resource logo

SWISS-2DPAGE

Attention: World-2DPAGE is no longer maintained.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P63261




SWISS-2DPAGE:  P63261


P63261


General information about the entry
View entry in simple text format
Entry nameACTG_HUMAN
Primary accession numberP63261
Secondary accession number(s) P02571
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;.
Gene nameName=ACTG1
Synonyms=ACTB, ACTG
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
Comments
  • SUBUNIT: POLYMERIZATION OF GLOBULAR ACTIN (G-ACTIN) LEADS TO A STRUCTURAL FILAMENT (F-ACTIN) IN THE FORM OF A TWO-STRANDED HELIX. EACH ACTIN CAN BIND TO 4 OTHERS
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=45031  [identification data]
Mw=43891  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
DOSAC-COBS 2D-PAGEP63261; P63261.
DOSAC-COBS-2DPAGEP63261; ACTG_HUMAN.
OGP-WWWP02571.
PMMA-2DPAGEP02571.
REPRODUCTION-2DPAGEP63261; P63261.
UniProtKB/Swiss-ProtP63261; ACTG_HUMAN.
World-2DPAGE RepositoryP63261; ACTG_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameACTG_HUMAN
Primary accession numberP63261
Secondary accession number(s) A8K7C2 P02571 P14104 P99022 Q5U032 Q96E67
Sequence was last modified on July 21, 1986 (version 1)
Annotations were last modified on October 19, 2011 (version 94)
Name and origin of the protein
DescriptionRecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;
Gene nameName=ACTG1
Synonyms=ACTB, ACTG
Encoded onName=ACTG1; Synonyms=ACTB, ACTG
KeywordsAcetylation; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Disease mutation; Methylation; Non-syndromic deafness; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX04098; CAA27723.1; -; mRNA
EMBLM19283; AAA51579.1; -; Genomic_DNA
EMBLAK291937; BAF84626.1; -; mRNA
EMBLBT019856; AAV38659.1; -; mRNA
EMBLBC000292; AAH00292.1; -; mRNA
EMBLBC001920; AAH01920.1; -; mRNA
EMBLBC007442; AAH07442.1; -; mRNA
EMBLBC009848; AAH09848.1; -; mRNA
EMBLBC010999; AAH10999.1; -; mRNA
EMBLBC012050; AAH12050.1; -; mRNA
EMBLBC015005; AAH15005.1; -; mRNA
EMBLBC015695; AAH15695.1; -; mRNA
EMBLBC015779; AAH15779.1; -; mRNA
EMBLBC018774; AAH18774.1; -; mRNA
EMBLBC053572; AAH53572.1; -; mRNA
EMBLM16247; AAA51580.1; -; mRNA
IPIIPI00021440; -; .
PIRA28098; ATHUG; .
PIRJC5818; JC5818; .
RefSeqNP_001186883.1; NM_001199954.1; .
RefSeqNP_001605.1; NM_001614.3; .
UniGeneHs.514581; -; .
ProteinModelPortalP63261; -; .
SMRP63261; 2-375; .
IntActP63261; 32; .
MINTMINT-4998686; -; .
STRINGP63261; -; .
PhosphoSiteP63261; -; .
SWISS-2DPAGEP63261; -; .
DOSAC-COBS-2DPAGEP60709_OR_P63261; -; .
DOSAC-COBS-2DPAGEP63261; -; .
OGPP63261; -; .
PMMA-2DPAGEP63261; -; .
REPRODUCTION-2DPAGEP63261; -; .
PRIDEP63261; -; .
EnsemblENST00000331925; ENSP00000331514; ENSG00000184009; .
GeneID71; -; .
KEGGhsa:71; -; .
UCSCuc002kaj.1; human; .
CTD71; -; .
GeneCardsGC17M074925; -; .
H-InvDBHIX0020804; -; .
HGNCHGNC:144; ACTG1; .
HPACAB013531; -; .
MIM102560; gene; .
MIM604717; phenotype; .
neXtProtNX_P63261; -; .
Orphanet90635; Autosomal dominant nonsyndromic sensorineural deafness type DFNA; .
PharmGKBPA24468; -; .
HOVERGENHBG003771; -; .
InParanoidP63261; -; .
OMAIAMEEEI; -; .
OrthoDBEOG41JZC9; -; .
PhylomeDBP63261; -; .
ReactomeREACT_11123; Membrane Trafficking; .
ReactomeREACT_18266; Axon guidance; .
ReactomeREACT_20676; Cell junction organization; .
ReactomeREACT_604; Hemostasis; .
NextBio279; -; .
PMAP-CutDBP63261; -; .
ArrayExpressP63261; -; .
BgeeP63261; -; .
CleanExHS_ACTB; -; .
CleanExHS_ACTG1; -; .
GenevestigatorP63261; -; .
GermOnlineENSG00000184009; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0005200; F:structural constituent of cytoskeleton; IC:UniProtKB; .
GOGO:0034332; P:adherens junction organization; TAS:Reactome; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0007596; P:blood coagulation; TAS:Reactome; .
GOGO:0034329; P:cell junction assembly; TAS:Reactome; .
GOGO:0006928; P:cellular component movement; TAS:UniProtKB; .
InterProIPR004000; Actin-like; .
InterProIPR020902; Actin/actin-like_CS; .
InterProIPR004001; Actin_CS; .
PANTHERPTHR11937; Actin_like; 1; .
PfamPF00022; Actin; 1; .
PRINTSPR00190; ACTIN; .
SMARTSM00268; ACTIN; 1; .
PROSITEPS00406; ACTINS_1; 1; .
PROSITEPS00432; ACTINS_2; 1; .
PROSITEPS01132; ACTINS_ACT_LIKE; 1; .



SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server