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Searching in 'World-2DPAGE Repository [0004]' for entry matching: O88989




World-2DPAGE Repository (0004):  O88989


O88989


General information about the entry
View entry in simple text format
Entry nameMDHC_RAT
Primary accession numberO88989
integrated into World-2DPAGE Repository (0004) on October 13, 2008 (release 1)
2D Annotations were last modified onMay 18, 2011 (version 2)
General Annotations were last modified on December 22, 2011 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Malate dehydrogenase, cytoplasmic; EC=1.1.1.37; AltName: Full=Cytosolic malate dehydrogenase;.
Gene nameName=Mdh1
Synonyms=Mdh
Annotated speciesRattus norvegicus (Rat) [TaxID: 10116]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
References
[1]   MAPPING ON GEL
PubMed=19343716; DOI=10.1002/pmic.200800664; [NCBI, EBI, Israel, Japan]
Maurya D.K., Sundaram C.S., Bhargava P.
''Proteome profile of the mature rat olfactory bulb''
Proteomics 9(1):2593-2599 (2009)
2D PAGE maps for identified proteins
How to interpret a protein

OB21DSUB {2-DE gel for Olfactory bulb proteome}
Rattus norvegicus (Rat)
Tissue: Olfactory bulb
OB21DSUB
  map experimental info
 
OB21DSUB

MAP LOCATIONS:
pI=5.77; Mw=37000  [identification data]
pI=5.92; Mw=37000  [identification data]

MAPPING (identification):
SPOT 527: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1];
SPOT 528: Peptide mass fingerprinting [1]; Tandem mass spectrometry [1].

Copyright
Data from Dr. Purnima Bhargava, Centre for Cellular and Molecular Biology, India
Cross-references
UniProtKB/Swiss-ProtO88989; MDHC_RAT.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_12
Entry nameMDHC_RAT
Primary accession numberO88989
Secondary accession number(s) O88585 Q6PCV2
Sequence was last modified on January 23, 2007 (version 3)
Annotations were last modified on November 16, 2011 (version 84)
Name and origin of the protein
DescriptionRecName: Full=Malate dehydrogenase, cytoplasmic; EC=1.1.1.37; AltName: Full=Cytosolic malate dehydrogenase;
Gene nameName=Mdh1
Synonyms=Mdh
Encoded onName=Mdh1; Synonyms=Mdh
KeywordsAcetylation; Complete proteome; Cytoplasm; Direct protein sequencing; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Tricarboxylic acid cycle; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAF093773; AAC64180.1; -; mRNA
EMBLBC059124; AAH59124.1; -; mRNA
EMBLAF075574; AAC26799.1; -; mRNA
IPIIPI00198717; -; .
RefSeqNP_150238.1; NM_033235.1; .
UniGeneRn.13492; -; .
ProteinModelPortalO88989; -; .
SMRO88989; 2-334; .
IntActO88989; 1; .
STRINGO88989; -; .
PhosphoSiteO88989; -; .
World-2DPAGE0004:O88989; -; .
PRIDEO88989; -; .
EnsemblENSRNOT00000011429; ENSRNOP00000011429; ENSRNOG00000008103; .
GeneID24551; -; .
KEGGrno:24551; -; .
NMPDRfig|10116.3.peg.10844; -; .
UCSCNM_033235; rat; .
CTD4190; -; .
RGD3072; Mdh1; .
eggNOGroNOG11216; -; .
GeneTreeENSGT00530000063410; -; .
HOVERGENHBG006340; -; .
InParanoidO88989; -; .
OrthoDBEOG4CVG78; -; .
PhylomeDBO88989; -; .
NextBio603654; -; .
ArrayExpressO88989; -; .
GenevestigatorO88989; -; .
GermOnlineENSRNOG00000008103; Rattus norvegicus; .
GOGO:0005625; C:soluble fraction; IDA:RGD; .
GOGO:0030060; F:L-malate dehydrogenase activity; IDA:RGD; .
GOGO:0051287; F:NAD binding; IDA:RGD; .
GOGO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro; .
GOGO:0006108; P:malate metabolic process; IDA:RGD; .
GOGO:0006734; P:NADH metabolic process; IDA:RGD; .
GOGO:0006107; P:oxaloacetate metabolic process; IDA:RGD; .
GOGO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW; .
InterProIPR001557; L-lactate/malate_DH; .
InterProIPR022383; Lactate/malate_DH_C; .
InterProIPR001236; Lactate/malate_DH_N; .
InterProIPR015955; Lactate_DH/Glyco_Ohase_4_C; .
InterProIPR001252; Malate_DH_AS; .
InterProIPR011274; Malate_DH_NAD-dep_euk; .
InterProIPR010945; Malate_DH_type2; .
InterProIPR016040; NAD(P)-bd_dom; .
Gene3DG3DSA:3.90.110.10; lact_mal_DH; 1; .
Gene3DG3DSA:3.40.50.720; NAD(P)-bd; 1; .
KOK00025; -; .
PANTHERPTHR23382; MDH_SF1; 1; .
PfamPF02866; Ldh_1_C; 1; .
PfamPF00056; Ldh_1_N; 1; .
PIRSFPIRSF000102; Lac_mal_DH; 1; .
SUPFAMSSF56327; Lactate_DH/Glyco_hydro_4_C; 1; .
TIGRFAMsTIGR01759; MalateDH-SF1; 1; .
TIGRFAMsTIGR01758; MDH_euk_cyt; 1; .
PROSITEPS00068; MDH; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server