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World-2DPAGE Repository  Search by  [accession number]  [description, ID or gene]  [author names]  [spot ID / serial number]  [identification methods]  [pI / Mw range]  [combined fields]  Maps  [experimental info]  [protein list]  [graphical interface]      Databases 0001 0002 0003 0004 0005 0006 0007 0008 0009 0010 0011 0012 0014 0017 0018 0019 0020 0021 0022 0023 0024 0026 0027 0029 0030 0031 0032 0034 0035 0036 0037 0038 0039 0040 0042 0043 0044 0046 0047 0050 0051 0053 0054 0056 0059 0061 0062 0063 0066 0068 0069 0076 0077 0080 0084 0085 0088 use 'Ctrl' to select several databases Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal Exclude local DBs has only effect if a remote interface is selected

Searching in 'World-2DPAGE Repository [0030]' for entry matching: THOP1_RAT World-2DPAGE Repository (0030):  THOP1_RAT THOP1_RAT General information about the entry View entry in simple text format Entry name THOP1_RAT Primary accession number P24155 integrated into World-2DPAGE Repository (0030) on  November 9, 2010 (release 1) 2D Annotations were last modified on June 21, 2011 (version 2) General Annotations were last modified on  November 23, 2011 (version 2) Name and origin of the protein Description RecName: Full=Thimet oligopeptidase; EC=3.4.24.15; AltName: Full=Endo-oligopeptidase A; AltName: Full=Endopeptidase 24.15; AltName: Full=PZ-peptidase; AltName: Full=Soluble metallo-endopeptidase;. Gene name Name=Thop1 Annotated species Rattus norvegicus (Rat) [TaxID: 10116] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus. References [1]   2D-PAGE GEL CHARACTERIZATION DOI=10.1002/pmic.201000006; D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C. ''Two-dimensional gel proteome reference map of INS-1E cells'' Proteomics 11(7):1365-1369 (2011) 2D PAGE maps for identified proteins How to interpret a protein RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7} Rattus norvegicus (Rat)   map experimental info   RAT_INS1E_4-7 MAP LOCATIONS: SPOT 474: pI=5.83; Mw=83246   [identification data] IDENTIFICATION: SPOT 474: Mascot protein score=37. Number of peptides=2 [1]. MAPPING (identification): SPOT 474: Tandem mass spectrometry [1]. Copyright Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium Cross-references UniProtKB/Swiss-Prot P24155; THOP1_RAT. World-2DPAGE Repository P24155; THOP1_RAT. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_11 Entry name THOP1_RAT Primary accession number P24155 Secondary accession number(s) Q66HS4 Sequence was last modified on  February 26, 2008 (version 4) Annotations were last modified on  November 16, 2011 (version 98) Name and origin of the protein Description RecName: Full=Thimet oligopeptidase; EC=3.4.24.15; AltName: Full=Endo-oligopeptidase A; AltName: Full=Endopeptidase 24.15; AltName: Full=PZ-peptidase; AltName: Full=Soluble metallo-endopeptidase; Gene name Name=Thop1 Encoded on Name=Thop1 Keywords Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Metal-binding; Metalloprotease; Phosphoprotein; Protease; Reference proteome; Zinc. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M61142; AAA41586.1; -; mRNA EMBL BC081706; AAH81706.1; -; mRNA IPI IPI00211777; -; . PIR S38760; HYRTTH; . RefSeq NP_742072.2; NM_172075.2; . UniGene Rn.9490; -; . ProteinModelPortal P24155; -; . SMR P24155; 24-677; . STRING P24155; -; . MEROPS M03.001; -; . PhosphoSite P24155; -; . PRIDE P24155; -; . Ensembl ENSRNOT00000027045; ENSRNOP00000027045; ENSRNOG00000019924; . GeneID 64517; -; . KEGG rno:64517; -; . UCSC BC081706; rat; . CTD 7064; -; . RGD 68330; Thop1; . eggNOG maNOG11722; -; . GeneTree ENSGT00550000074738; -; . HOVERGEN HBG000238; -; . InParanoid P24155; -; . OMA EQTKCVY; -; . OrthoDB EOG4CG07P; -; . PhylomeDB P24155; -; . BRENDA 3.4.24.15; 5301; . NextBio 613318; -; . ArrayExpress P24155; -; . Genevestigator P24155; -; . GermOnline ENSRNOG00000019924; Rattus norvegicus; . GO GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; . GO GO:0005625; C:soluble fraction; IDA:RGD; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0004222; F:metalloendopeptidase activity; TAS:RGD; . GO GO:0042277; F:peptide binding; IDA:RGD; . GO GO:0006508; P:proteolysis; TAS:RGD; . InterPro IPR024079; MetalloPept_cat_dom; . InterPro IPR024077; Neurolysin/TOP_dom2; . InterPro IPR024080; Neurolysin/TOP_N; . InterPro IPR001567; Pept_M3A_M3B; . Gene3D G3DSA:1.10.1370.10; G3DSA:1.10.1370.10; 2; . Gene3D G3DSA:1.20.1050.40; G3DSA:1.20.1050.40; 1; . Gene3D G3DSA:3.40.390.10; G3DSA:3.40.390.10; 1; . KO K01392; -; . Pfam PF01432; Peptidase_M3; 1; . PROSITE PS00142; ZINC_PROTEASE; 1; . World-2DPAGE Repository (search AC)