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Searching in 'World-2DPAGE Repository [0030]' for entry matching: Q63081




World-2DPAGE Repository (0030):  Q63081


Q63081


General information about the entry
View entry in simple text format
Entry namePDIA6_RAT
Primary accession numberQ63081
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1; AltName: Full=Calcium-binding protein 1; Short=CaBP1; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;.
Gene nameName=Pdia6
Synonyms=Cabp1, Txndc7
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info
 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=5.02; Mw=62086  [identification data]
pI=4.97; Mw=59727  [identification data]
pI=5.13; Mw=59727  [identification data]
pI=5.02; Mw=59398  [identification data]
pI=4.85; Mw=35849  [identification data]

IDENTIFICATION: SPOT 1017: Mascot protein score=214. Number of peptides=10 [1]
SPOT 1088: Mascot protein score=162. Number of peptides=5 [1]; SPOT 1090: Mascot protein score=317. Number of peptides=5 [1]; SPOT 1101: Mascot protein score=295. Number of peptides=4 [1]; SPOT 1837: Mascot protein score=139. Number of peptides=3 [1].
MAPPING (identification):
SPOT 1017: Tandem mass spectrometry [1];
SPOT 1088: Tandem mass spectrometry [1];
SPOT 1090: Tandem mass spectrometry [1];
SPOT 1101: Tandem mass spectrometry [1];
SPOT 1837: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtQ63081; PDIA6_RAT.
World-2DPAGE RepositoryQ63081; PDIA6_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry namePDIA6_RAT
Primary accession numberQ63081
Secondary accession number(s) Q641Y3
Sequence was last modified on March 29, 2005 (version 2)
Annotations were last modified on November 16, 2011 (version 97)
Name and origin of the protein
DescriptionRecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1; AltName: Full=Calcium-binding protein 1; Short=CaBP1; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;
Gene nameName=Pdia6
Synonyms=Cabp1, Txndc7
Encoded onName=Pdia6; Synonyms=Cabp1, Txndc7
KeywordsCalcium; Cell membrane; Chaperone; Complete proteome; Direct protein sequencing; Disulfide bond; Endoplasmic reticulum; Isomerase; Membrane; Phosphoprotein; Redox-active center; Reference proteome; Repeat; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLBC082063; AAH82063.1; ALT_INIT; mRNA
EMBLX79328; CAA55891.1; -; mRNA
IPIIPI00365929; -; .
PIRS45038; S45038; .
RefSeqNP_001004442.1; NM_001004442.1; .
UniGeneRn.2685; -; .
ProteinModelPortalQ63081; -; .
SMRQ63081; 20-132; 154-280; .
IntActQ63081; 1; .
MINTMINT-1775443; -; .
PhosphoSiteQ63081; -; .
PRIDEQ63081; -; .
GeneID286906; -; .
KEGGrno:286906; -; .
UCSCBC082063; rat; .
CTD10130; -; .
RGD628688; Pdia6; .
HOVERGENHBG053548; -; .
NextBio625007; -; .
GenevestigatorQ63081; -; .
GOGO:0005788; C:endoplasmic reticulum lumen; IDA:HGNC; .
GOGO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; TAS:RGD; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0005509; F:calcium ion binding; TAS:RGD; .
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0003756; F:protein disulfide isomerase activity; IEA:EC; .
GOGO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; .
GOGO:0045454; P:cell redox homeostasis; IEA:InterPro; .
GOGO:0006662; P:glycerol ether metabolic process; IEA:InterPro; .
GOGO:0006457; P:protein folding; TAS:RGD; .
InterProIPR005788; Disulphide_isomerase; .
InterProIPR005746; Thioredoxin; .
InterProIPR012336; Thioredoxin-like_fold; .
InterProIPR017937; Thioredoxin_CS; .
InterProIPR013766; Thioredoxin_domain; .
Gene3DG3DSA:3.40.30.10; Thioredoxin_fold; 2; .
KOK09584; -; .
PfamPF00085; Thioredoxin; 2; .
PRINTSPR00421; THIOREDOXIN; .
SUPFAMSSF52833; Thiordxn-like_fd; 3; .
TIGRFAMsTIGR01126; Pdi_dom; 2; .
PROSITEPS00014; ER_TARGET; 1; .
PROSITEPS00194; THIOREDOXIN_1; 2; .
PROSITEPS51352; THIOREDOXIN_2; 2; .



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