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Sample Preparation and Post-separation Analysis Searching in 'SWISS-2DPAGE' for entry matching: HSP7C_HUMAN SWISS-2DPAGE:  HSP7C_HUMAN HSP7C_HUMAN General information about the entry View entry in simple text format Entry name HSP7C_HUMAN Primary accession number P11142 integrated into SWISS-2DPAGE on  January 15, 1999 (release 9) 2D Annotations were last modified on May 15, 2003 (version 3) General Annotations were last modified on  May 19, 2011 (version 12) Name and origin of the protein Description RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8;. Gene name Name=HSPA8 Synonyms=HSC70, HSP73, HSPA10 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   MAPPING ON GEL Demalte-Annessi I., Sanchez J.-C., Hoogland C., Rouge V., Binz P.-A., Appel R.D., Hochstrasser D.F. Submitted (JAN-1999) to SWISS-2DPAGE [2]   MAPPING ON GEL MEDLINE=20529951; PubMed=11079567; [NCBI, Expasy, EBI, Israel, Japan] Jung E., Hoogland C., Chiappe D., Sanchez J.-C., Hochstrasser D.F. ''''''The establishment of a human liver nuclei 2-DE reference map'';'';'' Electrophoresis 21(1):3483-3487(2000) [3]   MAPPING ON GEL PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan] Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J. ''''''Functional proteomic analysis of human nucleolus'';'';'' Mol. Biol. Cell. 13(1):4100-4109(2002) 2D PAGE maps for identified proteins How to interpret a protein DLD1_HUMAN {Colorectal adenocarcinoma cell line (DL-1)} Homo sapiens (Human) Tissue: Colon adenocarcinoma   map experimental info   protein estimated location   DLD1_HUMAN MAP LOCATIONS: SPOT 2D-001DK7: pI=5.17; Mw=69894   [identification data] MAPPING (identification): Peptide mass fingerprinting [1]. NUCLEI_LIVER_HUMAN {Soluble nuclear proteins and matrix from liver tissue} Homo sapiens (Human) Tissue: Liver   map experimental info   protein estimated location   NUCLEI_LIVER_HUMAN MAP LOCATIONS: SPOT 2D-001J00: pI=5.39; Mw=67478   [identification data] SPOT 2D-001J03: pI=5.31; Mw=67478   [identification data] MAPPING (identification): Peptide mass fingerprinting [2]. NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells} Homo sapiens (Human) Tissue: Cervix carcinoma   map experimental info   protein estimated location   NUCLEOLI_HELA_2D_HUMAN MAP LOCATIONS: SPOT 2D-001VGX: pI=5.50; Mw=70432   [identification data] MAPPING (identification): Peptide mass fingerprinting and tandem mass spectrometry [3]. Copyright This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). Cross-references DOSAC-COBS 2D-PAGE P11142; P11142. DOSAC-COBS-2DPAGE P11142; HSP7C_HUMAN. HSC-2DPAGE P11142; HUMAN. OGP-WWW P11142. PHCI-2DPAGE P11142; HS7C_HUMAN. REPRODUCTION-2DPAGE IPI00003865; IPI00003865. Siena-2DPAGE P11142; HSP7C_HUMAN. UCD-2DPAGE P11142; HSP7C_HUMAN. UniProtKB/Swiss-Prot P11142; HSP7C_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 2011_10 Entry name HSP7C_HUMAN Primary accession number P11142 Secondary accession number(s) Q9H3R6 Sequence was last modified on  July 1, 1989 (version 1) Annotations were last modified on  October 19, 2011 (version 150) Name and origin of the protein Description RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8; Gene name Name=HSPA8 Synonyms=HSC70, HSP73, HSPA10 Encoded on Name=HSPA8; Synonyms=HSC70, HSP73, HSPA10 Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Host-virus