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Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: EZRI_HUMAN



General information about the entry
View entry in simple text format
Entry nameEZRI_HUMAN
Primary accession numberP15311
integrated into SWISS-2DPAGE on January 15, 1999 (release 9)
2D Annotations were last modified onOctober 1, 2001 (version 1)
General Annotations were last modified on May 19, 2011 (version 9)
Name and origin of the protein
DescriptionRecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81;.
Gene nameName=EZR
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F.
Submitted (JAN-1999) to SWISS-2DPAGE
2D PAGE maps for identified proteins
How to interpret a protein

DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)}
Homo sapiens (Human)
Tissue: Colon adenocarcinoma
  map experimental info
  protein estimated location

pI=6.03; Mw=86045  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
DOSAC-COBS 2D-PAGEP15311; P15311.
UniProtKB/Swiss-ProtP15311; EZRI_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameEZRI_HUMAN
Primary accession numberP15311
Secondary accession number(s) E1P5A8 P23714 Q4VX75 Q96CU8 Q9NSJ4
Sequence was last modified on February 6, 2007 (version 4)
Annotations were last modified on October 19, 2011 (version 136)
Name and origin of the protein
DescriptionRecName: Full=Ezrin; AltName: Full=Cytovillin; AltName: Full=Villin-2; AltName: Full=p81;
Gene nameName=EZR
Encoded onName=EZR; Synonyms=VIL2
Keywords3D-structure; Acetylation; Cell membrane; Cell projection; Cell shape; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Membrane; Phosphoprotein; Polymorphism; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLX51521; CAA35893.1; -; mRNA
EMBLJ05021; AAA61278.1; ALT_INIT; mRNA
EMBLAL162086; CAB82418.1; ALT_INIT; mRNA
EMBLAL589931; CAI95307.1; -; Genomic_DNA
EMBLCH471051; EAW47647.1; -; Genomic_DNA
EMBLBC013903; AAH13903.1; -; mRNA
IPIIPI00843975; -; .
PIRA34400; A34400; .
RefSeqNP_001104547.1; NM_001111077.1; .
RefSeqNP_003370.2; NM_003379.4; .
UniGeneHs.487027; -; .
PDB1NI2; X-ray; 2.30 A; A/B=2-297
PDBsum1NI2; -; .
ProteinModelPortalP15311; -; .
SMRP15311; 1-586; .
IntActP15311; 8; .
MINTMINT-195721; -; .
STRINGP15311; -; .
PhosphoSiteP15311; -; .
SWISS-2DPAGEP15311; -; .
PRIDEP15311; -; .
EnsemblENST00000337147; ENSP00000338934; ENSG00000092820; .
EnsemblENST00000367075; ENSP00000356042; ENSG00000092820; .
GeneID7430; -; .
KEGGhsa:7430; -; .
UCSCuc003qrt.2; human; .
CTD7430; -; .
GeneCardsGC06M156657; -; .
H-InvDBHIX0006334; -; .
HGNCHGNC:12691; EZR; .
HPACAB004035; -; .
HPAHPA021616; -; .
MIM123900; gene; .
neXtProtNX_P15311; -; .
PharmGKBPA162385512; -; .
eggNOGprNOG04610; -; .
HOGENOMHBG446392; -; .
HOVERGENHBG002185; -; .
OrthoDBEOG4C5CJJ; -; .
PhylomeDBP15311; -; .
Pathway_Interaction_DBsyndecan_2_pathway; Syndecan-2-mediated signaling events; .
ReactomeREACT_18266; Axon guidance; .
NextBio29100; -; .
ArrayExpressP15311; -; .
BgeeP15311; -; .
CleanExHS_EZR; -; .
GenevestigatorP15311; -; .
GermOnlineENSG00000092820; Homo sapiens; .
GOGO:0005884; C:actin filament; IDA:HGNC; .
GOGO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell; .
GOGO:0016323; C:basolateral plasma membrane; ISS:UniProtKB; .
GOGO:0030863; C:cortical cytoskeleton; TAS:HGNC; .
GOGO:0005829; C:cytosol; IDA:UniProtKB; .
GOGO:0019898; C:extrinsic to membrane; IDA:UniProtKB; .
GOGO:0030175; C:filopodium; IDA:BHF-UCL; .
GOGO:0031528; C:microvillus membrane; IEA:UniProtKB-SubCell; .
GOGO:0005730; C:nucleolus; IDA:HPA; .
GOGO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; .
GOGO:0051015; F:actin filament binding; IDA:UniProtKB; .
GOGO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL; .
GOGO:0051017; P:actin filament bundle assembly; IDA:UniProtKB; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB; .
GOGO:0007159; P:leukocyte cell-cell adhesion; IEP:BHF-UCL; .
GOGO:0022614; P:membrane to membrane docking; IEP:BHF-UCL; .
GOGO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW; .
InterProIPR019749; Band_41_domain; .
InterProIPR019750; Band_41_fam; .
InterProIPR011174; ERM; .
InterProIPR011259; ERM_C; .
InterProIPR000798; Ez/rad/moesin; .
InterProIPR014352; FERM/acyl-CoA-bd_prot_3-hlx; .
InterProIPR019748; FERM_central; .
InterProIPR019747; FERM_CS; .
InterProIPR000299; FERM_domain; .
InterProIPR018979; FERM_N; .
InterProIPR018980; FERM_PH-like_C; .
InterProIPR008954; Moesin; .
InterProIPR011993; PH_type; .
Gene3DG3DSA:; ACBP; 1; .
Gene3DG3DSA:; PH_type; 1; .
PfamPF00769; ERM; 1; .
PfamPF09380; FERM_C; 1; .
PfamPF00373; FERM_M; 1; .
PfamPF09379; FERM_N; 1; .
PIRSFPIRSF002305; ERM; 1; .
PRINTSPR00935; BAND41; .
SMARTSM00295; B41; 1; .
SUPFAMSSF47031; FERM_3-hlx; 1; .
SUPFAMSSF48678; Moesin; 1; .
PROSITEPS00660; FERM_1; 1; .
PROSITEPS00661; FERM_2; 1; .
PROSITEPS50057; FERM_3; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server