resource logo


Attention: World-2DPAGE is no longer maintained.
It will be discontinued on 31-May-2024.

Swiss-2DPAGE data (text records and image files) will continue to be available from

Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected

Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: DEGP_ECOLI



General information about the entry
View entry in simple text format
Entry nameDEGP_ECOLI
Primary accession numberP0C0V0
Secondary accession number(s) P09376
integrated into SWISS-2DPAGE on December 1, 2000 (release 13)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 11)
Name and origin of the protein
DescriptionRecName: Full=Protease do; EC=3.4.21.-; Flags: Precursor;.
Gene nameName=degP
Synonyms=htrA, ptd
OrderedLocusNames=b0161, JW0157
Annotated speciesEscherichia coli [TaxID: 562]
TaxonomyBacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
PubMed=11680886; [NCBI, Expasy, EBI, Israel, Japan]
Tonella L., Hoogland C., Binz P.-A., Appel R.D., Hochstrasser D.F., Sanchez J.-C.
''''''New perspectives in the Escherichia coli proteome investigation'';'';''
Proteomics 1(1):409-423(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ECOLI6-11 {Escherichia coli(6-11)}
Escherichia coli
  map experimental info
  protein estimated location

pI=8.01; Mw=66440  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP0C0V0; DEGP_ECOLI.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameDEGP_ECOLI
Primary accession numberP0C0V0
Secondary accession number(s) P09376 P15724
Sequence was last modified on December 20, 2005 (version 1)
Annotations were last modified on October 19, 2011 (version 64)
Name and origin of the protein
DescriptionRecName: Full=Protease do; EC=3.4.21.-; Flags: Precursor;
Gene nameName=degP
Synonyms=htrA, ptd
OrderedLocusNames=b0161, JW0157
Encoded onName=degP; Synonyms=htrA, ptd; OrderedLocusNames=b0161, JW0157
Keywords3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Hydrolase; Periplasm; Protease; Reference proteome; Repeat; Serine protease; Signal; Stress response.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLM36536; AAA23994.1; -; Genomic_DNA
EMBLX12457; CAA30997.1; -; Genomic_DNA
EMBLU70214; AAB08591.1; -; Genomic_DNA
EMBLU00096; AAC73272.1; -; Genomic_DNA
EMBLAP009048; BAB96738.1; -; Genomic_DNA
EMBLM29955; AAA23717.1; -; Genomic_DNA
EMBLM31772; AAA23680.1; -; Genomic_DNA
PIRS45229; S45229; .
RefSeqNP_414703.1; NC_000913.2; .
PDB1KY9; X-ray; 2.80 A; A/B=27-474
PDB2ZLE; EM; 28.00 A; A/B/C/E/F/G/H/I/J/K/L/M=27-474
PDB3CS0; X-ray; 3.00 A; A=27-474
PDB3MH4; X-ray; 3.10 A; A/B=27-474
PDB3MH5; X-ray; 3.00 A; A/B=27-474
PDB3MH6; X-ray; 3.60 A; A=27-474
PDB3MH7; X-ray; 2.96 A; A=27-474
PDB3OTP; X-ray; 3.76 A; A/B/C/D/E/F=27-474
PDB3OU0; X-ray; 3.00 A; A=27-474
PDBsum1KY9; -; .
PDBsum2ZLE; -; .
PDBsum3CS0; -; .
PDBsum3MH4; -; .
PDBsum3MH5; -; .
PDBsum3MH6; -; .
PDBsum3MH7; -; .
PDBsum3OTP; -; .
PDBsum3OU0; -; .
ProteinModelPortalP0C0V0; -; .
SMRP0C0V0; 37-472; .
DIPDIP-46256N; -; .
IntActP0C0V0; 9; .
MINTMINT-1302319; -; .
MEROPSS01.273; -; .
PRIDEP0C0V0; -; .
EnsemblBacteriaEBESCT00000002861; EBESCP00000002861; EBESCG00000002334; .
EnsemblBacteriaEBESCT00000015521; EBESCP00000014812; EBESCG00000014581; .
GeneID947139; -; .
GenomeReviewsAP009048_GR; JW0157; .
GenomeReviewsU00096_GR; b0161; .
KEGGecj:JW0157; -; .
KEGGeco:b0161; -; .
EchoBASEEB0458; -; .
EcoGeneEG10463; degP; .
eggNOGCOG0265; -; .
GeneTreeEBGT00050000010522; -; .
HOGENOMHBG585708; -; .
ProtClustDBPRK10942; -; .
BioCycEcoCyc:EG10463-MONOMER; -; .
BioCycMetaCyc:EG10463-MONOMER; -; .
GenevestigatorP0C0V0; -; .
GOGO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoliWiki; .
GOGO:0005515; F:protein binding; IPI:IntAct; .
GOGO:0004252; F:serine-type endopeptidase activity; IDA:EcoliWiki; .
GOGO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:EcoliWiki; .
GOGO:0006457; P:protein folding; IMP:EcoliWiki; .
GOGO:0006979; P:response to oxidative stress; IEP:EcoliWiki; .
GOGO:0009266; P:response to temperature stimulus; IEP:EcoliWiki; .
InterProIPR001478; PDZ/DHR/GLGF; .
InterProIPR009003; Pept_cys/ser_Trypsin-like; .
InterProIPR011782; Pept_S1C_Do; .
InterProIPR001254; Peptidase_S1_S6; .
InterProIPR001940; Peptidase_S1C; .
PfamPF00595; PDZ; 2; .
PfamPF00089; Trypsin; 1; .
SMARTSM00228; PDZ; 2; .
SUPFAMSSF50156; PDZ; 2; .
SUPFAMSSF50494; Pept_Ser_Cys; 1; .
TIGRFAMsTIGR02037; DegP_htrA_DO; 1; .
PROSITEPS50106; PDZ; 2; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server