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Searching in 'World-2DPAGE Repository [0004]' for entry matching: RHOA_RAT

World-2DPAGE Repository (0004):  RHOA_RAT


General information about the entry
View entry in simple text format
Entry nameRHOA_RAT
Primary accession numberP61589
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Transforming protein RhoA; Flags: Precursor;.
Gene nameName=Rhoa
Synonyms=Arha, Arha2
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
  map experimental info

pI=5.97; Mw=24000  [identification data]

MAPPING (identification):
SPOT 659: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
UniProtKB/Swiss-ProtP61589; RHOA_RAT.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameRHOA_RAT
Primary accession numberP61589
Sequence was last modified on May 24, 2004 (version 1)
Annotations were last modified on December 14, 2011 (version 84)
Name and origin of the protein
DescriptionRecName: Full=Transforming protein RhoA; Flags: Precursor;
Gene nameName=Rhoa
Synonyms=Arha, Arha2
Encoded onName=Rhoa; Synonyms=Arha, Arha2
KeywordsCell cycle; Cell division; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Phosphoprotein; Prenylation; Proto-oncogene; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAY026068; AAK11717.1; -; mRNA
EMBLAY026069; AAK11718.1; -; mRNA
EMBLBC061732; AAH61732.1; -; mRNA
IPIIPI00201699; -; .
RefSeqNP_476473.1; NM_057132.3; .
UniGeneRn.107401; -; .
ProteinModelPortalP61589; -; .
SMRP61589; 2-181; .
IntActP61589; 1; .
MINTMINT-4542785; -; .
STRINGP61589; -; .
PhosphoSiteP61589; -; .
World-2DPAGE0004:P61589; -; .
PRIDEP61589; -; .
GeneID117273; -; .
KEGGrno:117273; -; .
UCSCAY026068; rat; .
CTD387; -; .
RGD619921; Rhoa; .
GeneTreeENSGT00550000074256; -; .
HOVERGENHBG009351; -; .
InParanoidP61589; -; .
OrthoDBEOG4G4GRD; -; .
PhylomeDBP61589; -; .
NextBio620199; -; .
ArrayExpressP61589; -; .
GenevestigatorP61589; -; .
GermOnlineENSRNOG00000012630; Rattus norvegicus; .
GOGO:0030424; C:axon; IDA:RGD; .
GOGO:0005938; C:cell cortex; ISS:UniProtKB; .
GOGO:0032154; C:cleavage furrow; ISS:UniProtKB; .
GOGO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; .
GOGO:0005624; C:membrane fraction; IDA:RGD; .
GOGO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0005525; F:GTP binding; TAS:RGD; .
GOGO:0003924; F:GTPase activity; NAS:RGD; .
GOGO:0019904; F:protein domain specific binding; IPI:RGD; .
GOGO:0030036; P:actin cytoskeleton organization; TAS:RGD; .
GOGO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IMP:RGD; .
GOGO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IMP:RGD; .
GOGO:0045665; P:negative regulation of neuron differentiation; IMP:RGD; .
GOGO:0048812; P:neuron projection morphogenesis; IEP:RGD; .
GOGO:0030838; P:positive regulation of actin filament polymerization; IMP:RGD; .
GOGO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:RGD; .
GOGO:0045785; P:positive regulation of cell adhesion; IEP:RGD; .
GOGO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB; .
GOGO:0030307; P:positive regulation of cell growth; IMP:RGD; .
GOGO:0030335; P:positive regulation of cell migration; IEP:RGD; .
GOGO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB; .
GOGO:0043525; P:positive regulation of neuron apoptosis; IMP:RGD; .
GOGO:0045727; P:positive regulation of translation; IEP:RGD; .
GOGO:0045907; P:positive regulation of vasoconstriction; IEP:RGD; .
GOGO:0050773; P:regulation of dendrite development; IMP:RGD; .
GOGO:0043200; P:response to amino acid stimulus; IEP:RGD; .
GOGO:0042493; P:response to drug; IDA:RGD; .
GOGO:0045471; P:response to ethanol; IEP:RGD; .
GOGO:0051384; P:response to glucocorticoid stimulus; IEP:RGD; .
GOGO:0009749; P:response to glucose stimulus; IEP:RGD; .
GOGO:0001666; P:response to hypoxia; IEP:RGD; .
GOGO:0009612; P:response to mechanical stimulus; IEP:RGD; .
GOGO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro; .
GOGO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD; .
InterProIPR005225; Small_GTP-bd_dom; .
InterProIPR001806; Small_GTPase; .
InterProIPR003578; Small_GTPase_Rho; .
KOK04513; -; .
PfamPF00071; Ras; 1; .
SMARTSM00174; RHO; 1; .
TIGRFAMsTIGR00231; Small_GTP; 1; .
PROSITEPS51420; RHO; 1; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server