resource logo

SWISS-2DPAGE

Attention: World-2DPAGE is no longer maintained.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P02775




SWISS-2DPAGE:  P02775


P02775


General information about the entry
View entry in simple text format
Entry nameCXCL7_HUMAN
Primary accession numberP02775
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 15)
Name and origin of the protein
DescriptionRecName: Full=Platelet basic protein; Short=PBP; AltName: Full=C-X-C motif chemokine 7; AltName: Full=Leukocyte-derived growth factor; Short=LDGF; AltName: Full=Macrophage-derived growth factor; Short=MDGF; AltName: Full=Small-inducible cytokine B7; Contains: RecName: Full=Connective tissue-activating peptide III; Short=CTAP-III; AltName: Full=LA-PF4; AltName: Full=Low-affinity platelet factor IV; Contains: RecName: Full=TC-2; Contains: RecName: Full=Connective tissue-activating peptide III(1-81); Short=CTAP-III(1-81); Contains: RecName: Full=Beta-thromboglobulin; Short=Beta-TG; Contains: RecName: Full=Neutrophil-activating peptide 2(74); Short=NAP-2(74); Contains: RecName: Full=Neutrophil-activating peptide 2(73); Short=NAP-2(73); Contains: RecName: Full=Neutrophil-activating peptide 2; Short=NAP-2; Contains: RecName: Full=TC-1; Contains: RecName: Full=Neutrophil-activating peptide 2(1-66); Short=NAP-2(1-66); Contains: RecName: Full=Neutrophil-activating peptide 2(1-63); Short=NAP-2(1-63); Flags: Precursor;.
Gene nameName=PPBP
Synonyms=CTAP3, CXCL7, SCYB7, TGB1, THBGB1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=93092937; PubMed=1459097; [NCBI, Expasy, EBI, Israel, Japan]
Hughes G.J., Frutiger S., Paquet N., Ravier F., Pasquali C., Sanchez J.-C., James R.W., Tissot J.-D., Bjellqvist B., Hochstrasser D.F.
''''''Plasma protein map: an update by microsequencing'';'';''
Electrophoresis 13(1):707-714(1992)
Comments
  • SUBUNIT: HOMOTETRAMER
2D PAGE maps for identified proteins
How to interpret a protein

PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=7.27; Mw=8345

MAPPING (identification):
MICROSEQUENCING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP02775; CXCL7_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameCXCL7_HUMAN
Primary accession numberP02775
Secondary accession number(s) B2R5F3 Q6IBJ8
Sequence was last modified on November 1, 1991 (version 3)
Annotations were last modified on September 21, 2011 (version 136)
Name and origin of the protein
DescriptionRecName: Full=Platelet basic protein; Short=PBP; AltName: Full=C-X-C motif chemokine 7; AltName: Full=Leukocyte-derived growth factor; Short=LDGF; AltName: Full=Macrophage-derived growth factor; Short=MDGF; AltName: Full=Small-inducible cytokine B7; Contains: RecName: Full=Connective tissue-activating peptide III; Short=CTAP-III; AltName: Full=LA-PF4; AltName: Full=Low-affinity platelet factor IV; Contains: RecName: Full=TC-2; Contains: RecName: Full=Connective tissue-activating peptide III(1-81); Short=CTAP-III(1-81); Contains: RecName: Full=Beta-thromboglobulin; Short=Beta-TG; Contains: RecName: Full=Neutrophil-activating peptide 2(74); Short=NAP-2(74); Contains: RecName: Full=Neutrophil-activating peptide 2(73); Short=NAP-2(73); Contains: RecName: Full=Neutrophil-activating peptide 2; Short=NAP-2; Contains: RecName: Full=TC-1; Contains: RecName: Full=Neutrophil-activating peptide 2(1-66); Short=NAP-2(1-66); Contains: RecName: Full=Neutrophil-activating peptide 2(1-63); Short=NAP-2(1-63); Flags: Precursor;
Gene nameName=PPBP
Synonyms=CTAP3, CXCL7, SCYB7, TGB1, THBGB1
Encoded onName=PPBP; Synonyms=CTAP3, CXCL7, SCYB7, TGB1, THBGB1
Keywords3D-structure; Antibiotic; Antimicrobial; Chemotaxis; Cleavage on pair of basic residues; Complete proteome; Cytokine; Direct protein sequencing; Disulfide bond; Growth factor; Mitogen; Reference proteome; Secreted; Signal.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM54995; AAA62836.1; -; mRNA
EMBLAF349466; AAK29642.1; -; Genomic_DNA
EMBLCR456805; CAG33086.1; -; mRNA
EMBLAC097709; AAY41004.1; -; Genomic_DNA
EMBLAK312166; BAG35100.1; -; mRNA
EMBLCH471057; EAX05695.1; -; Genomic_DNA
EMBLBC028217; AAH28217.1; -; mRNA
IPIIPI00022445; -; .
PIRA39546; TGHU; .
RefSeqNP_002695.1; NM_002704.3; .
UniGeneHs.2164; -; .
PDB1F9P; X-ray; 1.93 A; A=44-128
PDB1NAP; X-ray; 1.90 A; A/B/C/D=59-128
PDB1TVX; X-ray; 1.75 A; A/B/C/D=54-128
PDBsum1F9P; -; .
PDBsum1NAP; -; .
PDBsum1TVX; -; .
ProteinModelPortalP02775; -; .
SMRP02775; 44-124; .
DIPDIP-5913N; -; .
IntActP02775; 11; .
MINTMINT-1393871; -; .
STRINGP02775; -; .
SWISS-2DPAGEP02775; -; .
PeptideAtlasP02775; -; .
PRIDEP02775; -; .
EnsemblENST00000296028; ENSP00000296028; ENSG00000163736; .
GeneID5473; -; .
KEGGhsa:5473; -; .
UCSCuc003hhj.1; human; .
CTD5473; -; .
GeneCardsGC04M070663; -; .
H-InvDBHIX0004284; -; .
HGNCHGNC:9240; PPBP; .
HPACAB017624; -; .
HPAHPA008354; -; .
MIM121010; gene; .
neXtProtNX_P02775; -; .
PharmGKBPA33561; -; .
eggNOGprNOG20711; -; .
GeneTreeENSGT00530000062901; -; .
HOGENOMHBG506700; -; .
HOVERGENHBG107789; -; .
InParanoidP02775; -; .
OMAAELRCMC; -; .
OrthoDBEOG4Z8XZ6; -; .
PhylomeDBP02775; -; .
ReactomeREACT_14797; Signaling by GPCR; .
ReactomeREACT_604; Hemostasis; .
NextBio21188; -; .
PMAP-CutDBP02775; -; .
ArrayExpressP02775; -; .
BgeeP02775; -; .
CleanExHS_PPBP; -; .
GenevestigatorP02775; -; .
GermOnlineENSG00000163736; Homo sapiens; .
GOGO:0005615; C:extracellular space; IEA:UniProtKB-KW; .
GOGO:0031093; C:platelet alpha granule lumen; TAS:Reactome; .
GOGO:0008009; F:chemokine activity; IEA:InterPro; .
GOGO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc; .
GOGO:0008083; F:growth factor activity; IEA:UniProtKB-KW; .
GOGO:0006935; P:chemotaxis; IEA:UniProtKB-KW; .
GOGO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW; .
GOGO:0006955; P:immune response; IEA:InterPro; .
GOGO:0030168; P:platelet activation; TAS:Reactome; .
GOGO:0002576; P:platelet degranulation; TAS:Reactome; .
GOGO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW; .
InterProIPR001089; Chemokine_CXC; .
InterProIPR018048; Chemokine_CXC_CS; .
InterProIPR002473; Chemokine_CXCL8/IL8; .
InterProIPR001811; Chemokine_IL8-like_dom; .
PfamPF00048; IL8; 1; .
PRINTSPR00436; INTERLEUKIN8; .
PRINTSPR00437; SMALLCYTKCXC; .
SMARTSM00199; SCY; 1; .
SUPFAMSSF54117; Chemokine_IL8; 1; .
PROSITEPS00471; SMALL_CYTOKINES_CXC; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server