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Searching in 'World-2DPAGE Repository [0022]' for entry matching: SPA3K_RAT




World-2DPAGE Repository (0022):  SPA3K_RAT


SPA3K_RAT


General information about the entry
View entry in simple text format
Entry nameSPA3K_RAT
Primary accession numberP05545
integrated into World-2DPAGE Repository (0022) on May 7, 2010 (release 1)
2D Annotations were last modified onJune 22, 2011 (version 2)
General Annotations were last modified on November 24, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serine protease inhibitor A3K; Short=Serpin A3K; AltName: Full=CPI-21; AltName: Full=Contrapsin-like protease inhibitor 1; AltName: Full=GHR-P63; AltName: Full=Growth hormone-regulated proteinase inhibitor; AltName: Full=Kallikrein-binding protein; Short=KBP; AltName: Full=SPI-2.3; AltName: Full=Serine protease inhibitor 2; Short=SPI-2; AltName: Full=Thyroid hormone-regulated protein; Flags: Precursor;.
Gene nameName=Serpina3k
Synonyms=Spin2b
Annotated speciesRattus [TaxID: 10114]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000593;
Burniston J.G., Kenyani J., Wastling J.M., Burant C.F., Qi N.R., Koch L.G., Britton S.L.
''Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity''
Proteomics 11(16):3369-3379 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

HCR_LCR_HEART {HCR LCR Cardiac Map}
Rattus
Tissue: Heart
HCR_LCR_HEART
  map experimental info
 
HCR_LCR_HEART

MAP LOCATIONS:
pI=5.31; Mw=46760  [identification data]
pI=5.31; Mw=46760  [identification data]

IDENTIFICATION: SPOT 562: SeqCov=16.3%. Peptides MS=7/20. Mascot PMF Score=47 [1]
SPOT 608: SeqCov=19.2%. Peptides MS=9/20. Mascot PMF Score=69 [1].
PEPTIDE EVIDENCE: SPOT 562: 303-IISELR-308 (9) / 188-IAELFSELDER-198 (97) / 312-FSISTDYNLEEVLPELGIR-330 (110) [1]
SPOT 608: 303-IISELR-308 (13) / 188-IAELFSELDER-198 (91) / 312-FSISTDYNLEEVLPELGIR-330 (68) [1].
MAPPING (identification):
SPOT 562: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 608: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Jatin Burniston, Liverpool John Moores University, UK
Cross-references
UniProtKB/Swiss-ProtP05545; SPA3K_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameSPA3K_RAT
Primary accession numberP05545
Secondary accession number(s) P14281 Q64254 Q6P6G8
Sequence was last modified on April 1, 1993 (version 3)
Annotations were last modified on November 16, 2011 (version 99)
Name and origin of the protein
DescriptionRecName: Full=Serine protease inhibitor A3K; Short=Serpin A3K; AltName: Full=CPI-21; AltName: Full=Contrapsin-like protease inhibitor 1; AltName: Full=GHR-P63; AltName: Full=Growth hormone-regulated proteinase inhibitor; AltName: Full=Kallikrein-binding protein; Short=KBP; AltName: Full=SPI-2.3; AltName: Full=Serine protease inhibitor 2; Short=SPI-2; AltName: Full=Thyroid hormone-regulated protein; Flags: Precursor;
Gene nameName=Serpina3k
Synonyms=Spin2b
Encoded onName=Serpina3k; Synonyms=Spin2b
KeywordsComplete proteome; Direct protein sequencing; Glycoprotein; Polymorphism; Protease inhibitor; Reference proteome; Secreted; Serine protease inhibitor; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX05348; CAA28958.1; -; mRNA
EMBLM15916; AAA42173.1; -; mRNA
EMBLX16358; CAA34407.1; ALT_INIT; mRNA
EMBLX16362; CAA34409.1; ALT_INIT; Genomic_DNA
EMBLD00751; BAA00648.1; -; mRNA
EMBLM67496; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLBC062236; AAH62236.2; ALT_INIT; mRNA
IPIIPI00200593; -; .
PIRA29035; A29035; .
PIRB29131; B29131; .
RefSeqNP_036789.2; NM_012657.2; .
UniGeneRn.91257; -; .
ProteinModelPortalP05545; -; .
SMRP05545; 45-415; .
STRINGP05545; -; .
MEROPSI04.051; -; .
PhosphoSiteP05545; -; .
PRIDEP05545; -; .
EnsemblENSRNOT00000013896; ENSRNOP00000013896; ENSRNOG00000010410; .
GeneID24794; -; .
KEGGrno:24794; -; .
UCSCBC062236; rat; .
CTD20714; -; .
RGD3746; Serpina3k; .
eggNOGroNOG14752; -; .
GeneTreeENSGT00560000076583; -; .
HOVERGENHBG005957; -; .
InParanoidP05545; -; .
OrthoDBEOG4FFD1T; -; .
ArrayExpressP05545; -; .
GenevestigatorP05545; -; .
GermOnlineENSRNOG00000010410; Rattus norvegicus; .
GOGO:0005576; C:extracellular region; IBA:RefGenome; .
GOGO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome; .
GOGO:0030162; P:regulation of proteolysis; IBA:RefGenome; .
InterProIPR000215; Protease_inhib_I4_serpin; .
InterProIPR023795; Protease_inhib_I4_serpin_CS; .
InterProIPR023796; Sepin_dom; .
KOK04525; -; .
PANTHERPTHR11461; Prot_inh_serpin; 1; .
PfamPF00079; Serpin; 1; .
SMARTSM00093; SERPIN; 1; .
SUPFAMSSF56574; Prot_inh_serpin; 1; .
PROSITEPS00284; SERPIN; 1; .



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