World-2DPAGE Home
Home  |  Contact

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.


SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 

Maps  [experimental info] 
[protein list] 
[graphical interface]

     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: HBB_HUMAN




SWISS-2DPAGE: HBB_HUMAN



HBB_HUMAN:

Nice View - a user-friendly view of this entry
ID   HBB_HUMAN; STANDARD; 2DG.
AC   P68871; P02023;
DT   01-AUG-1993, integrated into SWISS-2DPAGE (release 0).
DT   31-MAR-2004, 2D annotation version 4.
DT   19-MAY-2011, general annotation version 16.
DE   RecName: Full=Hemoglobin subunit beta; AltName: Full=Beta-globin;
DE   AltName: Full=Hemoglobin beta chain; Contains: RecName: Full=LVV-hemorphin-7;.
GN   Name=HBB;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Hominidae; Homo.
OX   NCBI_TaxID=9606;
MT   CEC_HUMAN, DLD1_HUMAN, HEPG2_HUMAN, HEPG2SP_HUMAN, LIVER_HUMAN,
MT   LYMPHOCYTE_HUMAN, LYMPHOMA_HUMAN, PLASMA_HUMAN, PLATELET_HUMAN, RBC_HUMAN.
IM   CEC_HUMAN, DLD1_HUMAN, HEPG2_HUMAN, HEPG2SP_HUMAN, LIVER_HUMAN,
IM   LYMPHOCYTE_HUMAN, LYMPHOMA_HUMAN, PLASMA_HUMAN, PLATELET_HUMAN, RBC_HUMAN.
RN   [1]
RP   MAPPING ON GEL.
RX   MEDLINE=93162045; PubMed=1286669; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F.,
RA   Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel
RA   R.D., Hughes G.J.;
RT   ''''''Human liver protein map: a reference database established by
RT   microsequencing and gel comparison'';'';'';
RL   Electrophoresis 13(1):992-1001(1992).
RN   [2]
RP   MAPPING ON GEL.
RX   MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch
RA   A., Hochstrasser D.F.;
RT   ''''''Inside SWISS-2DPAGE database'';'';'';
RL   Electrophoresis 16(1):1131-1151(1995).
RN   [3]
RP   MAPPING ON GEL.
RX   MEDLINE=79188222; PubMed=109131; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Edwards J., Anderson N.G., Nance S.L., Anderson N.L.;
RT   ''''''Red cell proteins. I. Two-dimensional mapping of human erythrocyte
RT   lysate proteins'';'';'';
RL   Blood 53(1):1121-1132(1979).
RN   [4]
RP   MAPPING ON GEL.
RX   MEDLINE=93120196; PubMed=1477117; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Golaz O., Walzer C., Hochstrasser D.F., Bjellqvist B., Turler H., Balant L.P.;
RT   ''''''Red blood cell protein map: a comparison between carrier-ampholyte
RT   pH gradient and immobilized pH gradient, and identification of four red
RT   blood cell enzymes'';'';'';
RL   Appl. Theor. Electrophor. 3(1):77-82(1992).
RN   [5]
RP   MAPPING ON GEL.
RX   MEDLINE=78094420; PubMed=271964; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Anderson N.L., Anderson N.G.;
RT   ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'';
RL   Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977).
RN   [6]
RP   MAPPING ON GEL.
RX   MEDLINE=96007935; PubMed=7498158; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Gravel P., Sanchez J.-C., Walzer C., Golaz O., Hochstrasser D.F., Balant
RA   L.P., Hughes G.J., Garcia-Sevilla J., Guimon J.;
RT   ''''''Human blood platelet protein map established by two-dimensional
RT   polyacrylamide gel electrophoresis'';'';'';
RL   Electrophoresis 16(1):1152-1159(1995).
RN   [7]
RP   MAPPING ON GEL.
RX   MEDLINE=98163346; PubMed=9504818; [NCBI, ExPASy, EBI, Israel, Japan]
