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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: DDX5_HUMAN



General information about the entry
View entry in simple text format
Entry nameDDX5_HUMAN
Primary accession numberP17844
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 7)
Name and origin of the protein
DescriptionRecName: Full=Probable ATP-dependent RNA helicase DDX5; EC=; AltName: Full=DEAD box protein 5; AltName: Full=RNA helicase p68;.
Gene nameName=DDX5
Synonyms=G17P1, HELR, HLR1
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
  map experimental info
  protein estimated location

Mw=65137  [identification data]

MAPPING (identification):
Peptide mass fingerprinting and tandem mass SPECTROMETRY [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP17844; DDX5_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDDX5_HUMAN
Primary accession numberP17844
Secondary accession number(s) B5BU21 D3DU32 O75681 Q53Y61
Sequence was last modified on August 1, 1990 (version 1)
Annotations were last modified on October 19, 2011 (version 136)
Name and origin of the protein
DescriptionRecName: Full=Probable ATP-dependent RNA helicase DDX5; EC=; AltName: Full=DEAD box protein 5; AltName: Full=RNA helicase p68;
Gene nameName=DDX5
Synonyms=G17P1, HELR, HLR1
Encoded onName=DDX5; Synonyms=G17P1, HELR, HLR1
Keywords3D-structure; Acetylation; ATP-binding; Complete proteome; Helicase; Hydrolase; Methylation; mRNA processing; mRNA splicing; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; RNA-binding; Spliceosome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX52104; CAA36324.1; -; mRNA
EMBLAF015812; AAB84094.1; -; Genomic_DNA
EMBLBT006943; AAP35589.1; -; mRNA
EMBLAB451257; BAG70071.1; -; mRNA
EMBLCH471109; EAW94202.1; -; Genomic_DNA
EMBLCH471109; EAW94203.1; -; Genomic_DNA
EMBLBC016027; AAH16027.1; -; mRNA
EMBLX15729; CAA33751.1; -; mRNA
EMBLAJ010931; CAA09408.1; -; Genomic_DNA
IPIIPI00017617; -; .
PIRJC1087; JC1087; .
RefSeqNP_004387.1; NM_004396.3; .
UniGeneHs.279806; -; .
PDB3FE2; X-ray; 2.60 A; A/B=68-307
PDBsum3FE2; -; .
ProteinModelPortalP17844; -; .
SMRP17844; 71-478; .
DIPDIP-29844N; -; .
IntActP17844; 37; .
MINTMINT-5000516; -; .
STRINGP17844; -; .
PhosphoSiteP17844; -; .
SWISS-2DPAGEP17844; -; .
Aarhus/Ghent-2DPAGE1605; NEPHGE; .
PeptideAtlasP17844; -; .
PRIDEP17844; -; .
EnsemblENST00000225792; ENSP00000225792; ENSG00000108654; .
GeneID1655; -; .
KEGGhsa:1655; -; .
UCSCuc002jek.1; human; .
CTD1655; -; .
GeneCardsGC17M057943; -; .
HGNCHGNC:2746; DDX5; .
HPACAB005868; -; .
HPAHPA020043; -; .
MIM180630; gene; .
neXtProtNX_P17844; -; .
PharmGKBPA27228; -; .
eggNOGprNOG04242; -; .
HOGENOMHBG737336; -; .
HOVERGENHBG015893; -; .
InParanoidP17844; -; .
OrthoDBEOG4BVRTM; -; .
PhylomeDBP17844; -; .
NextBio6816; -; .
ArrayExpressP17844; -; .
BgeeP17844; -; .
CleanExHS_DDX5; -; .
GenevestigatorP17844; -; .
GermOnlineENSG00000108654; Homo sapiens; .
GOGO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; .
GOGO:0005730; C:nucleolus; IEA:UniProtKB-SubCell; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0008026; F:ATP-dependent helicase activity; IEA:InterPro; .
GOGO:0003729; F:mRNA binding; IDA:UniProtKB; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0003724; F:RNA helicase activity; IMP:UniProtKB; .
GOGO:0003712; F:transcription cofactor activity; IEA:InterPro; .
GOGO:0016049; P:cell growth; NAS:UniProtKB; .
GOGO:0000398; P:nuclear mRNA splicing; via spliceosome; IC:UniProtKB
GOGO:0000381; P:regulation of alternative nuclear mRNA splicing; via spliceosome; IDA:UniProtKB
InterProIPR014001; DEAD-like_helicase; .
InterProIPR011545; DNA/RNA_helicase_DEAD/DEAH_N; .
InterProIPR001650; Helicase_C; .
InterProIPR012587; P68HR; .
InterProIPR000629; RNA-helicase_DEAD-box_CS; .
InterProIPR014014; RNA_helicase_DEAD_Q_motif; .
PfamPF00270; DEAD; 1; .
PfamPF00271; Helicase_C; 1; .
PfamPF08061; P68HR; 2; .
SMARTSM00487; DEXDc; 1; .
SMARTSM00490; HELICc; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server