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Searching in 'World-2DPAGE Repository [0027]' for entry matching: Q99LB7

World-2DPAGE Repository (0027):  Q99LB7


General information about the entry
View entry in simple text format
Primary accession numberQ99LB7
integrated into World-2DPAGE Repository (0027) on September 30, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Sarcosine dehydrogenase, mitochondrial; Short=SarDH; EC=; Flags: Precursor;.
Gene nameName=Sardh
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
Blutke A., Block C., Berendt F., Herbach N., Kemter E., Amann K., Frolich T., Arnold G.J., Wanke R.
''Differential glomerular proteome analysis of two murine nephropathy models at onset of albuminuria''
Proteomics - Clinical Applications 5(6):375-381 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

GIPRDN_4-7 {glomerular protein lysates of a GIPRdn-tg animal}
Mus musculus (Mouse)
  map experimental info

pI=6.23; Mw=97000  [identification data]

SPOT 1: Avg ratio GIPRdn-tg vs. control=1.55 (p-value=0.0083) [1].

IDENTIFICATION: SPOT 1: SeqCov=11%. Mascot protein score=89 [1].
MAPPING (identification):
SPOT 1: Peptide mass fingerprinting [1].

Data from Dr. Andreas Blutke, Institute of Veterinary Pathology, University Munich, Germany
UniProtKB/Swiss-ProtQ99LB7; SARDH_MOUSE.
World-2DPAGE RepositoryQ99LB7; SARDH_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Primary accession numberQ99LB7
Sequence was last modified on June 1, 2001 (version 1)
Annotations were last modified on November 16, 2011 (version 74)
Name and origin of the protein
DescriptionRecName: Full=Sarcosine dehydrogenase, mitochondrial; Short=SarDH; EC=; Flags: Precursor;
Gene nameName=Sardh
Encoded onName=Sardh
KeywordsAcetylation; Complete proteome; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Phosphoprotein; Reference proteome; Transit peptide.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLBC003456; AAH03456.1; -; mRNA
IPIIPI00136213; -; .
RefSeqNP_619606.1; NM_138665.2; .
UniGeneMm.278467; -; .
ProteinModelPortalQ99LB7; -; .
SMRQ99LB7; 66-917; .
STRINGQ99LB7; -; .
PhosphoSiteQ99LB7; -; .
PRIDEQ99LB7; -; .
EnsemblENSMUST00000102886; ENSMUSP00000099950; ENSMUSG00000009614; .
GeneID192166; -; .
KEGGmmu:192166; -; .
CTD1757; -; .
MGIMGI:2183102; Sardh; .
GeneTreeENSGT00530000063120; -; .
HOGENOMHBG322775; -; .
HOVERGENHBG002326; -; .
InParanoidQ99LB7; -; .
OrthoDBEOG4XKV66; -; .
PhylomeDBQ99LB7; -; .
NextBio371164; -; .
ArrayExpressQ99LB7; -; .
BgeeQ99LB7; -; .
CleanExMM_SARDH; -; .
GenevestigatorQ99LB7; -; .
GermOnlineENSMUSG00000009614; Mus musculus; .
GOGO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell; .
GOGO:0004047; F:aminomethyltransferase activity; IEA:InterPro; .
GOGO:0008480; F:sarcosine dehydrogenase activity; IEA:EC; .
GOGO:0006546; P:glycine catabolic process; IEA:InterPro; .
InterProIPR006076; FAD-dep_OxRdtase; .
InterProIPR013977; GCV_T_C; .
InterProIPR006222; GCV_T_N; .
KOK00314; -; .
PfamPF01266; DAO; 1; .
PfamPF01571; GCV_T; 1; .
PfamPF08669; GCV_T_C; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server