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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: O15160 SWISS-2DPAGE:  O15160 O15160 General information about the entry View entry in simple text format Entry name RPAC1_HUMAN Primary accession number O15160 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on March 31, 2004 (version 2) General Annotations were last modified on  May 19, 2011 (version 7) Name and origin of the protein Description RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1; Short=DNA-directed RNA polymerase I subunit C; Short=RNA polymerases I and III subunit AC1; AltName: Full=AC40; AltName: Full=DNA-directed RNA polymerases I and III 40 kDa polypeptide; Short=RPA40; AltName: Full=RPA39; AltName: Full=RPC40;. Gene name Name=POLR1C Synonyms=POLR1E Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001V8V: Mw=42495   [identification data] BAND 1D-001V8X: Mw=41811   [identification data] MAPPING (identification): BAND 1D-001V8V: PEPTIDE MASS FINGERPRINTING [1]; Tandem mass spectrometry [1]. NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_2D_HUMAN MAP LOCATIONS: SPOT 2D-001VOK: pI=5.50; Mw=42256   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references REPRODUCTION-2DPAGE IPI00217386; IPI00217386. UniProtKB/Swiss-Prot O15160; RPAC1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name RPAC1_HUMAN Primary accession number O15160 Secondary accession number(s) O75395 Q5JTE3 Sequence was last modified on  January 1, 1998 (version 1) Annotations were last modified on  October 19, 2011 (version 122) Name and origin of the protein Description RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1; Short=DNA-directed RNA polymerase I subunit C; Short=RNA polymerases I and III subunit AC1; AltName: Full=AC40; AltName: Full=DNA-directed RNA polymerases I and III 40 kDa polypeptide; Short=RPA40; AltName: Full=RPA39; AltName: Full=RPC40; Gene name Name=POLR1C Synonyms=POLR1E Encoded on Name=POLR1C; Synonyms=POLR1E Keywords Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Disease mutation; DNA-directed RNA polymerase; Nucleus; Phosphoprotein; Reference proteome; Transcription. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF008442; AAC14354.1; -; mRNA EMBL AF047441; AAC39892.1; -; mRNA EMBL AL355802; CAI42629.1; -; Genomic_DNA EMBL BC008863; AAH08863.1; -; mRNA IPI IPI00005179; -; . IPI IPI00217386; -; . RefSeq NP_976035.1; NM_203290.2; . UniGene Hs.727715; -; . ProteinModelPortal O15160; -; . SMR O15160; 46-346; . DIP DIP-27587N; -; . IntAct O15160; 7; . MINT MINT-1137932; -; . STRING O15160; -; . PhosphoSite O15160; -; . SWISS-2DPAGE O15160; -; . REPRODUCTION-2DPAGE IPI00217386; -; . PRIDE O15160; -; . Ensembl ENST00000372389; ENSP00000361465; ENSG00000171453; . GeneID 9533; -; . KEGG hsa:9533; -; . UCSC uc003ovn.1; human; . UCSC uc003ovo.1; human; . CTD 9533; -; . GeneCards GC06P043202; -; . HGNC HGNC:20194; POLR1C; . HPA HPA031010; -; . MIM 248390; phenotype; . MIM 610060; gene; . neXtProt NX_O15160; -; . Orphanet 861; Treacher-Collins syndrome; . PharmGKB PA134882004; -; . HOGENOM HBG539019; -; . HOVERGEN HBG017743; -; . InParanoid O15160; -; . OMA GKCQRFL; -; . PhylomeDB O15160; -; . Reactome REACT_1788; Transcription; . NextBio 35740; -; . ArrayExpress O15160; -; . Bgee O15160; -; . CleanEx HS_POLR1C; -; . CleanEx HS_POLR1E; -; . Genevestigator O15160; -; . GermOnline ENSG00000171453; Homo sapiens; . GO GO:0005736; C:DNA-directed RNA polymerase I complex; TAS:ProtInc; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0003677; F:DNA binding; IEA:InterPro; . GO GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc; . GO GO:0046983; F:protein dimerization activity; IEA:InterPro; . GO GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome; . GO GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome; . GO GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome; . InterPro IPR001514; DNA-dir_RNA_pol_30-40kDasu_CS; . InterPro IPR011261; DNA-dir_RNA_pol_dimersation; . InterPro IPR011262; DNA-dir_RNA_pol_insert; . InterPro IPR009025; DNA-dir_RNA_pol_RBP11-like; . InterPro IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3; . Gene3D G3DSA:2.170.120.12; RNAP_insert; 1; . Pfam PF01000; RNA_pol_A_bac; 1; . Pfam PF01193; RNA_pol_L; 1; . SMART SM00662; RPOLD; 1; . SUPFAM SSF56553; RNAP_insert; 1; . SUPFAM SSF55257; RNAP_RBP11-like; 1; . PROSITE PS00446; RNA_POL_D_30KD; 1; . SWISS-2DPAGE (search AC)