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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P05090 SWISS-2DPAGE:  P05090 P05090 General information about the entry View entry in simple text format Entry name APOD_HUMAN Primary accession number P05090 integrated into SWISS-2DPAGE on  August 1, 1993 (release 0) 2D Annotations were last modified on May 15, 2003 (version 1) General Annotations were last modified on  May 19, 2011 (version 15) Name and origin of the protein Description RecName: Full=Apolipoprotein D; Short=Apo-D; Short=ApoD; Flags: Precursor;. Gene name Name=APOD Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan] Anderson N.L., Anderson N.G. ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'' Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977) [2]   MAPPING ON GEL MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan] Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F. ''''''Inside SWISS-2DPAGE database'';'';'' Electrophoresis 16(1):1131-1151(1995) Comments SUBUNIT: HOMODIMER 2D PAGE maps for identified proteins How to interpret a protein CSF_HUMAN {Cerebrospinal Fluid} Homo sapiens (Human) Tissue: Cerebrospinal fluid   map experimental info   protein estimated location   CSF_HUMAN MAP LOCATIONS: SPOT 2D-000C7N: pI=4.22; Mw=30928 SPOT 2D-000C85: pI=4.21; Mw=30097 SPOT 2D-000C88: pI=4.37; Mw=29801 SPOT 2D-000C8M: pI=4.23; Mw=29144 SPOT 2D-000C8O: pI=4.31; Mw=29072 SPOT 2D-000C8P: pI=4.37; Mw=29000 SPOT 2D-000C8S: pI=4.46; Mw=28714 SPOT 2D-000C8T: pI=4.55; Mw=28714 SPOT 2D-000C94: pI=4.38; Mw=27943 SPOT 2D-000C95: pI=4.46; Mw=27736 SPOT 2D-000C9B: pI=4.55; Mw=27259 SPOT 2D-000C9K: pI=4.67; Mw=26990 SPOT 2D-000C9V: pI=4.79; Mw=26071 SPOT 2D-000CAS: pI=4.80; Mw=24566 MAPPING (identification): MATCHING WITH THE PLASMA MASTER GEL [2]. PLASMA_HUMAN {Plasma} Homo sapiens (Human) Tissue: Plasma   map experimental info   protein estimated location   PLASMA_HUMAN MAP LOCATIONS: SPOT 2D-00058J: pI=4.44; Mw=32256 SPOT 2D-000593: pI=4.50; Mw=31224 SPOT 2D-00059F: pI=4.78; Mw=30225 SPOT 2D-00059I: pI=4.55; Mw=30126 SPOT 2D-00059P: pI=4.51; Mw=29931 SPOT 2D-00059Y: pI=4.61; Mw=29257 SPOT 2D-0005A1: pI=4.55; Mw=29162 SPOT 2D-0005AC: pI=4.68; Mw=28599 SPOT 2D-0005AF: pI=4.61; Mw=28506 SPOT 2D-0005AS: pI=4.77; Mw=28046 SPOT 2D-0005BC: pI=4.77; Mw=27061 SPOT 2D-0005BD: pI=4.88; Mw=27061 NORMAL LEVEL: 80-100 MG/L. PATHOLOGICAL LEVEL: INCREASED DURING TYPE I HYPERLIPAEMIA. MAPPING (identification): IMMUNOBLOTTING [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references UniProtKB/Swiss-Prot P05090; APOD_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name APOD_HUMAN Primary accession number P05090 Secondary accession number(s) B2R579 D3DNW6 Q6IBG6 Sequence was last modified on  August 13, 1987 (version 1) Annotations were last modified on  October 19, 2011 (version 138) Name and origin of the protein Description RecName: Full=Apolipoprotein D; Short=Apo-D; Short=ApoD; Flags: Precursor; Gene name Name=APOD Encoded on Name=APOD Keywords 3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Lipid-binding; Polymorphism; Pyrrolidone carboxylic acid; Reference proteome; Secreted; Signal; Transport. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J02611; AAB59517.1; -; mRNA EMBL M16696; AAA51764.1; -; Genomic_DNA EMBL BT019860; AAV38663.1; -; mRNA EMBL BT019861; AAV38664.1; -; mRNA EMBL CR456838; CAG33119.1; -; mRNA EMBL CR541773; CAG46572.1; -; mRNA EMBL AK312090; BAG35026.1; -; mRNA EMBL CH471052; EAW78023.1; -; Genomic_DNA EMBL CH471052; EAW78024.1; -; Genomic_DNA EMBL BC007402; AAH07402.1; -; mRNA EMBL S80440; AAB35919.1; -; mRNA IPI IPI00006662; -; . PIR A26958; LPHUD; . RefSeq NP_001638.1; NM_001647.3; . UniGene Hs.522555; -; . PDB 2APD; Model; -; A=21-189 PDB 2HZQ; X-ray; 1.80 A; A=23-189 PDB 2HZR; X-ray; 1.80 A; A=23-189 PDBsum 2APD; -; . PDBsum 2HZQ; -; . PDBsum 2HZR; -; . ProteinModelPortal P05090; -; . SMR P05090; 23-188; . IntAct P05090; 2; . MINT MINT-1396020; -; . STRING P05090; -; . SWISS-2DPAGE P05090; -; . PeptideAtlas P05090; -; . PRIDE P05090; -; . Ensembl ENST00000343267; ENSP00000345179; ENSG00000189058; . GeneID 347; -; . KEGG hsa:347; -; . UCSC uc003fur.1; human; . CTD 347; -; . GeneCards GC03M192666; -; . H-InvDB HIX0003987; -; . HGNC HGNC:612; APOD; . MIM 107740; gene; . neXtProt NX_P05090; -; . PharmGKB PA24900; -; . eggNOG prNOG04250; -; . GeneTree ENSGT00510000046981; -; . HOVERGEN HBG018734; -; . InParanoid P05090; -; . OrthoDB EOG4G7C0M; -; . PhylomeDB P05090; -; . NextBio 1431; -; . ArrayExpress P05090; -; . Bgee P05090; -; . CleanEx HS_APOD; -; . Genevestigator P05090; -; . GermOnline ENSG00000189058; Homo sapiens; . GO GO:0005615; C:extracellular space; IDA:BHF-UCL; . GO GO:0008289; F:lipid binding; IEA:UniProtKB-KW; . GO GO:0005319; F:lipid transporter activity; TAS:ProtInc; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0006629; P:lipid metabolic process; TAS:ProtInc; . InterPro IPR002969; ApolipopD; . InterPro IPR012674; Calycin; . InterPro IPR011038; Calycin-like; . InterPro IPR002345; Lipocalin; . InterPro IPR022271; Lipocalin_ApoD; . InterPro IPR022272; Lipocalin_CS; . InterPro IPR000566; Lipocln_cytosolic_FA-bd_dom; . Gene3D G3DSA:2.40.128.20; Calycin; 1; . Pfam PF00061; Lipocalin; 1; . PIRSF PIRSF036893; Lipocalin_ApoD; 1; . PRINTS PR01219; APOLIPOPROTD; . PRINTS PR00179; LIPOCALIN; . SUPFAM SSF50814; Calycin; 1; . PROSITE PS00213; LIPOCALIN; 1; . SWISS-2DPAGE (search AC)