General information about the entry |
View entry in simple text format |
Entry name | KCY_HUMAN |
Primary accession number | P30085 |
integrated into SWISS-2DPAGE on | August 1, 1993 (release 0) |
2D Annotations were last modified on | March 31, 2004 (version 2) |
General Annotations were last modified on | May 19, 2011 (version 16) |
Name and origin of the protein |
Description | RecName: Full=UMP-CMP kinase; EC=2.7.4.14; AltName: Full=Cytidine monophosphate kinase; AltName: Full=Cytidylate kinase; AltName: Full=Deoxycytidylate kinase; AltName: Full=Uridine monophosphate kinase; AltName: Full=Uridine monophosphate/cytidine monophosphate kinase; Short=UMP/CMP kinase; Short=UMP/CMPK;. |
Gene name | Name=CMPK1 Synonyms=CMK, CMPK, UCK, UMK, UMPK
|
Annotated species | Homo sapiens (Human) [TaxID: 9606] |
Taxonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
References |
[1] |
MAPPING ON GEL MEDLINE=93162045; PubMed=1286669; [NCBI, Expasy, EBI, Israel, Japan]
Hochstrasser D.F., Frutiger S., Paquet N., Bairoch A., Ravier F., Pasquali C., Sanchez J.-C., Tissot J.-D., Bjellqvist B., Vargas R., Appel R.D., Hughes G.J. ''''''Human liver protein map: a reference database established by microsequencing and gel comparison'';'';'' Electrophoresis 13(1):992-1001(1992)
|
[2] |
MAPPING ON GEL MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch A., Hochstrasser D.F. ''''''Inside SWISS-2DPAGE database'';'';'' Electrophoresis 16(1):1131-1151(1995)
|
[3] |
MAPPING ON GEL MEDLINE=98163346; PubMed=9504818; [NCBI, Expasy, EBI, Israel, Japan]
Reymond M.A., Sanchez J.-C., Hughes G.J., Riese J., Tortola S., Peinado M.A., Kirchner T., Hohenberger W., Hochstrasser D.F., Kockerling F. ''''''Standardized characterization of gene expression in human colorectal epithelium by two-dimensional electrophoresis'';'';'' Electrophoresis 18(1):2842-2848(1997)
|
|
2D PAGE maps for identified proteins
|
How to interpret a protein
|
CEC_HUMAN {Colorectal epithelia cells} Homo sapiens (Human)
Tissue: Colon epithelium
map experimental info protein estimated location
|
|
CEC_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL AND MICROSEQUENCING [3].
|
ELC_HUMAN {Erythroleukemia Cell} Homo sapiens (Human)
Tissue: Erythroleukemia
map experimental info protein estimated location
|
|
ELC_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
|
HEPG2_HUMAN {HepG2} Homo sapiens (Human)
Tissue: Hepatoblastoma
map experimental info protein estimated location
|
|
HEPG2_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
|
LIVER_HUMAN {Liver} Homo sapiens (Human)
Tissue: Liver
map experimental info protein estimated location
|
|
LIVER_HUMAN
MAP LOCATIONS:
MAPPING (identification): MICROSEQUENCING [1].
|
LYMPHOMA_HUMAN {Lymphoma} Homo sapiens (Human)
Tissue: Lymphoma
map experimental info protein estimated location
|
|
LYMPHOMA_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
|
U937_HUMAN {Macrophage Like Cell Line} Homo sapiens (Human)
Tissue: Histiocytic lymphoma
map experimental info protein estimated location
|
|
U937_HUMAN
MAP LOCATIONS:
MAPPING (identification): MATCHING WITH THE LIVER MASTER GEL [2].
|
Copyright |
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss). |
Cross-references |
OGP-WWW | P30085. |
Siena-2DPAGE | P30085; KCY_HUMAN. |
UniProtKB/Swiss-Prot | P30085; KCY_HUMAN. |
2D PAGE maps for identified proteins
|
- How to interpret a protein map
- You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
- Warning 1: the displayed region reflects
an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information.