RA   Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado
RA   M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F.;
RT   ''''''Standardized characterization of gene expression in human
RT   colorectal epithelium by two-dimensional electrophoresis'';'';'';
RL   Electrophoresis 18(1):2842-2848(1997).
RN   [8]
RP   MAPPING ON GEL.
RA   Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A.,
RA   Appel R.D., Hochstrasser D.F.;
RL   Submitted (JAN-1999) to SWISS-2DPAGE.
RN   [9]
RP   MAPPING ON GEL.
RA   Vuadens F., Crettaz D., Telenti A., Quadroni M., Duchosal M.A., Schneider
RA   P., Tissot J.-D.;
RT   ''''''New insights into HIV lymphocyte infection'';'';'';
RL   (IN) Sanchez J.-C., Corthals G.L., Hochstrasser D.F. (eds.);
RL   Biomedical Application of Proteomics, pp.245-262, Wiley-VCH, Weinheim (2004).
CC   -!- SUBUNIT: ALPHA; BETA 
2D   -!- MASTER: CEC_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000V0U=6.44/11163;
2D   -!-   PI/MW: SPOT 2D-000V2C=6.24/10204;
2D   -!-   MAPPING: MATCHING WITH THE LIVER MASTER GEL AND MICROSEQUENCING [7].
2D   -!- MASTER: DLD1_HUMAN;
2D   -!-   PI/MW: SPOT 2D-001F7L=6.87/12036;
2D   -!-   PI/MW: SPOT 2D-001F7M=6.90/11989;
2D   -!-   MAPPING: MATCHING WITH THE HEPG2 MASTER GEL [8].
2D   -!- MASTER: HEPG2_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0003Y8=6.92/12262;
2D   -!-   PI/MW: SPOT 2D-0003Y9=6.94/12332;
2D   -!-   MAPPING: MATCHING WITH THE LIVER MASTER GEL [2].
2D   -!- MASTER: HEPG2SP_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0009MX=7.81/11823;
2D   -!-   PI/MW: SPOT 2D-0009MY=7.66/11664;
2D   -!-   PI/MW: SPOT 2D-0009MZ=7.74/11770;
2D   -!-   PI/MW: SPOT 2D-0009N5=7.57/11559;
2D   -!-   MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D   -!- MASTER: LIVER_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0001BV=7.08/26002;
2D   -!-   PI/MW: SPOT 2D-0001N0=7.08/12638;
2D   -!-   PI/MW: SPOT 2D-0001NC=6.85/12558;
2D   -!-   PI/MW: SPOT 2D-0001NG=6.71/12747;
2D   -!-   NORMAL LEVEL: RED CELL CONTAMINATION.
2D   -!-   POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
2D   -!-   MAPPING: MICROSEQUENCING [1].
2D   -!- MASTER: LYMPHOCYTE_HUMAN;
2D   -!-   PI/MW: SPOT 2D-001YG0=7.63/16594;
2D   -!-   PI/MW: SPOT 2D-001YG9=7.55/16153;
2D   -!-   PEPTIDE MASSES: SPOT 2D-001YG0: 1126.6138; 1274.7705; 1314.7063;
2D         1378.7344; 1669.9066; 1776.9864; 1797.9638; 2074.9416; TRYPSIN.
2D   -!-   PEPTIDE MASSES: SPOT 2D-001YG9: 1126.5561; 1274.733; 1314.6739;
2D         1669.883; TRYPSIN.
2D   -!-   NORMAL LEVEL: RED CELL CONTAMINATION.
2D   -!-   MAPPING: Peptide mass fingerprinting [9].
2D   -!- MASTER: LYMPHOMA_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0008BY=7.06/12700;
2D   -!-   PI/MW: SPOT 2D-0008C4=6.92/12583;
2D   -!-   MAPPING: MATCHING WITH THE LIVER MASTER GEL [2].
2D   -!- MASTER: PLASMA_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0005I6=7.05/10530;
2D   -!-   PI/MW: SPOT 2D-0005I9=6.88/10530;
2D   -!-   NORMAL LEVEL: RED CELL CONTAMINATION.
2D   -!-   POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
2D   -!-   MAPPING: IMMUNOBLOTTING [5].
2D   -!- MASTER: PLATELET_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000GIU=7.44/12888;