interaction; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Repressor; Stress response; Transcription; Transcription regulation; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y00371; CAA68445.1; -; Genomic_DNA EMBL AB034951; BAB18615.1; -; mRNA EMBL AF352832; AAK17898.1; -; mRNA EMBL BC016179; AAH16179.1; -; mRNA EMBL BC016660; AAH16660.1; -; mRNA EMBL BC019816; AAH19816.1; -; mRNA IPI IPI00003865; -; . IPI IPI00037070; -; . PIR A27077; A27077; . RefSeq NP_006588.1; NM_006597.4; . RefSeq NP_694881.1; NM_153201.2; . UniGene Hs.180414; -; . PDB 3AGY; X-ray; 1.85 A; C/D/F=639-646 PDB 3AGZ; X-ray; 2.51 A; C/D/E/F=639-646 PDB 3ESK; X-ray; 2.05 A; B=635-646 PDB 3FZF; X-ray; 2.20 A; A=4-381 PDB 3FZH; X-ray; 2.00 A; A=4-381 PDB 3FZK; X-ray; 2.10 A; A=4-381 PDB 3FZL; X-ray; 2.20 A; A=4-381 PDB 3FZM; X-ray; 2.30 A; A=4-381 PDB 3LDQ; X-ray; 1.90 A; A=4-381 PDB 3M3Z; X-ray; 2.10 A; A=4-381 PDBsum 3AGY; -; . PDBsum 3AGZ; -; . PDBsum 3ESK; -; . PDBsum 3FZF; -; . PDBsum 3FZH; -; . PDBsum 3FZK; -; . PDBsum 3FZL; -; . PDBsum 3FZM; -; . PDBsum 3LDQ; -; . PDBsum 3M3Z; -; . ProteinModelPortal P11142; -; . SMR P11142; 1-621; . IntAct P11142; 45; . MINT MINT-4998609; -; . STRING P11142; -; . PhosphoSite P11142; -; . SWISS-2DPAGE P11142; -; . Aarhus/Ghent-2DPAGE 6504; IEF; . Cornea-2DPAGE P11142; -; . DOSAC-COBS-2DPAGE P11142; -; . OGP P11142; -; . PHCI-2DPAGE P11142; -; . REPRODUCTION-2DPAGE IPI00003865; -; . UCD-2DPAGE P11142; -; . PeptideAtlas P11142; -; . PRIDE P11142; -; . Ensembl ENST00000227378; ENSP00000227378; ENSG00000109971; . GeneID 3312; -; . KEGG hsa:3312; -; . UCSC uc001pyo.1; human; . UCSC uc001pyp.1; human; . CTD 3312; -; . GeneCards GC11M118870; -; . H-InvDB HIX0010213; -; . HGNC HGNC:5241; HSPA8; . HPA CAB002056; -; . MIM 600816; gene; . neXtProt NX_P11142; -; . PharmGKB PA29507; -; . eggNOG prNOG17884; -; . HOGENOM HBG334976; -; . HOVERGEN HBG051845; -; . InParanoid P11142; -; . OMA HQQKDLE; -; . OrthoDB EOG4W6NVK; -; . PhylomeDB P11142; -; . Pathway_Interaction_DB smad2_3nuclearpathway; Regulation of nuclear SMAD2/3 signaling; . Reactome REACT_11123; Membrane Trafficking; . Reactome REACT_13685; Synaptic Transmission; . Reactome REACT_21257; Metabolism of RNA; . NextBio 13136; -; . PMAP-CutDB P11142; -; . CleanEx HS_HSPA8; -; . Genevestigator P11142; -; . GermOnline ENSG00000109971; Homo sapiens; . GO GO:0009986; C:cell surface; IDA:UniProtKB; . GO GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0042623; F:ATPase activity; coupled; NAS:UniProtKB GO GO:0005515; F:protein binding; IPI:UniProtKB; . GO GO:0016044; P:cellular membrane organization; TAS:Reactome; . GO GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW; . GO GO:0016071; P:mRNA metabolic process; TAS:Reactome; . GO GO:0045892; P:negative regulation of transcription; DNA-dependent; IDA:UniProtKB GO GO:0007269; P:neurotransmitter secretion; TAS:Reactome; . GO GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0006457; P:protein folding; NAS:UniProtKB; . GO GO:0006986; P:response to unfolded protein; NAS:UniProtKB; . GO GO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW InterPro IPR018181; Heat_shock_70_CS; . InterPro IPR001023; Hsp70; . InterPro IPR013126; Hsp_70; . PANTHER PTHR19375; Hsp70; 1; . Pfam PF00012; HSP70; 1; . PRINTS PR00301; HEATSHOCK70; . PROSITE PS00297; HSP70_1; 1; . PROSITE PS00329; HSP70_2; 1; . PROSITE PS01036; HSP70_3; 1; . SWISS-2DPAGE (search AC)