -; mRNA
IPIIPI00950048; -; .
RefSeqNP_001008369.1; NM_001008368.1; .
UniGeneRn.59887; -; .
ProteinModelPortalQ5RJQ4; -; .
PhosphoSiteQ5RJQ4; -; .
EnsemblENSRNOT00000064153; ENSRNOP00000059450; ENSRNOG00000020102; .
GeneID361532; -; .
KEGGrno:361532; -; .
UCSCNM_001008368; rat; .
CTD22933; -; .
RGD621481; Sirt2; .
eggNOGroNOG16591; -; .
GeneTreeENSGT00550000074608; -; .
HOVERGENHBG057095; -; .
InParanoidQ5RJQ4; -; .
PhylomeDBQ5RJQ4; -; .
NextBio676633; -; .
ArrayExpressQ5RJQ4; -; .
GenevestigatorQ5RJQ4; -; .
GermOnlineENSRNOG00000020102; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; ISS:UniProtKB; .
GOGO:0005874; C:microtubule; IEA:UniProtKB-KW; .
GOGO:0016811; F:hydrolase activity; acting on carbon-nitrogen (but not peptide) bonds; in linear amides
GOGO:0070403; F:NAD+ binding; IEA:InterPro; .
GOGO:0008270; F:zinc ion binding; IEA:InterPro; .
GOGO:0051301; P:cell division; IEA:UniProtKB-KW; .
GOGO:0006342; P:chromatin silencing; IEA:InterPro; .
GOGO:0007067; P:mitosis; IEA:UniProtKB-KW; .
GOGO:0006476; P:protein deacetylation; IEA:InterPro; .
InterProIPR017328; NAD-dep_deAcase_SIR2_euk; .
InterProIPR003000; NAD-dep_deAcase_sirtuin; .
KOK11412; -; .
PANTHERPTHR11085; SIR2; 1; .
PfamPF02146; SIR2; 1; .
PIRSFPIRSF037938; SIR2_euk; 1; .

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