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Searching in 'World-2DPAGE Repository [0030]' for entry matching: THOP1_RAT




World-2DPAGE Repository (0030):  THOP1_RAT

THOP1_RAT


General information about the entry
View entry in simple text format
Entry nameTHOP1_RAT
Primary accession numberP24155
integrated into World-2DPAGE Repository (0030) on November 9, 2010 (release 1)
2D Annotations were last modified onJune 21, 2011 (version 2)
General Annotations were last modified on November 23, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Thimet oligopeptidase; EC=3.4.24.15; AltName: Full=Endo-oligopeptidase A; AltName: Full=Endopeptidase 24.15; AltName: Full=PZ-peptidase; AltName: Full=Soluble metallo-endopeptidase;.
Gene nameName=Thop1
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   2D-PAGE GEL CHARACTERIZATION
DOI=10.1002/pmic.201000006;
D'Hertog W., Maris M., Thorrez L., Waelkens E., Overbergh L., Mathieu C.
''Two-dimensional gel proteome reference map of INS-1E cells''
Proteomics 11(7):1365-1369 (2011)
2D PAGE maps for identified proteins
How to interpret a protein

RAT_INS1E_4-7 {INS-1E cell line, a model rat cell line for pancreatic beta cells, PH4-7}
Rattus norvegicus (Rat)
RAT_INS1E_4-7
  map experimental info 		 
RAT_INS1E_4-7

MAP LOCATIONS:
pI=5.83; Mw=83246  [identification data]

IDENTIFICATION: SPOT 474: Mascot protein score=37. Number of peptides=2 [1].
MAPPING (identification):
SPOT 474: Tandem mass spectrometry [1].

Copyright
Data from Dr. Wannes D'Hertog, Catholic University Leuven, Belgium
Cross-references
UniProtKB/Swiss-ProtP24155; THOP1_RAT.
World-2DPAGE RepositoryP24155; THOP1_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_11
Entry nameTHOP1_RAT
Primary accession numberP24155
Secondary accession number(s) Q66HS4
Sequence was last modified on February 26, 2008 (version 4)
Annotations were last modified on November 16, 2011 (version 98)
Name and origin of the protein
DescriptionRecName: Full=Thimet oligopeptidase; EC=3.4.24.15; AltName: Full=Endo-oligopeptidase A; AltName: Full=Endopeptidase 24.15; AltName: Full=PZ-peptidase; AltName: Full=Soluble metallo-endopeptidase;
Gene nameName=Thop1
Encoded onName=Thop1
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Metal-binding; Metalloprotease; Phosphoprotein; Protease; Reference proteome; Zinc.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM61142; AAA41586.1; -; mRNA
EMBLBC081706; AAH81706.1; -; mRNA
IPIIPI00211777; -; .
PIRS38760; HYRTTH; .
RefSeqNP_742072.2; NM_172075.2; .
UniGeneRn.9490; -; .
ProteinModelPortalP24155; -; .
SMRP24155; 24-677; .
STRINGP24155; -; .
MEROPSM03.001; -; .
PhosphoSiteP24155; -; .
PRIDEP24155; -; .
EnsemblENSRNOT00000027045; ENSRNOP00000027045; ENSRNOG00000019924; .
GeneID64517; -; .
KEGGrno:64517; -; .
UCSCBC081706; rat; .
CTD7064; -; .
RGD68330; Thop1; .
eggNOGmaNOG11722; -; .
GeneTreeENSGT00550000074738; -; .
HOVERGENHBG000238; -; .
InParanoidP24155; -; .
OMAEQTKCVY; -; .
OrthoDBEOG4CG07P; -; .
PhylomeDBP24155; -; .
BRENDA3.4.24.15; 5301; .
NextBio613318; -; .
ArrayExpressP24155; -; .
GenevestigatorP24155; -; .
GermOnlineENSRNOG00000019924; Rattus norvegicus; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0004222; F:metalloendopeptidase activity; TAS:RGD; .
GOGO:0042277; F:peptide binding; IDA:RGD; .
GOGO:0006508; P:proteolysis; TAS:RGD; .
InterProIPR024079; MetalloPept_cat_dom; .
InterProIPR024077; Neurolysin/TOP_dom2; .
InterProIPR024080; Neurolysin/TOP_N; .
InterProIPR001567; Pept_M3A_M3B; .
Gene3DG3DSA:1.10.1370.10; G3DSA:1.10.1370.10; 2; .
Gene3DG3DSA:1.20.1050.40; G3DSA:1.20.1050.40; 1; .
Gene3DG3DSA:3.40.390.10; G3DSA:3.40.390.10; 1; .
KOK01392; -; .
PfamPF01432; Peptidase_M3; 1; .
PROSITEPS00142; ZINC_PROTEASE; 1; .


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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server