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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: K1C18_MOUSE




SWISS-2DPAGE:  K1C18_MOUSE


K1C18_MOUSE


General information about the entry
View entry in simple text format
Entry nameK1C18_MOUSE
Primary accession numberP05784
integrated into SWISS-2DPAGE on September 1, 1998 (release 7)
2D Annotations were last modified onOctober 1, 2001 (version 2)
General Annotations were last modified on May 19, 2011 (version 10)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type I cytoskeletal 18; AltName: Full=Cytokeratin endo B; Short=Keratin D; AltName: Full=Cytokeratin-18; Short=CK-18; AltName: Full=Keratin-18; Short=K18;.
Gene nameName=Krt18
Synonyms=Kerd, Krt1-18
Annotated speciesMus musculus (Mouse) [TaxID: 10090]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
References
[1]   MAPPING ON GEL
MEDLINE=96154592; PubMed=8586073; [NCBI, ExPASy, EBI, Israel, Japan]
Anderson N.L., Esquer-Blasco R., Hoffmann J.-P., Meheus L., Raymackers J., Steiner S., Witzmann F., Anderson N.G.
''''''An updated two-dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies'';'';''
Electrophoresis 16(1):1977-1981(1995)
[2]   MAPPING ON GEL
MEDLINE=93162044; PubMed=1286668; [NCBI, ExPASy, EBI, Israel, Japan]
Giometti C.S., Taylor J., Tollaksen S.L.
''''''Mouse liver protein database: a catalog of proteins detected by two- dimensional gel electrophoresis'';'';''
Electrophoresis 13(1):970-991(1992)
[3]   MAPPING ON GEL
PubMed=11680894; [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez J.-C., Chiappe D., Converset V., Hoogland C., Binz P.-A., Paesano S., Appel R.D., Wang S., Sennitt M., Nolan A., Cawthorne M.A., Hochstrasser D.F.
''''''The mouse SWISS-2DPAGE database: a tool for proteomics study of diabetes and obesity'';'';''
Proteomics 1(1):136-163(2001)
2D PAGE maps for identified proteins
How to interpret a protein

ISLETS_MOUSE {Pancreatic islet cells}
Mus musculus (Mouse)
Tissue: Pancreatic islet
ISLETS_MOUSE
  map experimental info
  protein estimated location
 
ISLETS_MOUSE

MAP LOCATIONS:
pI=5.12; Mw=48613  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [3].



LIVER_MOUSE {Liver}
Mus musculus (Mouse)
Tissue: Liver
LIVER_MOUSE
  map experimental info
  protein estimated location
 
LIVER_MOUSE

MAP LOCATIONS:
pI=5.15; Mw=46684
pI=5.21; Mw=46684
pI=5.26; Mw=46554

MAPPING (identification):
MATCHING [3] WITH ANDERSON MOUSE AND RAT LIVER 2-DE MAPS [1], AND WITH GIOMETTI MOUSE LIVER 2-DE MAP [2].



NUCLEI_LIVER_MOUSE {Soluble nuclear proteins and matrix from liver tissue}
Mus musculus (Mouse)
Tissue: Liver
NUCLEI_LIVER_MOUSE
  map experimental info
  protein estimated location
 
NUCLEI_LIVER_MOUSE

MAP LOCATIONS:
pI=5.21; Mw=46131  [identification data]
pI=5.00; Mw=45881  [identification data]
pI=5.06; Mw=45633  [identification data]
pI=4.74; Mw=15127  [identification data]

MAPPING (identification):
Peptide mass fingerprinting [3].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtP05784; K1C18_MOUSE.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameK1C18_MOUSE
Primary accession numberP05784
Secondary accession number(s) Q3TIX1 Q3TJH6 Q3TJW7 Q61766
Sequence was last modified on May 29, 2007 (version 5)
Annotations were last modified on September 21, 2011 (version 104)
Name and origin of the protein
DescriptionRecName: Full=Keratin, type I cytoskeletal 18; AltName: Full=Cytokeratin endo B; Short=Keratin D; AltName: Full=Cytokeratin-18; Short=CK-18; AltName: Full=Keratin-18; Short=K18;
Gene nameName=Krt18
Synonyms=Kerd, Krt1-18
Encoded onName=Krt18; Synonyms=Kerd, Krt1-18
KeywordsAcetylation; Coiled coil; Complete proteome; Glycoprotein; Intermediate filament; Keratin; Phosphoprotein; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM11686; AAA39390.1; -; mRNA
EMBLM36376; AAA39373.1; -; mRNA
EMBLM22832; AAA37552.1; -; Genomic_DNA
EMBLAK145413; BAE26424.1; -; mRNA
EMBLAK167072; BAE39232.1; -; mRNA
EMBLAK167265; BAE39378.1; -; mRNA
EMBLAK167432; BAE39519.1; -; mRNA
EMBLAK167469; BAE39553.1; -; mRNA
EMBLAK167676; BAE39725.1; -; mRNA
EMBLBC089022; AAH89022.1; -; mRNA
EMBLY00217; CAA68365.1; -; Genomic_DNA
IPIIPI00311493; -; .
PIRI59463; I59463; .
RefSeqNP_034794.2; NM_010664.2; .
UniGeneMm.22479; -; .
ProteinModelPortalP05784; -; .
SMRP05784; 70-106; 114-220; 237-382
STRINGP05784; -; .
PhosphoSiteP05784; -; .
SWISS-2DPAGEP05784; -; .
PRIDEP05784; -; .
EnsemblENSMUST00000023803; ENSMUSP00000023803; ENSMUSG00000023043; .
GeneID16668; -; .
KEGGmmu:16668; -; .
UCSCuc007xuj.2; mouse; .
CTD3875; -; .
MGIMGI:96692; Krt18; .
eggNOGroNOG07151; -; .
GeneTreeENSGT00560000076905; -; .
HOGENOMHBG715391; -; .
HOVERGENHBG013015; -; .
InParanoidP05784; -; .
OMAKGLQNQI; -; .
OrthoDBEOG4RV2S1; -; .
PhylomeDBP05784; -; .
NextBio290387; -; .
ArrayExpressP05784; -; .
BgeeP05784; -; .
CleanExMM_KRT18; -; .
GenevestigatorP05784; -; .
GermOnlineENSMUSG00000023043; Mus musculus; .
GOGO:0005515; F:protein binding; IPI:MGI; .
GOGO:0005198; F:structural molecule activity; IEA:InterPro; .
GOGO:0006915; P:apoptosis; IMP:MGI; .
GOGO:0033209; P:tumor necrosis factor-mediated signaling pathway; IGI:MGI; .
InterProIPR016044; F; .
InterProIPR001664; IF; .
InterProIPR018039; Intermediate_filament_CS; .
InterProIPR002957; Keratin_I; .
PANTHERPTHR23239; IF; 1; .
PfamPF00038; Filament; 1; .
PRINTSPR01248; TYPE1KERATIN; .
PROSITEPS00226; IF; 1; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server