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Searching in 'World-2DPAGE Repository [0014]' for entry matching: Q8CFN2

World-2DPAGE Repository (0014):  Q8CFN2


General information about the entry
View entry in simple text format
Entry nameCDC42_RAT
Primary accession numberQ8CFN2
integrated into World-2DPAGE Repository (0014) on October 13, 2008 (release 1)
2D Annotations were last modified onJune 1, 2011 (version 3)
General Annotations were last modified on November 25, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Cell division control protein 42 homolog; Flags: Precursor;.
Gene nameName=Cdc42
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of whole cerebellum of the mature rat''
Proteomics 10(23):4311-4319 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_CEREBELLUM_21D {Proteome of 21 days old rat cerebellum}
Rattus norvegicus (Rat)
Tissue: Cerebellum
  map experimental info

pI=6.32; Mw=23000  [identification data]

IDENTIFICATION: SPOT 3207: SeqCov=54%. MascotPMF=118 [1].
MAPPING (identification):
SPOT 3207: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtQ8CFN2; CDC42_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameCDC42_RAT
Primary accession numberQ8CFN2
Secondary accession number(s) Q6P9Y3 Q71TW5
Sequence was last modified on January 9, 2007 (version 2)
Annotations were last modified on November 16, 2011 (version 74)
Name and origin of the protein
DescriptionRecName: Full=Cell division control protein 42 homolog; Flags: Precursor;
Gene nameName=Cdc42
Encoded onName=Cdc42
KeywordsAcetylation; Alternative splicing; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Differentiation; Direct protein sequencing; GTP-binding; Lipoprotein; Membrane; Methylation; Neurogenesis; Nucleotide-binding; Prenylation; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAF205635; AAF15538.1; -; mRNA
EMBLAF491841; AAN63806.1; -; mRNA
EMBLBC060535; AAH60535.1; -; mRNA
IPIIPI00285606; -; .
IPIIPI00388289; -; .
RefSeqNP_741991.3; NM_171994.4; .
UniGeneRn.60067; -; .
HSSPP60953; 1AM4; .
ProteinModelPortalQ8CFN2; -; .
SMRQ8CFN2; 1-191; .
MINTMINT-3381856; -; .
PhosphoSiteQ8CFN2; -; .
EnsemblENSRNOT00000018118; ENSRNOP00000018118; ENSRNOG00000013536; .
EnsemblENSRNOT00000029025; ENSRNOP00000030928; ENSRNOG00000013536; .
GeneID64465; -; .
KEGGrno:64465; -; .
CTD998; -; .
RGD71043; Cdc42; .
eggNOGroNOG07751; -; .
GeneTreeENSGT00560000076570; -; .
HOVERGENHBG009351; -; .
InParanoidQ8CFN2; -; .
OrthoDBEOG4R23VV; -; .
PhylomeDBQ8CFN2; -; .
NextBio613224; -; .
ArrayExpressQ8CFN2; -; .
GenevestigatorQ8CFN2; -; .
GOGO:0000139; C:Golgi membrane; IDA:RGD; .
GOGO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; .
GOGO:0030496; C:midbody; ISS:UniProtKB; .
GOGO:0072686; C:mitotic spindle; ISS:UniProtKB; .
GOGO:0005886; C:plasma membrane; IDA:UniProtKB; .
GOGO:0051233; C:spindle midzone; ISS:UniProtKB; .
GOGO:0030141; C:stored secretory granule; IDA:UniProtKB; .
GOGO:0005525; F:GTP binding; TAS:UniProtKB; .
GOGO:0003924; F:GTPase activity; TAS:RGD; .
GOGO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD; .
GOGO:0030010; P:establishment of cell polarity; TAS:RGD; .
GOGO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB; .
GOGO:0045740; P:positive regulation of DNA replication; IMP:RGD; .
GOGO:0046330; P:positive regulation of JNK cascade; IDA:RGD; .
GOGO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB; .
GOGO:0017157; P:regulation of exocytosis; TAS:UniProtKB; .
GOGO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB; .
GOGO:0009749; P:response to glucose stimulus; TAS:UniProtKB; .
GOGO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro; .
InterProIPR005225; Small_GTP-bd_dom; .
InterProIPR001806; Small_GTPase; .
InterProIPR003578; Small_GTPase_Rho; .
KOK04393; -; .
PfamPF00071; Ras; 1; .
SMARTSM00174; RHO; 1; .
TIGRFAMsTIGR00231; Small_GTP; 1; .
PROSITEPS51420; RHO; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server