Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: Q63081 World-2DPAGE Repository (0030):  Q63081 Q63081 General information about the entry View entry in simple text format Entry name PDIA6_RAT Primary accession number Q63081 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1; AltName: Full=Calcium-binding protein 1; Short=CaBP1; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;. Gene name Name=Pdia6 Synonyms=Cabp1, Txndc7 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 1017: pI=5.02; Mw=62086   [identification data] SPOT 1088: pI=4.97; Mw=59727   [identification data] SPOT 1090: pI=5.13; Mw=59727   [identification data] SPOT 1101: pI=5.02; Mw=59398   [identification data] SPOT 1837: pI=4.85; Mw=35849   [identification data] IDENTIFICATION: SPOT 1017: Mascot protein score=214. Number of peptides=10 [1] SPOT 1088: Mascot protein score=162. Number of peptides=5 [1]; SPOT 1090: Mascot protein score=317. Number of peptides=5 [1]; SPOT 1101: Mascot protein score=295. Number of peptides=4 [1]; SPOT 1837: Mascot protein score=139. Number of peptides=3 [1]. MAPPING (identification): SPOT 1017: Tandem mass spectrometry [1]; SPOT 1088: Tandem mass spectrometry [1]; SPOT 1090: Tandem mass spectrometry [1]; SPOT 1101: Tandem mass spectrometry [1]; SPOT 1837: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot Q63081; PDIA6_RAT. World-2DPAGE Repository Q63081; PDIA6_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name PDIA6_RAT Primary accession number Q63081 Secondary accession number(s) Q641Y3 Sequence was last modified on  March 29, 2005 (version 2) Annotations were last modified on  November 16, 2011 (version 97) Name and origin of the protein Description RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1; AltName: Full=Calcium-binding protein 1; Short=CaBP1; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor; Gene name Name=Pdia6 Synonyms=Cabp1, Txndc7 Encoded on Name=Pdia6; Synonyms=Cabp1, Txndc7 Keywords Calcium; Cell membrane; Chaperone; Complete proteome; Direct protein sequencing; Disulfide bond; Endoplasmic reticulum; Isomerase; Membrane; Phosphoprotein; Redox-active center; Reference proteome; Repeat; Signal. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC082063; AAH82063.1; ALT_INIT; mRNA EMBL X79328; CAA55891.1; -; mRNA IPI IPI00365929; -; . PIR S45038; S45038; . RefSeq NP_001004442.1; NM_001004442.1; . UniGene Rn.2685; -; . ProteinModelPortal Q63081; -; . SMR Q63081; 20-132; 154-280; . IntAct Q63081; 1; . MINT MINT-1775443; -; . PhosphoSite Q63081; -; . PRIDE Q63081; -; . GeneID 286906; -; . KEGG rno:286906; -; . UCSC BC082063; rat; . CTD 10130; -; . RGD 628688; Pdia6; . HOVERGEN HBG053548; -; . NextBio 625007; -; . Genevestigator Q63081; -; . GO GO:0005788; C:endoplasmic reticulum lumen; IDA:HGNC; . GO GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; TAS:RGD; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0005509; F:calcium ion binding; TAS:RGD; . GO GO:0009055; F:electron carrier activity; IEA:InterPro; . GO GO:0003756; F:protein disulfide isomerase activity; IEA:EC; . GO GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; . GO GO:0045454; P:cell redox homeostasis; IEA:InterPro; . GO GO:0006662; P:glycerol ether metabolic process; IEA:InterPro; . GO GO:0006457; P:protein folding; TAS:RGD; . InterPro IPR005788; Disulphide_isomerase; . InterPro IPR005746; Thioredoxin; . InterPro IPR012336; Thioredoxin-like_fold; . InterPro IPR017937; Thioredoxin_CS; . InterPro IPR013766; Thioredoxin_domain; . Gene3D G3DSA:3.40.30.10; Thioredoxin_fold; 2; . KO K09584; -; . Pfam PF00085; Thioredoxin; 2; . PRINTS PR00421; THIOREDOXIN; . SUPFAM SSF52833; Thiordxn-like_fd; 3; . TIGRFAMs TIGR01126; Pdi_dom; 2; . PROSITE PS00014; ER_TARGET; 1; . PROSITE PS00194; THIOREDOXIN_1; 2; . PROSITE PS51352; THIOREDOXIN_2; 2; . World-2DPAGE Repository (search AC)