resource logo

World-2DPAGE Repository

Attention: World-2DPAGE is no longer maintained.

World-2DPAGE Repository no longer accepts submissions.


World-2DPAGE Repository 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Databases

use 'Ctrl' to select several
databases


Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal

Exclude local DBs
has only effect if a remote
interface is selected
     
Searching in 'World-2DPAGE Repository [0019]' for entry matching: Q6AYZ1




World-2DPAGE Repository (0019):  Q6AYZ1


Q6AYZ1


General information about the entry
View entry in simple text format
Entry nameTBA1C_RAT
Primary accession numberQ6AYZ1
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain;.
Gene nameName=Tuba1c
Synonyms=Tuba6
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=4.96; Mw=50589  [identification data]
pI=4.94; Mw=50803  [identification data]
pI=4.96; Mw=50589  [identification data]
pI=4.96; Mw=50589  [identification data]

IDENTIFICATION: SPOT 463: Peptides number=8. SeqCov=24.5%. MOWSE score=4.28E+11 [1]
SPOT 601: Peptides number=9. SeqCov=29%. MOWSE score=3.12E+7 [1]; SPOT 825: Peptides number=3. SeqCov=8.5%. MOWSE score=1.55E+3 [1]; SPOT 1166: Peptides number=5. SeqCov=16.9%. MOWSE score=6.28E+8 [1].
MAPPING (identification):
SPOT 463: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 601: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 825: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1166: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtQ6AYZ1; TBA1C_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameTBA1C_RAT
Primary accession numberQ6AYZ1
Sequence was last modified on September 13, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 65)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain;
Gene nameName=Tuba1c
Synonyms=Tuba6
Encoded onName=Tuba1c; Synonyms=Tuba6
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLBC078829; AAH78829.1; -; mRNA
IPIIPI00364046; -; .
RefSeqNP_001011995.1; NM_001011995.1; .
UniGeneRn.154526; -; .
ProteinModelPortalQ6AYZ1; -; .
SMRQ6AYZ1; 1-439; .
STRINGQ6AYZ1; -; .
PhosphoSiteQ6AYZ1; -; .
EnsemblENSRNOT00000020932; ENSRNOP00000020932; ENSRNOG00000015544; .
GeneID300218; -; .
KEGGrno:300218; -; .
UCSCNM_001011995; rat; .
CTD84790; -; .
RGD1307226; Tuba1c; .
eggNOGmaNOG08063; -; .
GeneTreeENSGT00600000084100; -; .
HOVERGENHBG000089; -; .
InParanoidQ6AYZ1; -; .
OrthoDBEOG44J2HZ; -; .
PhylomeDBQ6AYZ1; -; .
ReactomeREACT_115492; Developmental Biology; .
NextBio646554; -; .
ArrayExpressQ6AYZ1; -; .
GenevestigatorQ6AYZ1; -; .
GermOnlineENSRNOG00000015544; Rattus norvegicus; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR002452; Alpha_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:1.10.287.600; Tubulin_C; 1; .
Gene3DG3DSA:3.40.50.1440; Tubulin_FtsZ; 1; .
KOK07374; -; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
PRINTSPR01162; ALPHATUBULIN; .
PRINTSPR01161; TUBULIN; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .
PROSITEPS00227; TUBULIN; 1; .



World-2DPAGE Repository image

World-2DPAGE Repository (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server