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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: P23246 SWISS-2DPAGE:  P23246 P23246 General information about the entry View entry in simple text format Entry name SFPQ_HUMAN Primary accession number P23246 integrated into SWISS-2DPAGE on  November 9, 2001 (release 15) 2D Annotations were last modified on May 15, 2003 (version 1) General Annotations were last modified on  May 19, 2011 (version 8) Name and origin of the protein Description RecName: Full=Splicing factor, proline-and glutamine-rich; AltName: Full=100 kDa DNA-pairing protein; Short=hPOMp100; AltName: Full=DNA-binding p52/p100 complex, 100 kDa subunit; AltName: Full=Polypyrimidine tract-binding protein-associated-splicing factor; Short=PSF; Short=PTB-associated-splicing factor;. Gene name Name=SFPQ Synonyms=PSF Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) 2D PAGE maps for identified proteins How to interpret a protein NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_1D_HUMAN MAP LOCATIONS: BAND 1D-001V7X: Mw=101482   [identification data] MAPPING (identification): Tandem mass spectrometry [1]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references UniProtKB/Swiss-Prot P23246; SFPQ_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name SFPQ_HUMAN Primary accession number P23246 Secondary accession number(s) P30808 Q5SZ71 Sequence was last modified on  October 1, 1996 (version 2) Annotations were last modified on  October 19, 2011 (version 135) Name and origin of the protein Description RecName: Full=Splicing factor, proline-and glutamine-rich; AltName: Full=100 kDa DNA-pairing protein; Short=hPOMp100; AltName: Full=DNA-binding p52/p100 complex, 100 kDa subunit; AltName: Full=Polypyrimidine tract-binding protein-associated-splicing factor; Short=PSF; Short=PTB-associated-splicing factor; Gene name Name=SFPQ Synonyms=PSF Encoded on Name=SFPQ; Synonyms=PSF Keywords Acetylation; Activator; Alternative splicing; Chromosomal rearrangement; Complete proteome; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; DNA-binding; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding; Transcription; Transcription regulation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X70944; CAA50283.1; -; mRNA EMBL AL590434; CAI12467.1; -; Genomic_DNA EMBL CH471059; EAX07426.1; -; Genomic_DNA EMBL X16850; CAA34747.1; -; mRNA IPI IPI00010740; -; . IPI IPI00216613; -; . PIR A46302; A46302; . PIR S29770; S29770; . RefSeq NP_005057.1; NM_005066.2; . UniGene Hs.355934; -; . ProteinModelPortal P23246; -; . SMR P23246; 290-521; . IntAct P23246; 30; . MINT MINT-1141893; -; . STRING P23246; -; . PhosphoSite P23246; -; . SWISS-2DPAGE P23246; -; . PeptideAtlas P23246; -; . PRIDE P23246; -; . Ensembl ENST00000357214; ENSP00000349748; ENSG00000116560; . GeneID 6421; -; . KEGG hsa:6421; -; . UCSC uc001bys.1; human; . CTD 6421; -; . GeneCards GC01M033767; -; . H-InvDB HIX0000409; -; . HGNC HGNC:10774; SFPQ; . HPA CAB009886; -; . MIM 605199; gene; . neXtProt NX_P23246; -; . PharmGKB PA35690; -; . eggNOG prNOG14923; -; . HOGENOM HBG126336; -; . HOVERGEN HBG009801; -; . InParanoid P23246; -; . OMA APGGHPK; -; . OrthoDB EOG4RNB8S; -; . PhylomeDB P23246; -; . NextBio 24935; -; . ArrayExpress P23246; -; . Bgee P23246; -; . CleanEx HS_SFPQ; -; . Genevestigator P23246; -; . GermOnline ENSG00000116560; Homo sapiens; . GO GO:0016363; C:nuclear matrix; IDA:BHF-UCL; . GO GO:0042382; C:paraspeckles; IDA:BHF-UCL; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IEA:UniProtKB-KW; . GO GO:0000380; P:alternative nuclear mRNA splicing; via spliceosome; IMP:BHF-UCL GO GO:0006310; P:DNA recombination; IEA:UniProtKB-KW; . GO GO:0006281; P:DNA repair; IEA:UniProtKB-KW; . GO GO:0006355; P:regulation of transcription; DNA-dependent; IEA:UniProtKB-KW GO GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW InterPro IPR012975; NOPS; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Gene3D G3DSA:3.30.70.330; a_b_plait_nuc_bd; 2; . Pfam PF08075; NOPS; 1; . Pfam PF00076; RRM_1; 2; . SMART SM00360; RRM; 2; . PROSITE PS50102; RRM; 2; . SWISS-2DPAGE (search AC)