It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
- Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
|
External data extracted from UniProtKB/Swiss-Prot |
Extracted from UniProtKB/Swiss-Prot, release: 2011_10 |
Entry name | KCY_HUMAN |
Primary accession number | P30085 |
Secondary accession number(s) | Q53GB7 Q5SVZ0 Q96C07 Q9UBQ8 Q9UIA2 |
Sequence was last modified on | December 1, 2000 (version 3) |
Annotations were last modified on | October 19, 2011 (version 123) |
Name and origin of the protein |
Description | RecName: Full=UMP-CMP kinase; EC=2.7.4.14; AltName: Full=Cytidine monophosphate kinase; AltName: Full=Cytidylate kinase; AltName: Full=Deoxycytidylate kinase; AltName: Full=Uridine monophosphate kinase; AltName: Full=Uridine monophosphate/cytidine monophosphate kinase; Short=UMP/CMP kinase; Short=UMP/CMPK; |
Gene name | Name=CMPK1 Synonyms=CMK, CMPK, UCK, UMK, UMPK |
Encoded on | Name=CMPK1; Synonyms=CMK, CMPK, UCK, UMK, UMPK |
Keywords | 3D-structure; Acetylation; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Kinase; Nucleotide-binding; Nucleus; Pyrimidine biosynthesis; Reference proteome; Transferase. |
Copyright |
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License |
Cross-references |
EMBL | AF070416; AAF17709.1; ALT_INIT; mRNA |
EMBL | AF259961; AAG22609.1; -; mRNA |
EMBL | AF110643; AAD48583.1; -; mRNA |
EMBL | AF087865; AAP97174.1; -; mRNA |
EMBL | AF112216; AAF17204.1; -; mRNA |
EMBL | AK223014; BAD96734.1; ALT_INIT; mRNA |
EMBL | AL513322; CAI13471.1; ALT_SEQ; Genomic_DNA |
EMBL | AL607122; CAI13471.1; JOINED; Genomic_DNA |
EMBL | AL607122; CAI14972.1; ALT_SEQ; Genomic_DNA |
EMBL | AL513322; CAI14972.1; JOINED; Genomic_DNA |
EMBL | BC014961; AAH14961.1; ALT_INIT; mRNA |
IPI | IPI00219953; -; . |
PIR | B45482; B45482; . |
RefSeq | NP_001129612.1; NM_001136140.1; . |
RefSeq | NP_057392.1; NM_016308.2; . |
UniGene | Hs.727554; -; . |
PDB | 1TEV; X-ray; 2.10 A; A=1-196 |
PDBsum | 1TEV; -; . |
ProteinModelPortal | P30085; -; . |
SMR | P30085; 3-196; . |
MINT | MINT-5000978; -; . |
STRING | P30085; -; . |
PhosphoSite | P30085; -; . |
SWISS-2DPAGE | P30085; -; . |
OGP | P30085; -; . |
Siena-2DPAGE | P30085; -; . |
PRIDE | P30085; -; . |
Ensembl | ENST00000371873; ENSP00000360939; ENSG00000162368; . |
GeneID | 51727; -; . |
KEGG | hsa:51727; -; . |
UCSC | uc001cri.1; human; . |
CTD | 51727; -; . |
HGNC | HGNC:18170; CMPK1; . |
MIM | 191710; gene; . |
neXtProt | NX_P30085; -; . |
eggNOG | prNOG09408; -; . |
GeneTree | ENSGT00390000016215; -; . |
HOVERGEN | HBG108060; -; . |
InParanoid | P30085; -; . |
BioCyc | MetaCyc:HS08663-MONOMER; -; . |
BRENDA | 2.7.4.14; 2681; . |
Reactome | REACT_1698; Metabolism of nucleotides; . |
DrugBank | DB00441; Gemcitabine; . |
NextBio | 55784; -; . |
ArrayExpress | P30085; -; . |
Bgee | P30085; -; . |
CleanEx | HS_CMPK1; -; . |
Genevestigator | P30085; -; . |
GO | GO:0005829; C:cytosol; TAS:Reactome; . |
GO | GO:0005634; C:nucleus; TAS:ProtInc; . |
GO | GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . |
GO | GO:0004127; F:cytidylate kinase activity; IEA:EC; . |
GO | GO:0016776; F:phosphotransferase activity; phosphate group as acceptor; IEA:InterPro |
GO | GO:0004849; F:uridine kinase activity; TAS:ProtInc; . |
GO | GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome; . |
InterPro | IPR000850; Adenylate_kin; . |
InterPro | IPR006266; UMP_CMP_kinase; . |
PANTHER | PTHR23359; Adenylate_kin; 1; . |
Pfam | PF00406; ADK; 1; . |
PRINTS | PR00094; ADENYLTKNASE; . |
TIGRFAMs | TIGR01359; UMP_CMP_kin_fam; 1; . |
PROSITE | PS00113; ADENYLATE_KINASE; 1; . |