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Searching in 'World-2DPAGE Repository [0019]' for entry matching: Q8R4C1




World-2DPAGE Repository (0019):  Q8R4C1


Q8R4C1


General information about the entry
View entry in simple text format
Entry nameAT2C2_RAT
Primary accession numberQ8R4C1
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Calcium-transporting ATPase type 2C member 2; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;.
Gene nameName=Atp2c2
Synonyms=Spca2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info
 
HIPP_SYNAP

MAP LOCATIONS:
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]
pI=5.83; Mw=104094  [identification data]

IDENTIFICATION: SPOT 39: Peptides number=9. SeqCov=6.5%. MOWSE score=3.39E+2 [1]
SPOT 331: Peptides number=10. SeqCov=6.5%. MOWSE score=1.04E+2 [1]; SPOT 452: Peptides number=8. SeqCov=6.5%. MOWSE score=2.03E+2 [1]; SPOT 604: Peptides number=9. SeqCov=6.6%. MOWSE score=3.02E+1 [1]; SPOT 888: Peptides number=9. SeqCov=6.5%. MOWSE score=2.04E+2 [1]; SPOT 1052: Peptides number=10. SeqCov=5.5%. MOWSE score=2.73E+3 [1]; SPOT 1054: Peptides number=9. SeqCov=5.5%. MOWSE score=4.14E+2 [1]; SPOT 1069: Peptides number=9. SeqCov=6.5%. MOWSE score=2.04E+2 [1]; SPOT 1071: Peptides number=9. SeqCov=4.9%. MOWSE score=4.40E+2 [1]; SPOT 1125: Peptides number=9. SeqCov=9%. MOWSE score=1.75E+1 [1]; SPOT 1159: Peptides number=9. SeqCov=6.5%. MOWSE score=2.03E+2 [1].
MAPPING (identification):
SPOT 39: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 331: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 452: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 604: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 888: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1052: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1054: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1069: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1071: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1125: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 1159: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtQ8R4C1; AT2C2_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameAT2C2_RAT
Primary accession numberQ8R4C1
Sequence was last modified on June 1, 2002 (version 1)
Annotations were last modified on November 16, 2011 (version 68)
Name and origin of the protein
DescriptionRecName: Full=Calcium-transporting ATPase type 2C member 2; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;
Gene nameName=Atp2c2
Synonyms=Spca2
Encoded onName=Atp2c2; Synonyms=Spca2
KeywordsATP-binding; Calcium; Calcium transport; Complete proteome; Hydrolase; Ion transport; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF484685; AAL91565.1; -; mRNA
IPIIPI00200561; -; .
RefSeqNP_604457.1; NM_134462.1; .
UniGeneRn.163411; -; .
HSSPP04191; 1WPG; .
ProteinModelPortalQ8R4C1; -; .
PRIDEQ8R4C1; -; .
GeneID171496; -; .
KEGGrno:171496; -; .
CTD9914; -; .
RGD620647; Atp2c2; .
HOVERGENHBG106478; -; .
PhylomeDBQ8R4C1; -; .
NextBio622447; -; .
GenevestigatorQ8R4C1; -; .
GOGO:0016021; C:integral to membrane; IEA:UniProtKB-KW; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0005388; F:calcium-transporting ATPase activity; IEA:EC; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0006754; P:ATP biosynthetic process; IEA:InterPro; .
InterProIPR023306; ATPase_cation_domN; .
InterProIPR008250; ATPase_P-typ_ATPase-assoc-dom; .
InterProIPR006413; ATPase_P-typ_Ca-transp_PMR1; .
InterProIPR006068; ATPase_P-typ_cation-transptr_C; .
InterProIPR004014; ATPase_P-typ_cation-transptr_N; .
InterProIPR023300; ATPase_P-typ_cyto_domA; .
InterProIPR023299; ATPase_P-typ_cyto_domN; .
InterProIPR000695; ATPase_P-typ_H-transp; .
InterProIPR001757; ATPase_P-typ_ion-transptr; .
InterProIPR018303; ATPase_P-typ_P_site; .
InterProIPR023298; ATPase_P-typ_TM_dom; .
InterProIPR005834; Dehalogen-like_hydro; .
InterProIPR023214; HAD-like_dom; .
Gene3DG3DSA:2.70.150.10; ATPase_P-typ_cyto_domA; 2; .
Gene3DG3DSA:3.40.1110.10; ATPase_P-typ_cyto_domN; 1; .
Gene3DG3DSA:1.20.1110.10; ATPase_P-typ_TM_dom; 2; .
KOK01537; -; .
PfamPF00689; Cation_ATPase_C; 1; .
PfamPF00690; Cation_ATPase_N; 1; .
PfamPF00122; E1-E2_ATPase; 1; .
PfamPF00702; Hydrolase; 1; .
PRINTSPR00119; CATATPASE; .
PRINTSPR00120; HATPASE; .
SMARTSM00831; Cation_ATPase_N; 1; .
SUPFAMSSF81660; ATPase_cation_domN; 1; .
SUPFAMSSF56784; HAD-like_dom; 1; .
TIGRFAMsTIGR01522; ATPase-IIA2_Ca; 1; .
TIGRFAMsTIGR01494; ATPase_P-type; 2; .
PROSITEPS00154; ATPASE_E1_E2; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server