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Searching in 'World-2DPAGE Repository [0022]' for entry matching: Q66HF1 World-2DPAGE Repository (0022):  Q66HF1 Q66HF1 General information about the entry View entry in simple text format Entry name NDUS1_RAT Primary accession number Q66HF1 integrated into World-2DPAGE Repository (0022) on  May 7, 2010 (release 1) 2D Annotations were last modified on June 22, 2011 (version 2) General Annotations were last modified on  November 24, 2011 (version 2) Name and origin of the protein Description RecName: Full=NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; EC=1.6.5.3; EC=1.6.99.3; Flags: Precursor;. Gene name Name=Ndufs1 Annotated species Rattus [TaxID: 10114] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000593; Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L. ''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity'' Proteomics 11(16):3369-3379 (2011) 2D PAGE maps for identified proteins How to interpret a protein HCR_LCR_HEART {HCR LCR Cardiac Map} Rattus Tissue: Heart   map experimental info   HCR_LCR_HEART MAP LOCATIONS: SPOT 607: pI=5.65; Mw=80331   [identification data] SPOT 920: pI=5.65; Mw=80331   [identification data] IDENTIFICATION: SPOT 607: SeqCov=30.7%. Peptides MS=18/20. Mascot PMF Score=185 [1] SPOT 920: SeqCov=24.9%. Peptides MS=14/20. Mascot PMF Score=122 [1]. MAPPING (identification): SPOT 607: Peptide mass fingerprinting [1]; SPOT 920: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1]. Copyright Data from Dr. Jatin Burniston, Liverpool John Moores University, UK Cross-references UniProtKB/Swiss-Prot Q66HF1; NDUS1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name NDUS1_RAT Primary accession number Q66HF1 Sequence was last modified on  October 11, 2004 (version 1) Annotations were last modified on  November 16, 2011 (version 64) Name and origin of the protein Description RecName: Full=NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; EC=1.6.5.3; EC=1.6.99.3; Flags: Precursor; Gene name Name=Ndufs1 Encoded on Name=Ndufs1 Keywords 2Fe-2S; 4Fe-4S; Acetylation; Complete proteome; Direct protein sequencing; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Reference proteome; Respiratory chain; Transit peptide; Transport; Ubiquinone. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BC081892; AAH81892.1; -; mRNA IPI IPI00358033; -; . RefSeq NP_001005550.1; NM_001005550.1; . UniGene Rn.1467; -; . HSSP Q56223; 2FUG; . ProteinModelPortal Q66HF1; -; . STRING Q66HF1; -; . PhosphoSite Q66HF1; -; . PRIDE Q66HF1; -; . Ensembl ENSRNOT00000015852; ENSRNOP00000015851; ENSRNOG00000011849; . GeneID 301458; -; . KEGG rno:301458; -; . NMPDR fig|10116.3.peg.30141; -; . UCSC NM_001005550; rat; . CTD 4719; -; . RGD 1359670; Ndufs1; . eggNOG roNOG09474; -; . GeneTree ENSGT00390000018768; -; . HOVERGEN HBG003482; -; . InParanoid Q66HF1; -; . OMA DSDSLCT; -; . OrthoDB EOG4D26PC; -; . PhylomeDB Q66HF1; -; . NextBio 648791; -; . ArrayExpress Q66HF1; -; . Genevestigator Q66HF1; -; . GO GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB; . GO GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB; . GO GO:0051537; F:2 iron; 2 sulfur cluster binding; IEA:UniProtKB-KW GO GO:0051539; F:4 iron; 4 sulfur cluster binding; IEA:UniProtKB-KW GO GO:0009055; F:electron carrier activity; IEA:InterPro; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IBA:RefGenome; . GO GO:0006915; P:apoptosis; ISS:UniProtKB; . GO GO:0046034; P:ATP metabolic process; ISS:UniProtKB; . GO GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro; . GO GO:0072593; P:reactive oxygen species metabolic process; ISS:UniProtKB; . GO GO:0051881; P:regulation of mitochondrial membrane potential; ISS:UniProtKB; . GO GO:0006810; P:transport; IEA:UniProtKB-KW; . InterPro IPR012675; Beta-grasp_ferredoxin-type; . InterPro IPR001041; Ferredoxin; . InterPro IPR006656; Mopterin_OxRdtase; . InterPro IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS; . InterPro IPR010228; NADH_UbQ_OxRdtase_Gsu; . InterPro IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd; . InterPro IPR015405; NuoG_C; . Gene3D G3DSA:3.10.20.30; Ferredoxin_fold; 1; . KO K03934; -; . Pfam PF09326; DUF1982; 1; . Pfam PF00111; Fer2; 1; . Pfam PF00384; Molybdopterin; 1; . Pfam PF10588; NADH-G_4Fe-4S_3; 1; . SMART SM00929; NADH-G_4Fe-4S_3; 1; . SUPFAM SSF54292; Ferredoxin; 1; . TIGRFAMs TIGR01973; NuoG; 1; . PROSITE PS51085; 2FE2S_FER_2; 1; . PROSITE PS00641; COMPLEX1_75K_1; 1; . PROSITE PS00642; COMPLEX1_75K_2; 1; . PROSITE PS00643; COMPLEX1_75K_3; 1; . World-2DPAGE Repository (search AC)