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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: IGHG_HUMAN




SWISS-2DPAGE:  IGHG_HUMAN


IGHG_HUMAN


General information about the entry
View entry in simple text format
Entry nameIGHG_HUMAN
Primary accession numberP99006
integrated into SWISS-2DPAGE on August 1, 1993 (release 0)
2D Annotations were last modified onDecember 1, 2000 (version 1)
General Annotations were last modified on December 1, 2000 (version 7)
Name and origin of the protein
DescriptionImmunoglobulin heavy chain gamma.
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
MEDLINE=78094420; PubMed=271964; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Anderson N.G.
''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';''
Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977)
[2]   MAPPING ON GEL
MEDLINE=96007934; PubMed=7498157; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F.
''''''Inside SWISS-2DPAGE database'';'';''
Electrophoresis 16(1):1131-1151(1995)
2D PAGE maps for identified proteins
How to interpret a protein

CSF_HUMAN {Cerebrospinal Fluid}
Homo sapiens (Human)
Tissue: Cerebrospinal fluid
CSF_HUMAN
  map experimental info
  protein estimated location
 
CSF_HUMAN

MAP LOCATIONS:
pI=7.17; Mw=55193
pI=7.04; Mw=54913
pI=7.33; Mw=55475
pI=6.91; Mw=54773
pI=6.76; Mw=54495
pI=6.57; Mw=54080
pI=6.27; Mw=53260
pI=6.31; Mw=53260
pI=6.83; Mw=51921
pI=7.49; Mw=52453
pI=7.03; Mw=51789
pI=7.18; Mw=51789
pI=7.32; Mw=51921
pI=7.70; Mw=51657
pI=7.99; Mw=51921
pI=8.10; Mw=52990
pI=8.27; Mw=52186
pI=6.36; Mw=52990
pI=6.41; Mw=52186
pI=6.51; Mw=51921
pI=6.90; Mw=51657
pI=6.24; Mw=52319
pI=6.45; Mw=52319
pI=6.61; Mw=51657
pI=6.35; Mw=51921
pI=6.31; Mw=51789

MAPPING (identification):
MATCHING WITH THE PLASMA MASTER GEL [2].



PLASMA_HUMAN {Plasma}
Homo sapiens (Human)
Tissue: Plasma
PLASMA_HUMAN
  map experimental info
  protein estimated location
 
PLASMA_HUMAN

MAP LOCATIONS:
pI=6.80; Mw=112014
pI=6.66; Mw=112014
pI=6.59; Mw=109656
pI=7.00; Mw=108112
pI=7.04; Mw=108882
pI=7.14; Mw=108882
pI=7.35; Mw=109656
pI=6.86; Mw=110437
pI=6.95; Mw=110437
pI=7.51; Mw=108882
pI=6.72; Mw=109656
pI=7.74; Mw=107348
pI=6.53; Mw=105837
pI=6.66; Mw=105837
pI=6.51; Mw=105837
pI=6.85; Mw=105837
pI=7.92; Mw=100712
pI=6.60; Mw=103609
pI=6.78; Mw=105089
pI=6.94; Mw=103609
pI=6.73; Mw=105089
pI=7.36; Mw=100712
pI=7.04; Mw=100000
pI=6.67; Mw=101428
pI=6.73; Mw=101428
pI=6.78; Mw=101428
pI=6.85; Mw=100712
pI=7.17; Mw=99619
pI=7.53; Mw=98862
pI=7.74; Mw=99240
pI=6.94; Mw=98862
pI=7.36; Mw=96995
pI=7.04; Mw=96258
pI=7.18; Mw=96626
pI=6.94; Mw=96258
pI=6.55; Mw=54804
pI=6.86; Mw=54655
pI=6.98; Mw=54359
pI=7.15; Mw=54507
pI=7.68; Mw=54507
pI=7.45; Mw=54507
pI=7.93; Mw=54507
pI=8.33; Mw=54804
pI=6.68; Mw=54507
pI=8.08; Mw=54507
pI=8.23; Mw=54655
pI=6.76; Mw=54359
pI=6.36; Mw=53336
pI=6.28; Mw=53336
pI=6.32; Mw=53191
pI=7.50; Mw=51068
pI=7.71; Mw=51347
pI=6.15; Mw=52617
pI=6.46; Mw=52617
pI=6.52; Mw=52617
pI=6.86; Mw=50930
pI=7.17; Mw=51068
pI=8.10; Mw=52190
pI=6.24; Mw=52617
pI=6.43; Mw=51486
pI=6.49; Mw=51207
pI=7.99; Mw=51207
pI=8.35; Mw=51486
pI=8.63; Mw=51626
pI=8.83; Mw=51767
pI=9.02; Mw=51907
pI=6.28; Mw=51767
pI=6.35; Mw=52474
pI=6.41; Mw=51486
pI=6.68; Mw=51068
pI=6.99; Mw=50930
pI=8.24; Mw=51207
pI=8.54; Mw=51626
pI=6.54; Mw=51207
pI=6.76; Mw=50792
pI=6.32; Mw=51626
pI=6.15; Mw=51767
pI=6.24; Mw=51486
pI=6.36; Mw=51207
pI=6.33; Mw=50654

NORMAL LEVEL:
8000-18000 MG/L.

PATHOLOGICAL LEVEL:
DECREASED DURING ANTIBODY DEFICIENCY SYNDROME; INCREASED DURING CHRONIC INFECTIONS, LIVER DISEASES AND IGA MYELOMA.

MAPPING (identification):
IMMUNOBLOTTING [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server