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Searching in 'World-2DPAGE Repository [0030]' for entry matching: SRSF1_MOUSE

World-2DPAGE Repository (0030):  SRSF1_MOUSE


General information about the entry
View entry in simple text format
Entry nameSRSF1_MOUSE
Primary accession numberQ6PDM2
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Serine/arginine-rich splicing factor 1; AltName: Full=ASF/SF2; AltName: Full=Pre-mRNA-splicing factor SRp30a; AltName: Full=Splicing factor, arginine/serine-rich 1;.
Gene nameName=Srsf1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
  map experimental info

pI=5.05; Mw=40100  [identification data]

IDENTIFICATION: SPOT 1701: Mascot protein score=83. Number of peptides=6 [1].
MAPPING (identification):
SPOT 1701: Tandem mass spectrometry [1].

Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
UniProtKB/Swiss-ProtQ6PDM2; SRSF1_MOUSE.
World-2DPAGE RepositoryQ6PDM2; SRSF1_MOUSE.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameSRSF1_MOUSE
Primary accession numberQ6PDM2
Secondary accession number(s) B2KGJ5 Q3UCH2 Q5SXC5 Q8BJV3 Q8C1H9
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 94)
Name and origin of the protein
DescriptionRecName: Full=Serine/arginine-rich splicing factor 1; AltName: Full=ASF/SF2; AltName: Full=Pre-mRNA-splicing factor SRp30a; AltName: Full=Splicing factor, arginine/serine-rich 1;
Gene nameName=Srsf1
Encoded onName=Srsf1; Synonyms=Sfrs1
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding; Spliceosome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAK018176; BAC25546.1; -; mRNA
EMBLAK078715; BAC37367.1; -; mRNA
EMBLAK150535; BAE29641.1; -; mRNA
EMBLAL593853; CAI24416.1; -; Genomic_DNA
EMBLCU406964; CAQ51705.1; -; Genomic_DNA
EMBLBC046773; AAH46773.1; -; mRNA
EMBLBC058627; AAH58627.1; -; mRNA
IPIIPI00420807; -; .
IPIIPI00457656; -; .
IPIIPI00515505; -; .
PIRS26404; S26404; .
RefSeqNP_001071635.1; NM_001078167.1; .
RefSeqNP_775550.2; NM_173374.3; .
UniGeneMm.391719; -; .
PDB1X4C; NMR; -; A=113-207
PDBsum1X4C; -; .
ProteinModelPortalQ6PDM2; -; .
SMRQ6PDM2; 6-102; 107-197; .
DIPDIP-48723N; -; .
IntActQ6PDM2; 1; .
PhosphoSiteQ6PDM2; -; .
EnsemblENSMUST00000079866; ENSMUSP00000133517; ENSMUSG00000018379; .
EnsemblENSMUST00000139129; ENSMUSP00000120595; ENSMUSG00000018379; .
GeneID110809; -; .
KEGGmmu:110809; -; .
UCSCuc007kvc.1; mouse; .
UCSCuc007kvd.1; mouse; .
CTD6426; -; .
MGIMGI:98283; Srsf1; .
eggNOGroNOG04175; -; .
GeneTreeENSGT00560000076885; -; .
HOGENOMHBG756718; -; .
HOVERGENHBG002295; -; .
InParanoidQ6PDM2; -; .
PhylomeDBQ6PDM2; -; .
NextBio461971; -; .
ArrayExpressQ6PDM2; -; .
BgeeQ6PDM2; -; .
CleanExMM_SFRS1; -; .
GenevestigatorQ6PDM2; -; .
GermOnlineENSMUSG00000018379; Mus musculus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell; .
GOGO:0000166; F:nucleotide binding; IEA:InterPro; .
GOGO:0003723; F:RNA binding; ISS:UniProtKB; .
GOGO:0050733; F:RS domain binding; IPI:MGI; .
GOGO:0001701; P:in utero embryonic development; IMP:MGI; .
GOGO:0000395; P:nuclear mRNA 5'-splice site recognition; ISS:UniProtKB; .
InterProIPR012677; Nucleotide-bd_a/b_plait; .
InterProIPR000504; RRM_dom; .
Gene3DG3DSA:; a_b_plait_nuc_bd; 2; .
KOK12890; -; .
PfamPF00076; RRM_1; 2; .
SMARTSM00360; RRM; 2; .
PROSITEPS50102; RRM; 2; .

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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server