General information about the entry |
View entry in simple text format |
Entry name | HBB_HUMAN |
Primary accession number | P68871 |
Secondary accession number(s) | P02023 |
integrated into SWISS-2DPAGE on | August 1, 1993 (release 0) |
2D Annotations were last modified on | March 31, 2004 (version 4) |
General Annotations were last modified on | May 19, 2011 (version 16) |
Name and origin of the protein |
Description | RecName: Full=Hemoglobin subunit beta; AltName: Full=Beta-globin; AltName: Full=Hemoglobin beta chain; Contains: RecName: Full=LVV-hemorphin-7;. |
Gene name | Name=HBB
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Annotated species | Homo sapiens (Human) [TaxID: 9606] |
Taxonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
References |
[1] |
MAPPING ON GEL MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J. ''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';'' Electrophoresis 13(1):992-1001(1992)
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[2] |
MAPPING ON GEL MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F. ''''''Inside SWISS-2DPAGE database'';'';'' Electrophoresis 16(1):1131-1151(1995)
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[3] |
MAPPING ON GEL MEDLINE=79188222; PubMed=109131; [NCBI, Expasy, EBI, Israel, Japan]
Edwards J., Anderson N.G., Nance S.L., Anderson N.L. ''''''Red cell proteins. I. Two-dimensional mapping of human erythrocyte lysate proteins'';'';'' Blood 53(1):1121-1132(1979)
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[4] |
MAPPING ON GEL MEDLINE=93120196; PubMed=1477117; [NCBI, Expasy, EBI, Israel, Japan]
Golaz O., Walzer C., Hochstrasser D.F., Bjellqvist B., Turler H., Balant L.P. ''''''Red blood cell protein map: a comparison between carrier-ampholyte pH gradient and immobilized pH gradient, and identification of four red blood cell enzymes'';'';'' Appl. Theor. Electrophor. 3(1):77-82(1992)
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[5] |
MAPPING ON GEL MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan]
Anderson N.L., Anderson N.G. ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'' Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977)
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[6] |
MAPPING ON GEL MEDLINE=96007935; PubMed=7498158; [NCBI, Expasy, EBI, Israel, Japan]
Gravel P., Sanchez J.-C., Walzer C., Golaz O., Hochstrasser D.F., Balant L.P., Hughes G.J., Garcia-Sevilla J., Guimon J. ''''''Human blood platelet protein map established by two-dimensional polyacrylamide gel electrophoresis'';'';'' Electrophoresis 16(1):1152-1159(1995)
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[7] |
MAPPING ON GEL MEDLINE=98163346; PubMed=9504818; [NCBI, Expasy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F. ''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';'' Electrophoresis 18(1):2842-2848(1997)
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[8] |
MAPPING ON GEL Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F. Submitted (JAN-1999) to SWISS-2DPAGE
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[9] |
MAPPING ON GEL Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider P., Tissot J.-D. ''''''New insights into HIV lymphocyte infection'';'';'' (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.)Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004)
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Comments |
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2D PAGE maps for identified proteins
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How to interpret a protein
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CEC_HUMAN {Colorectal epithelia cells} Homo sapiens (Human)
Tissue: Colon epithelium
map experimental info protein estimated location
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CEC_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL AND MICROSEQUENCING [7].
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DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)} Homo sapiens (Human)
Tissue: Colon adenocarcinoma
map experimental info protein estimated location
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DLD1_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE HEPG2 MASTER GEL [8].
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HEPG2_HUMAN {HepG2} Homo sapiens (Human)
Tissue: Hepatoblastoma
map experimental info protein estimated location
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HEPG2_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
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HEPG2SP_HUMAN {HepG2 Secreted Proteins} Homo sapiens (Human)
Tissue: Hepatoblastoma
map experimental info protein estimated location
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HEPG2SP_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE PLASMA MASTER GEL [2].
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LIVER_HUMAN {Liver} Homo sapiens (Human)
Tissue: Liver
map experimental info protein estimated location
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LIVER_HUMAN
MAP LOCATIONS:
NORMAL LEVEL: RED CELL CONTAMINATION.
POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
MAPPING (identification): MICROSEQUENCING [1].
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LYMPHOCYTE_HUMAN {Lymphocytes} Homo sapiens (Human)
Tissue: Lymphocyte
map experimental info protein estimated location
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LYMPHOCYTE_HUMAN
MAP LOCATIONS:
NORMAL LEVEL: RED CELL CONTAMINATION.
MAPPING (identification): Peptide mass fingerprinting [9].
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LYMPHOMA_HUMAN {Lymphoma} Homo sapiens (Human)
Tissue: Lymphoma
map experimental info protein estimated location
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LYMPHOMA_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
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PLASMA_HUMAN {Plasma} Homo sapiens (Human)
Tissue: Plasma
map experimental info protein estimated location
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PLASMA_HUMAN
MAP LOCATIONS:
NORMAL LEVEL: RED CELL CONTAMINATION.
POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
MAPPING (identification): IMMUNOBLOTTING [5].
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PLATELET_HUMAN {Platelet} Homo sapiens (Human)
Tissue: Platelet
map experimental info protein estimated location
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PLATELET_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH RBC AND LIVER MASTERS [6].
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RBC_HUMAN {Red blood cells} Homo sapiens (Human)
Tissue: Erythrocyte
map experimental info protein estimated location
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RBC_HUMAN
MAP LOCATIONS:
POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
MAPPING (identification): IMMUNOBLOTTING [3] AND MATCHING [4].
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Copyright |
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). |
Cross-references |
HSC-2DPAGE | P02023; HUMAN. |
PMMA-2DPAGE | P02023. |
REPRODUCTION-2DPAGE | IPI00654755; IPI00654755. |
REPRODUCTION-2DPAGE | P68871; P68871. |
Siena-2DPAGE | P02023. |
UCD-2DPAGE | P68871; HBB_HUMAN. |
UCD-2DPAGE | P02023; P02023. |
UniProtKB/Swiss-Prot | P68871; HBB_HUMAN. |
2D PAGE maps for identified proteins
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- How to interpret a protein map
- You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
- Warning 1: the displayed region reflects
an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information.
It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
- Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
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