World-2DPAGE Repository

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.

References

[1]	MAPPING ON GEL PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan] Maurya D.K., Sundaram C.S., Bhargava P. ''Proteome profile of the mature rat olfactory bulb'' Proteomics 9(1):2593-2599 (2009)

2D PAGE maps for identified proteins

How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb

map experimental info

OB21DSUB

MAP LOCATIONS:

SPOT 156:

pI=7.20; Mw=83000

[identification data]

MAPPING (identification):

SPOT 156: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India

Cross-references

UniProtKB/Swiss-Prot

Q9ER34; ACON_RAT.

2D PAGE maps for identified proteins
How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry name	ACON_RAT
Primary accession number	Q9ER34
Secondary accession number(s)	Q6P6V3
Sequence was last modified on	February 1, 2005 (version 2)
Annotations were last modified on	November 16, 2011 (version 77)
Name and origin of the protein
Description	RecName: Full=Aconitate hydratase, mitochondrial; Short=Aconitase; EC=4.2.1.3; AltName: Full=Citrate hydro-lyase; Flags: Precursor;
Gene name	Name=Aco2
Encoded on	Name=Aco2
Keywords	4Fe-4S; Acetylation; Complete proteome; Direct protein sequencing; Iron; Iron-sulfur; Isopeptide bond; Lyase; Metal-binding; Mitochondrion; Pyrrolidone carboxylic acid; Reference proteome; Transit peptide; Tricarboxylic acid cycle; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	AJ243266; CAC11018.1; -; mRNA
EMBL	BC061999; AAH61999.1; -; mRNA
IPI	IPI00421539; -; .
RefSeq	NP_077374.2; NM_024398.2; .
UniGene	Rn.43737; -; .
ProteinModelPortal	Q9ER34; -; .
SMR	Q9ER34; 29-780; .
IntAct	Q9ER34; 1; .
STRING	Q9ER34; -; .
PhosphoSite	Q9ER34; -; .
World-2DPAGE	0004:Q9ER34; -; .
PRIDE	Q9ER34; -; .
Ensembl	ENSRNOT00000038612; ENSRNOP00000029144; ENSRNOG00000024128; .
GeneID	79250; -; .
KEGG	rno:79250; -; .
NMPDR	fig\|10116.3.peg.27460; -; .
UCSC	NM_024398; rat; .
CTD	50; -; .
RGD	621360; Aco2; .
eggNOG	roNOG05633; -; .
GeneTree	ENSGT00530000063060; -; .
HOVERGEN	HBG000248; -; .
InParanoid	Q9ER34; -; .
OMA	KHGIRWV; -; .
OrthoDB	EOG4BCDM9; -; .
PhylomeDB	Q9ER34; -; .
NextBio	614724; -; .
ArrayExpress	Q9ER34; -; .
Genevestigator	Q9ER34; -; .
GermOnline	ENSRNOG00000024128; Rattus norvegicus; .
GO	GO:0005739; C:mitochondrion; IDA:RGD; .
GO	GO:0051538; F:3 iron; 4 sulfur cluster binding; IDA:RGD
GO	GO:0051539; F:4 iron; 4 sulfur cluster binding; IDA:RGD
GO	GO:0003994; F:aconitate hydratase activity; IDA:RGD; .
GO	GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GO	GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC; .
GO	GO:0005515; F:protein binding; IPI:RGD; .
GO	GO:0006101; P:citrate metabolic process; IDA:RGD; .
GO	GO:0006102; P:isocitrate metabolic process; IDA:RGD; .
GO	GO:0006099; P:tricarboxylic acid cycle; IDA:RGD; .
InterPro	IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3; .
InterPro	IPR015937; Acoase/IPM_deHydtase; .
InterPro	IPR001030; Acoase/IPM_deHydtase_lsu_aba; .
InterPro	IPR015928; Aconitase/3IPM_dehydase_swvl; .
InterPro	IPR015932; Aconitase/IPMdHydase_lsu_aba_2; .
InterPro	IPR018136; Aconitase_4Fe-4S_BS; .
InterPro	IPR006248; Aconitase_mito-like; .
InterPro	IPR000573; AconitaseA/IPMdHydase_ssu_swvl; .
Gene3D	G3DSA:3.30.499.10; Acnase/IPM_dHydase_lsu_aba_1/3; 2; .
Gene3D	G3DSA:3.20.19.10; Aconitase/3IPM_dehydase_swvl; 1; .
Gene3D	G3DSA:3.40.1060.10; Aconitase/IPMdHydase_lsu_aba_2; 1; .
KO	K01681; -; .
PANTHER	PTHR11670; Aconitase-like_core; 1; .
PANTHER	PTHR11670:SF5; Aconitase_mito; 1; .
Pfam	PF00330; Aconitase; 1; .
Pfam	PF00694; Aconitase_C; 1; .
PRINTS	PR00415; ACONITASE; .
SUPFAM	SSF52016; Aconitase/3IPM_dehydase_swvl; 1; .
SUPFAM	SSF53732; Aconitase_N; 1; .
TIGRFAMs	TIGR01340; Aconitase_mito; 1; .
PROSITE	PS00450; ACONITASE_1; 1; .
PROSITE	PS01244; ACONITASE_2; 1; .

World-2DPAGE Repository (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server

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