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Searching in 'World-2DPAGE Repository [0019]' for entry matching: TBB3_RAT




World-2DPAGE Repository (0019):  TBB3_RAT

TBB3_RAT


General information about the entry
View entry in simple text format
Entry nameTBB3_RAT
Primary accession numberQ4QRB4
integrated into World-2DPAGE Repository (0019) on December 9, 2009 (release 1)
2D Annotations were last modified onMay 30, 2011 (version 2)
General Annotations were last modified on January 13, 2012 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Tubulin beta-3 chain; AltName: Full=Neuron-specific class III beta-tubulin;.
Gene nameName=Tubb3
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1111/j.1471-4159.2010.06719.x;
VanGuilder H.D., Yan H., Farley J.A., Sonntag W.E., Freeman W.M.
''Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome''
J of Neurochemistry 113(6):1577-1588 (2010)
2D PAGE maps for identified proteins
How to interpret a protein

HIPP_SYNAP {Rat hippocampal synaptoproteome}
Rattus norvegicus (Rat)
Tissue: Hippocampus
HIPP_SYNAP
  map experimental info 		 
HIPP_SYNAP

MAP LOCATIONS:
pI=4.79; Mw=50387  [identification data]

IDENTIFICATION: SPOT 923: Peptides number=3. SeqCov=11.3%. MOWSE score=5.39E+3 [1].
MAPPING (identification):
SPOT 923: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Willard Freeman, Penn State College of Medicine, USA
Cross-references
UniProtKB/Swiss-ProtQ4QRB4; TBB3_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameTBB3_RAT
Primary accession numberQ4QRB4
Secondary accession number(s) Q8K5B6
Sequence was last modified on July 19, 2005 (version 1)
Annotations were last modified on November 16, 2011 (version 60)
Name and origin of the protein
DescriptionRecName: Full=Tubulin beta-3 chain; AltName: Full=Neuron-specific class III beta-tubulin;
Gene nameName=Tubb3
Encoded onName=Tubb3
KeywordsAcetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF459021; AAM28438.1; -; mRNA
EMBLBC097281; AAH97281.1; -; mRNA
IPIIPI00362160; -; .
RefSeqNP_640347.2; NM_139254.2; .
UniGeneRn.43958; -; .
ProteinModelPortalQ4QRB4; -; .
SMRQ4QRB4; 2-427; .
IntActQ4QRB4; 2; .
MINTMINT-2982718; -; .
STRINGQ4QRB4; -; .
PhosphoSiteQ4QRB4; -; .
PRIDEQ4QRB4; -; .
EnsemblENSRNOT00000023452; ENSRNOP00000023452; ENSRNOG00000017209; .
GeneID246118; -; .
KEGGrno:246118; -; .
CTD10381; -; .
RGD628595; Tubb3; .
eggNOGmaNOG13588; -; .
HOVERGENHBG000089; -; .
InParanoidQ4QRB4; -; .
OMAVIDVLTC; -; .
OrthoDBEOG4W6NW0; -; .
PhylomeDBQ4QRB4; -; .
ReactomeREACT_115492; Developmental Biology; .
NextBio623383; -; .
ArrayExpressQ4QRB4; -; .
GenevestigatorQ4QRB4; -; .
GermOnlineENSRNOG00000017209; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-KW; .
GOGO:0005874; C:microtubule; IEA:UniProtKB-KW; .
GOGO:0005525; F:GTP binding; IEA:UniProtKB-KW; .
GOGO:0003924; F:GTPase activity; IEA:InterPro; .
GOGO:0042277; F:peptide binding; IPI:RGD; .
GOGO:0005200; F:structural constituent of cytoskeleton; NAS:RGD; .
GOGO:0007411; P:axon guidance; ISS:UniProtKB; .
GOGO:0007018; P:microtubule-based movement; IEA:InterPro; .
GOGO:0007067; P:mitosis; IMP:RGD; .
GOGO:0051258; P:protein polymerization; IEA:InterPro; .
InterProIPR013838; Beta-tubulin_BS; .
InterProIPR002453; Beta_tubulin; .
InterProIPR008280; Tub_FtsZ_C; .
InterProIPR000217; Tubulin; .
InterProIPR018316; Tubulin/FtsZ_2-layer-sand-dom; .
InterProIPR023123; Tubulin_C; .
InterProIPR017975; Tubulin_CS; .
InterProIPR003008; Tubulin_FtsZ_GTPase; .
Gene3DG3DSA:3.30.1330.20; Tubulin/FtsZ_2-layer-sand-dom; 1; .
Gene3DG3DSA:1.10.287.600; Tubulin_C; 1; .
Gene3DG3DSA:3.40.50.1440; Tubulin_FtsZ; 1; .
KOK07375; -; .
PANTHERPTHR11588; Tubulin; 1; .
PfamPF00091; Tubulin; 1; .
PfamPF03953; Tubulin_C; 1; .
PRINTSPR01163; BETATUBULIN; .
PRINTSPR01161; TUBULIN; .
SMARTSM00864; Tubulin; 1; .
SMARTSM00865; Tubulin_C; 1; .
SUPFAMSSF55307; Tub_FtsZ_C; 1; .
SUPFAMSSF52490; Tubulin_FtsZ; 1; .
PROSITEPS00227; TUBULIN; 1; .
PROSITEPS00228; TUBULIN_B_AUTOREG; 1; .


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