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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: APT_HUMAN



General information about the entry
View entry in simple text format
Entry nameAPT_HUMAN
Primary accession numberP07741
integrated into SWISS-2DPAGE on March 31, 2004 (release 17)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 5)
Name and origin of the protein
DescriptionRecName: Full=Adenine phosphoribosyltransferase; Short=APRT; EC=;.
Gene nameName=APRT
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D.
''''''New insights into HIV lymphocyte infection'';'';''
(IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
  • SUBUNIT: Homodimer
2D PAGE maps for identified proteins
How to interpret a protein

Homo sapiens (Human)
Tissue: Lymphocyte
  map experimental info
  protein estimated location

pI=5.39; Mw=20864  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP07741; APT_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameAPT_HUMAN
Primary accession numberP07741
Secondary accession number(s) Q3KP55 Q68DF9
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on October 19, 2011 (version 135)
Name and origin of the protein
DescriptionRecName: Full=Adenine phosphoribosyltransferase; Short=APRT; EC=;
Gene nameName=APRT
Encoded onName=APRT
Keywords3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Glycosyltransferase; Phosphoprotein; Polymorphism; Purine salvage; Reference proteome; Transferase.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLY00486; CAA68543.1; -; Genomic_DNA
EMBLM16446; AAA51769.1; -; Genomic_DNA
EMBLCR749423; CAH18261.1; -; mRNA
EMBLAY306126; AAP45051.1; -; Genomic_DNA
EMBLBC107151; AAI07152.1; -; mRNA
IPIIPI00218693; -; .
PIRS06232; RTHUA; .
RefSeqNP_000476.1; NM_000485.2; .
UniGeneHs.28914; -; .
PDB1OPU; Model; -; A=1-180
PDB1ORE; X-ray; 2.10 A; A=1-180
PDB1ZN7; X-ray; 1.83 A; A/B=1-180
PDB1ZN8; X-ray; 1.76 A; A/B=1-180
PDB1ZN9; X-ray; 2.05 A; A/B=1-180
PDBsum1OPU; -; .
PDBsum1ORE; -; .
PDBsum1ZN7; -; .
PDBsum1ZN8; -; .
PDBsum1ZN9; -; .
ProteinModelPortalP07741; -; .
SMRP07741; 2-180; .
IntActP07741; 1; .
STRINGP07741; -; .
PhosphoSiteP07741; -; .
SWISS-2DPAGEP07741; -; .
PRIDEP07741; -; .
EnsemblENST00000378364; ENSP00000367615; ENSG00000198931; .
GeneID353; -; .
KEGGhsa:353; -; .
NMPDRfig|9606.3.peg.12727; -; .
UCSCuc002flv.1; human; .
CTD353; -; .
GeneCardsGC16M074573; -; .
H-InvDBHIX0038644; -; .
HPAHPA026681; -; .
MIM102600; gene+phenotype; .
neXtProtNX_P07741; -; .
Orphanet976; 2; 8 dihydroxyadenine urolithiasis; .
PharmGKBPA24914; -; .
eggNOGprNOG19348; -; .
HOGENOMHBG703830; -; .
HOVERGENHBG003144; -; .
InParanoidP07741; -; .
OrthoDBEOG48KRCC; -; .
PhylomeDBP07741; -; .
BRENDA2.4.2.7; 2681; .
ReactomeREACT_1698; Metabolism of nucleotides; .
DrugBankDB00173; Adenine; .
DrugBankDB00131; Adenosine monophosphate; .
NextBio1453; -; .
ArrayExpressP07741; -; .
BgeeP07741; -; .
CleanExHS_APRT; -; .
GenevestigatorP07741; -; .
GermOnlineENSG00000198931; Homo sapiens; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005634; C:nucleus; IDA:HPA; .
GOGO:0003999; F:adenine phosphoribosyltransferase activity; TAS:Reactome; .
GOGO:0016208; F:AMP binding; IDA:MGI; .
GOGO:0006168; P:adenine salvage; IEA:InterPro; .
GOGO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW; .
InterProIPR005764; Ade_phspho_trans; .
InterProIPR000836; PRibTrfase; .
PfamPF00156; Pribosyltran; 1; .
TIGRFAMsTIGR01090; Apt; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server