2D   -!-   MAPPING: MATCHING WITH RBC AND LIVER MASTERS [6].
2D   -!- MASTER: RBC_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0006CZ=7.28/26647;
2D   -!-   PI/MW: SPOT 2D-0006DY=8.41/29402;
2D   -!-   PI/MW: SPOT 2D-0006E1=7.94/29102;
2D   -!-   PI/MW: SPOT 2D-0006E3=8.42/28865;
2D   -!-   PI/MW: SPOT 2D-0006ER=7.93/28570;
2D   -!-   PI/MW: SPOT 2D-0006F0=8.41/28221;
2D   -!-   PI/MW: SPOT 2D-0006F7=7.62/28106;
2D   -!-   PI/MW: SPOT 2D-0006FB=7.96/28048;
2D   -!-   PI/MW: SPOT 2D-0006FV=8.41/27762;
2D   -!-   PI/MW: SPOT 2D-0006GE=6.99/27311;
2D   -!-   PI/MW: SPOT 2D-0006GF=7.65/27143;
2D   -!-   PI/MW: SPOT 2D-0006GJ=6.94/27199;
2D   -!-   PI/MW: SPOT 2D-0006GM=7.92/27199;
2D   -!-   PI/MW: SPOT 2D-0006H4=6.88/26593;
2D   -!-   PI/MW: SPOT 2D-0006H5=8.37/26702;
2D   -!-   PI/MW: SPOT 2D-0006H7=6.94/26593;
2D   -!-   PI/MW: SPOT 2D-0006HA=7.93/26647;
2D   -!-   PI/MW: SPOT 2D-0006HC=7.00/26484;
2D   -!-   PI/MW: SPOT 2D-0006HE=7.63/26322;
2D   -!-   PI/MW: SPOT 2D-0006HQ=8.35/26322;
2D   -!-   PI/MW: SPOT 2D-0006HW=6.93/25641;
2D   -!-   PI/MW: SPOT 2D-0006I7=8.39/25743;
2D   -!-   PI/MW: SPOT 2D-0006IG=7.92/25590;
2D   -!-   PI/MW: SPOT 2D-0006IK=7.62/25437;
2D   -!-   PI/MW: SPOT 2D-0006IR=8.38/25086;
2D   -!-   PI/MW: SPOT 2D-0006IX=7.89/25036;
2D   -!-   PI/MW: SPOT 2D-0006J1=7.58/24936;
2D   -!-   PI/MW: SPOT 2D-0006PE=7.03/14177;
2D   -!-   PI/MW: SPOT 2D-0006Q2=7.56/14177;
2D   -!-   PI/MW: SPOT 2D-0006Q7=8.75/13486;
2D   -!-   PI/MW: SPOT 2D-0006QE=7.86/13152;
2D   -!-   PI/MW: SPOT 2D-0006QU=6.93/12756;
2D   -!-   PI/MW: SPOT 2D-0006QV=8.38/13007;
2D   -!-   PI/MW: SPOT 2D-0006QZ=8.24/13448;
2D   -!-   PI/MW: SPOT 2D-0006R3=6.80/12899;
2D   -!-   PI/MW: SPOT 2D-0006R7=7.31/12756;
2D   -!-   PI/MW: SPOT 2D-0006RK=6.65/12721;
2D   -!-   PI/MW: SPOT 2D-0006RP=6.58/12721;
2D   -!-   PI/MW: SPOT 2D-0006RW=6.52/12651;
2D   -!-   PI/MW: SPOT 2D-0006S4=6.45/12580;
2D   -!-   POSITIONAL VARIANTS: MULTITUDE OF GENETIC VARIANTS.
2D   -!-   MAPPING: IMMUNOBLOTTING [3] AND MATCHING [4].
CC   ---------------------------------------------------------------------------
CC   This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics.
CC   There are no restrictions on its use by non-profit institutions as long as
CC   its content is in no way modified and this statement is not removed.
CC   Usage by and for commercial entities requires a license agreement (See
CC   http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
CC   ---------------------------------------------------------------------------
DR   HSC-2DPAGE; P02023; HUMAN.
DR   PMMA-2DPAGE; P02023.
DR   REPRODUCTION-2DPAGE; IPI00654755; IPI00654755.
DR   REPRODUCTION-2DPAGE; P68871; P68871.
DR   Siena-2DPAGE; P02023.
DR   UCD-2DPAGE; P68871; HBB_HUMAN.
DR   UCD-2DPAGE; P02023; P02023.
DR   UniProtKB/Swiss-Prot; P68871; HBB_HUMAN.
//


The following 2-D maps are available for this protein:
Colorectal epithelia cells
CEC_HUMAN
Colorectal adenocarcinoma cell line (DL-1)
DLD1_HUMAN
HepG2
HEPG2_HUMAN
HepG2 Secreted Proteins
HEPG2SP_HUMAN
Liver
LIVER_HUMAN
Lymphocytes
LYMPHOCYTE_HUMAN
Lymphoma
LYMPHOMA_HUMAN
Plasma
PLASMA_HUMAN
Platelet
PLATELET_HUMAN
Red blood cells
RBC_HUMAN
  


SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server