World-2DPAGE Home
Home  |  Contact
Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am CEST. Apologies for the inconvenience.

Attention: World-2DPAGE is no longer maintained. Previously submitted data can still be queried at World-2DPAGE Repository.

SWISS-2DPAGE 
Search by  [accession number] *
[description, ID or gene] 
[author names] 
[spot ID / serial number] 
[identification methods] 
[pI / Mw range] 
[combined fields] 
Maps  [experimental info] 
[protein list] 
[graphical interface]
     Select Remote Interfaces
[All Interfaces]
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
has only effect if a remote
interface is selected
     

Sample Preparation and Post-separation Analysis


Searching in 'SWISS-2DPAGE' for entry matching: O00488




SWISS-2DPAGE:  O00488

O00488


General information about the entry
View entry in simple text format
Entry nameZN593_HUMAN
Primary accession numberO00488
integrated into SWISS-2DPAGE on November 9, 2001 (release 15)
2D Annotations were last modified onMarch 31, 2004 (version 1)
General Annotations were last modified on May 19, 2011 (version 8)
Name and origin of the protein
DescriptionRecName: Full=Zinc finger protein 593; AltName: Full=Zinc finger protein T86;.
Gene nameName=ZNF593
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, ExPASy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_2D_HUMAN {2D-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_2D_HUMAN
  map experimental info
  protein estimated location 		 
NUCLEOLI_HELA_2D_HUMAN

MAP LOCATIONS:
pI=5.58; Mw=19433

MAPPING (identification):
Peptide mass fingerprinting [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtO00488; ZN593_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameZN593_HUMAN
Primary accession numberO00488
Secondary accession number(s) B2R4S0 Q5T2H7
Sequence was last modified on July 28, 2009 (version 2)
Annotations were last modified on September 21, 2011 (version 96)
Name and origin of the protein
DescriptionRecName: Full=Zinc finger protein 593; AltName: Full=Zinc finger protein T86;
Gene nameName=ZNF593
Encoded onName=ZNF593
Keywords3D-structure; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAK311926; BAG34867.1; ALT_INIT; mRNA
EMBLAL391650; CAI17137.1; -; Genomic_DNA
EMBLCH471059; EAX07843.1; -; Genomic_DNA
EMBLBC002580; AAH02580.1; ALT_INIT; mRNA
EMBLBC019267; AAH19267.1; ALT_INIT; mRNA
EMBLD45213; BAA20369.1; ALT_INIT; mRNA
IPIIPI00844193; -; .
RefSeqNP_056955.2; NM_015871.4; .
UniGeneHs.477273; -; .
PDB1ZR9; NMR; -; A=20-134
PDBsum1ZR9; -; .
ProteinModelPortalO00488; -; .
SMRO00488; 46-112; .
IntActO00488; 1; .
MINTMINT-1387753; -; .
STRINGO00488; -; .
PhosphoSiteO00488; -; .
SWISS-2DPAGEO00488; -; .
PRIDEO00488; -; .
EnsemblENST00000374266; ENSP00000363384; ENSG00000142684; .
GeneID51042; -; .
KEGGhsa:51042; -; .
CTD51042; -; .
GeneCardsGC01P024750; -; .
HGNCHGNC:30943; ZNF593; .
neXtProtNX_O00488; -; .
PharmGKBPA134962156; -; .
eggNOGprNOG19318; -; .
GeneTreeENSGT00390000004173; -; .
HOVERGENHBG058255; -; .
OrthoDBEOG4ZS94N; -; .
PhylomeDBO00488; -; .
ArrayExpressO00488; -; .
BgeeO00488; -; .
CleanExHS_ZNF593; -; .
GenevestigatorO00488; -; .
GermOnlineENSG00000142684; Homo sapiens; .
GOGO:0005730; C:nucleolus; IEA:UniProtKB-SubCell; .
GOGO:0003677; F:DNA binding; IEA:UniProtKB-KW; .
GOGO:0003714; F:transcription corepressor activity; TAS:ProtInc; .
GOGO:0008270; F:zinc ion binding; IEA:InterPro; .
GOGO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc; .
GOGO:0006351; P:transcription; DNA-dependent; IEA:UniProtKB-KW
InterProIPR007087; Znf_C2H2; .
InterProIPR015880; Znf_C2H2-like; .
InterProIPR022755; Znf_C2H2_jaz; .
PfamPF12171; zf-C2H2_jaz; 1; .
SMARTSM00355; ZnF_C2H2; 1; .
PROSITEPS00028; ZINC_FINGER_C2H2_1; 1; .
PROSITEPS50157; ZINC_FINGER_C2H2_2; 1; .


SWISS-2DPAGE image

SWISS-2DPAGE (search AC)

Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server