Attention: World-2DPAGE is no longer maintained.

RecName: Full=Epoxide hydrolase 2; EC=3.3.2.10; AltName: Full=Cytosolic epoxide hydrolase; Short=CEH; AltName: Full=Epoxide hydratase; AltName: Full=Soluble epoxide hydrolase; Short=SEH;.

Gene name

Name=Ephx2
Synonyms=Eph2

Annotated species

Mus musculus (Mouse) [TaxID: 10090]

Taxonomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.

References

[1]

MAPPING ON GEL
PubMed=11680894; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)

2D PAGE maps for identified proteins

How to interpret a protein

LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver

map experimental info
protein estimated location

LIVER_MOUSE

MAP LOCATIONS:

SPOT 2D-0013AO:

pI=6.36; Mw=57678

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright

This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).

Cross-references

UniProtKB/Swiss-Prot

P34914; HYES_MOUSE.

2D PAGE maps for identified proteins

How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry name	HYES_MOUSE
Primary accession number	P34914
Secondary accession number(s)	Q8CGV0
Sequence was last modified on	October 1, 1996 (version 2)
Annotations were last modified on	September 21, 2011 (version 109)
Name and origin of the protein
Description	RecName: Full=Epoxide hydrolase 2; EC=3.3.2.10; AltName: Full=Cytosolic epoxide hydrolase; Short=CEH; AltName: Full=Epoxide hydratase; AltName: Full=Soluble epoxide hydrolase; Short=SEH;
Gene name	Name=Ephx2 Synonyms=Eph2
Encoded on	Name=Ephx2; Synonyms=Eph2
Keywords	3D-structure; Alternative splicing; Aromatic hydrocarbons catabolism; Complete proteome; Cytoplasm; Detoxification; Direct protein sequencing; Hydrolase; Lipoprotein; Magnesium; Metal-binding; Peroxisome; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL	L05781; AAA37555.1; -; mRNA
EMBL	Z37107; CAA85471.1; -; mRNA
EMBL	AY098585; AAM28238.1; -; mRNA
EMBL	BC015087; AAH15087.1; -; mRNA
IPI	IPI00321617; -; .
IPI	IPI00407606; -; .
PIR	A47504; A47504; .
RefSeq	NP_031966.2; NM_007940.3; .
UniGene	Mm.15295; -; .
PDB	1CQZ; X-ray; 2.80 A; A/B=1-554
PDB	1CR6; X-ray; 2.80 A; A/B=1-554
PDB	1EK1; X-ray; 3.10 A; A/B=1-554
PDB	1EK2; X-ray; 3.00 A; A/B=1-554
PDBsum	1CQZ; -; .
PDBsum	1CR6; -; .
PDBsum	1EK1; -; .
PDBsum	1EK2; -; .
ProteinModelPortal	P34914; -; .
SMR	P34914; 4-544; .
STRING	P34914; -; .
MEROPS	S33.973; -; .
PhosphoSite	P34914; -; .
SWISS-2DPAGE	P34914; -; .
PRIDE	P34914; -; .
Ensembl	ENSMUST00000070515; ENSMUSP00000069209; ENSMUSG00000022040; .
Ensembl	ENSMUST00000111128; ENSMUSP00000106758; ENSMUSG00000022040; .
GeneID	13850; -; .
KEGG	mmu:13850; -; .
UCSC	uc007ujw.1; mouse; .
CTD	2053; -; .
MGI	MGI:99500; Ephx2; .
eggNOG	roNOG04197; -; .
GeneTree	ENSGT00530000063213; -; .
HOGENOM	HBG507108; -; .
HOVERGEN	HBG006095; -; .
InParanoid	P34914; -; .
OMA	NNWLDDS; -; .
OrthoDB	EOG45QHCT; -; .
PhylomeDB	P34914; -; .
BRENDA	3.3.2.10; 3474; .
NextBio	284704; -; .
ArrayExpress	P34914; -; .
Bgee	P34914; -; .
CleanEx	MM_EPHX2; -; .
Genevestigator	P34914; -; .
GermOnline	ENSMUSG00000022040; Mus musculus; .
GO	GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell; .
GO	GO:0004301; F:epoxide hydrolase activity; IEA:EC; .
GO	GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; .
GO	GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW; .
GO	GO:0009636; P:response to toxin; IEA:UniProtKB-KW; .
InterPro	IPR000073; AB_hydrolase_1; .
InterPro	IPR005834; Dehalogen-like_hydro; .
InterPro	IPR000639; Epox_hydrolase-like; .
InterPro	IPR023214; HAD-like_dom; .
InterPro	IPR006402; HAD-SF_hydro_IA_v3; .
Gene3D	G3DSA:3.40.50.1000; HAD-like_dom; 1; .
Pfam	PF00561; Abhydrolase_1; 1; .
Pfam	PF00702; Hydrolase; 1; .
PRINTS	PR00111; ABHYDROLASE; .
PRINTS	PR00412; EPOXHYDRLASE; .
SUPFAM	SSF56784; HAD-like_dom; 1; .
TIGRFAMs	TIGR01509; HAD-SF-IA-v3; 1; .

SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server