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World-2DPAGE Repository

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Searching in 'World-2DPAGE Repository [0019]' for entry matching: Q6AYZ1

World-2DPAGE Repository (0019):  Q6AYZ1


General information about the entry
View entry in simple text format
Entry nameTBA1C_RAT
Primary accession numberQ6AYZ1
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain;.
Gene nameName=Tuba1c
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
  map experimental info

pI=4.96; Mw=50589  [identification data]
pI=4.94; Mw=50803  [identification data]
pI=4.96; Mw=50589  [identification data]
pI=4.96; Mw=50589  [identification data]

IDENTIFICATION: SPOT 463: Peptides number=8. SeqCov=24.5%. MOWSE score=4.28E+11 [1]
SPOT 601: Peptides number=9. SeqCov=29%. MOWSE score=3.12E+7 [1]; SPOT 825: Peptides number=3. SeqCov=8.5%. MOWSE score=1.55E+3 [1]; SPOT 1166: Peptides number=5. SeqCov=16.9%. MOWSE score=6.28E+8 [1].
MAPPING (identification):
SPOT 463: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 601: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 825: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1166: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Willard Freeman, Penn State College of Medicine, USA
UniProtKB/Swiss-ProtQ6AYZ1; TBA1C_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameTBA1C_RAT
Primary accession numberQ6AYZ1
Sequence was last modified on September 13, 2004 (version 1)
Annotations were last modified on November 16, 2011 (version 65)
Name and origin of the protein
DescriptionRecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain;
Gene nameName=Tuba1c
Encoded onName=Tuba1c; Synonyms=Tuba6
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLBC078829; AAH78829.1; -; mRNA
IPIIPI00364046; -; .
RefSeqNP_001011995.1; NM_001011995.1; .
UniGeneRn.154526; -; .
ProteinModelPortalQ6AYZ1; -; .
SMRQ6AYZ1; 1-439; .
PhosphoSiteQ6AYZ1; -; .
EnsemblENSRNOT00000020932; ENSRNOP00000020932; ENSRNOG00000015544; .
GeneID300218; -; .
KEGGrno:300218; -; .
UCSCNM_001011995; rat; .
CTD84790; -; .
RGD1307226; Tuba1c; .
eggNOGmaNOG08063; -; .
GeneTreeENSGT00600000084100; -; .
HOVERGENHBG000089; -; .
InParanoidQ6AYZ1; -; .
OrthoDBEOG44J2HZ; -; .
PhylomeDBQ6AYZ1; -; .
ReactomeREACT_115492; Developmental Biology; .
NextBio646554; -; .
ArrayExpressQ6AYZ1; -; .
GenevestigatorQ6AYZ1; -; .
GermOnlineENSRNOG00000015544; Rattus norvegicus; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR002452; Alpha_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:; Tubulin_C; 1; .
Gene3DG3DSA:; Tubulin_FtsZ; 1; .
KOK07374; -; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .

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World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server