resource logo


Attention: World-2DPAGE is no longer maintained.
It will be discontinued on 31-May-2024.

Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected

Sample Preparation and Post-separation Analysis

Searching in 'SWISS-2DPAGE' for entry matching: GLRX4_ECOLI



General information about the entry
View entry in simple text format
Entry nameGLRX4_ECOLI
Primary accession numberP0AC69
Secondary accession number(s) P37010
integrated into SWISS-2DPAGE on October 1, 1998 (release 8)
2D Annotations were last modified onDecember 30, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 14)
Name and origin of the protein
DescriptionRecName: Full=Glutaredoxin-4; Short=Grx4; AltName: Full=Monothiol glutaredoxin;.
Gene nameName=grxD
OrderedLocusNames=b1654, JW1646
Annotated speciesEscherichia coli [TaxID: 562]
TaxonomyBacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
PubMed=11680886; [NCBI, Expasy, EBI, Israel, Japan]
Tonella L., Hoogland C., Binz P.-A., Appel R.D., Hochstrasser D.F., Sanchez J.-C.
''''''New perspectives in the Escherichia coli proteome investigation'';'';''
Proteomics 1(1):409-423(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ECOLI4.5-5.5 {Escherichia coli(4.5-5.5)}
Escherichia coli
  map experimental info
  protein estimated location

pI=4.96; Mw=10012  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [1].

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See or send email from
UniProtKB/Swiss-ProtP0AC69; GLRX4_ECOLI.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameGLRX4_ECOLI
Primary accession numberP0AC69
Secondary accession number(s) P37010 P77424
Sequence was last modified on November 8, 2005 (version 1)
Annotations were last modified on October 19, 2011 (version 50)
Name and origin of the protein
DescriptionRecName: Full=Glutaredoxin-4; Short=Grx4; AltName: Full=Monothiol glutaredoxin;
Gene nameName=grxD
OrderedLocusNames=b1654, JW1646
Encoded onName=grxD; Synonyms=ydhD; OrderedLocusNames=b1654, JW1646
Keywords2Fe-2S; 3D-structure; Complete proteome; Cytoplasm; Iron; Iron-sulfur; Metal-binding; Redox-active center; Reference proteome.
Copyrighted by the UniProt Consortium, see Distributed under the Creative Commons Attribution-NoDerivs License
EMBLU00096; AAC74726.1; -; Genomic_DNA
EMBLAP009048; BAA15420.1; -; Genomic_DNA
EMBLL01622; AAC37010.1; -; Genomic_DNA
PIRH64922; H64922; .
RefSeqNP_416171.1; NC_000913.2; .
PDB1YKA; NMR; -; A=1-115
PDB2WCI; X-ray; 1.90 A; A/B=1-115
PDBsum1YKA; -; .
PDBsum2WCI; -; .
ProteinModelPortalP0AC69; -; .
SMRP0AC69; 1-115; .
DIPDIP-11729N; -; .
IntActP0AC69; 18; .
MINTMINT-1258030; -; .
PRIDEP0AC69; -; .
EnsemblBacteriaEBESCT00000004891; EBESCP00000004891; EBESCG00000003992; .
EnsemblBacteriaEBESCT00000016322; EBESCP00000015613; EBESCG00000015382; .
GeneID946169; -; .
GenomeReviewsAP009048_GR; JW1646; .
GenomeReviewsU00096_GR; b1654; .
KEGGecj:JW1646; -; .
KEGGeco:b1654; -; .
EchoBASEEB2098; -; .
EcoGeneEG12181; grxD; .
eggNOGCOG0278; -; .
GeneTreeEBGT00050000010422; -; .
HOGENOMHBG728471; -; .
ProtClustDBPRK10824; -; .
BioCycEcoCyc:EG12181-MONOMER; -; .
GenevestigatorP0AC69; -; .
GOGO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell; .
GOGO:0051537; F:2 iron; 2 sulfur cluster binding; IEA:UniProtKB-KW
GOGO:0009055; F:electron carrier activity; IEA:InterPro; .
GOGO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GOGO:0005515; F:protein binding; IPI:IntAct; .
GOGO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; .
GOGO:0045454; P:cell redox homeostasis; IEA:InterPro; .
InterProIPR002109; Glutaredoxin; .
InterProIPR014434; Monothiol_GRX; .
InterProIPR004480; Monothiol_GRX-rel; .
InterProIPR012336; Thioredoxin-like_fold; .
Gene3DG3DSA:; Thioredoxin_fold; 1; .
PANTHERPTHR10293; Glutredox-rel; 1; .
PfamPF00462; Glutaredoxin; 1; .
PIRSFPIRSF005894; Monothiol_GRX; 1; .
SUPFAMSSF52833; Thiordxn-like_fd; 1; .
TIGRFAMsTIGR00365; TIGR00365; 1; .


SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server