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Searching in 'World-2DPAGE Repository [0027]' for entry matching: Q8K2B3




World-2DPAGE Repository (0027):  Q8K2B3


Q8K2B3


General information about the entry
View entry in simple text format
Entry nameDHSA_MOUSE
Primary accession numberQ8K2B3
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; EC=1.3.5.1; AltName: Full=Flavoprotein subunit of complex II; Short=Fp; Flags: Precursor;.
Gene nameName=Sdha
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/prca.201000103;
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
GIPRDN_4-7
  map experimental info
 
GIPRDN_4-7

MAP LOCATIONS:
pI=6.32; Mw=78000  [identification data]

EXPRESSION:
SPOT 3: Avg ratio GIPRdn-tg vs. control=1.62 (p-value=0.0063) [1].

IDENTIFICATION: SPOT 3: SeqCov=27%. Mascot protein score=291 [1].
MAPPING (identification):
SPOT 3: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
Cross-references
REPRODUCTION-2DPAGEQ8K2B3; Q8K2B3.
UniProtKB/Swiss-ProtQ8K2B3; DHSA_MOUSE.
World-2DPAGE RepositoryQ8K2B3; DHSA_MOUSE.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameDHSA_MOUSE
Primary accession numberQ8K2B3
Secondary accession number(s) Q0QF19 Q3UH25 Q3UKP7 Q3V4B1 Q921P5 Q9Z1Z4
Sequence was last modified on October 1, 2002 (version 1)
Annotations were last modified on November 16, 2011 (version 89)
Name and origin of the protein
DescriptionRecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; EC=1.3.5.1; AltName: Full=Flavoprotein subunit of complex II; Short=Fp; Flags: Precursor;
Gene nameName=Sdha
Encoded onName=Sdha
KeywordsAcetylation; Complete proteome; Direct protein sequencing; Electron transport; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Phosphoprotein; Reference proteome; Transit peptide; Transport; Tricarboxylic acid cycle; Tumor suppressor.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAK029520; BAC26491.1; -; mRNA
EMBLAK034928; BAC28884.1; -; mRNA
EMBLAK049590; BAC33831.1; -; mRNA
EMBLAK050475; BAC34276.1; -; mRNA
EMBLAK075990; BAC36101.1; -; mRNA
EMBLAK145923; BAE26754.1; -; mRNA
EMBLAK147286; BAE27822.1; -; mRNA
EMBLAK147624; BAE28032.1; -; mRNA
EMBLAK153085; BAE31710.1; -; mRNA
EMBLAK162148; BAE36754.1; -; mRNA
EMBLAK169254; BAE41018.1; -; mRNA
EMBLAK004362; BAE43173.1; -; mRNA
EMBLBC011301; AAH11301.1; -; mRNA
EMBLBC031849; AAH31849.1; -; mRNA
EMBLDQ402975; ABD77308.1; -; mRNA
EMBLAF095938; AAC72373.1; -; mRNA
IPIIPI00230351; -; .
RefSeqNP_075770.1; NM_023281.1; .
UniGeneMm.158231; -; .
ProteinModelPortalQ8K2B3; -; .
SMRQ8K2B3; 52-664; .
IntActQ8K2B3; 2; .
STRINGQ8K2B3; -; .
PhosphoSiteQ8K2B3; -; .
REPRODUCTION-2DPAGEQ8K2B3; -; .
PRIDEQ8K2B3; -; .
EnsemblENSMUST00000022062; ENSMUSP00000022062; ENSMUSG00000021577; .
GeneID66945; -; .
KEGGmmu:66945; -; .
NMPDRfig|10090.3.peg.28133; -; .
UCSCuc007rfa.1; mouse; .
CTD6389; -; .
MGIMGI:1914195; Sdha; .
eggNOGroNOG09792; -; .
GeneTreeENSGT00390000010046; -; .
HOVERGENHBG001461; -; .
InParanoidQ8K2B3; -; .
OMAPFCWEEA; -; .
OrthoDBEOG47H5PJ; -; .
PhylomeDBQ8K2B3; -; .
NextBio323092; -; .
ArrayExpressQ8K2B3; -; .
BgeeQ8K2B3; -; .
GenevestigatorQ8K2B3; -; .
GermOnlineENSMUSG00000021577; Mus musculus; .
GOGO:0005749; C:mitochondrial respiratory chain complex II; ISS:UniProtKB; .
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro; .
GOGO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:EC; .
GOGO:0022904; P:respiratory electron transport chain; ISS:UniProtKB; .
GOGO:0006105; P:succinate metabolic process; ISS:UniProtKB; .
GOGO:0006810; P:transport; IEA:UniProtKB-KW; .
GOGO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW; .
InterProIPR003953; FAD_bind2_N; .
InterProIPR003952; FRD_SDH_FAD_BS; .
InterProIPR015939; Fum_Rdtase/Succ_DH_flav-like_C; .
InterProIPR004112; Fum_Rdtase/Succ_DH_flav_C; .
InterProIPR011281; Succ_DH_flav_su_fwd; .
InterProIPR014006; Succ_Dhase_FrdA_Gneg; .
Gene3DG3DSA:1.20.58.100; Fum_Rdtase/Succ_DH_flav-like_C; 1; .
KOK00234; -; .
PfamPF00890; FAD_binding_2; 1; .
PfamPF02910; Succ_DH_flav_C; 1; .
SUPFAMSSF46977; Succ_DH_flav_C; 1; .
TIGRFAMsTIGR01816; SdhA_forward; 1; .
TIGRFAMsTIGR01812; SdhA_frdA_Gneg; 1; .
PROSITEPS00504; FRD_SDH_FAD_BINDING; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server