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SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: O75691




SWISS-2DPAGE:  O75691


O75691


General information about the entry
View entry in simple text format
Entry nameUTP20_HUMAN
Primary accession numberO75691
integrated into SWISS-2DPAGE on May 15, 2003 (release 16)
2D Annotations were last modified onMay 15, 2003 (version 1)
General Annotations were last modified on May 19, 2011 (version 6)
Name and origin of the protein
DescriptionRecName: Full=Small subunit processome component 20 homolog; AltName: Full=Down-regulated in metastasis protein; AltName: Full=Novel nucleolar protein 73; Short=NNP73; AltName: Full=Protein Key-1A6;.
Gene nameName=UTP20
Synonyms=DRIM
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   MAPPING ON GEL
PubMed=12429849; [NCBI, Expasy, EBI, Israel, Japan]
Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.
''''''Functional proteomic analysis of human nucleolus'';'';''
Mol. Biol. Cell. 13(1):4100-4109(2002)
2D PAGE maps for identified proteins
How to interpret a protein

NUCLEOLI_HELA_1D_HUMAN {SDS-PAGE of nucleolar proteins from Human HeLa cells}
Homo sapiens (Human)
Tissue: Cervix carcinoma
NUCLEOLI_HELA_1D_HUMAN
  map experimental info
  protein estimated location
 
NUCLEOLI_HELA_1D_HUMAN

MAP LOCATIONS:
Mw=94000  [identification data]

MAPPING (identification):
Tandem mass spectrometry [1].

Copyright
This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
Cross-references
UniProtKB/Swiss-ProtO75691; UTP20_HUMAN.
2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 2011_10
Entry nameUTP20_HUMAN
Primary accession numberO75691
Secondary accession number(s) Q9H3H4
Sequence was last modified on May 18, 2010 (version 3)
Annotations were last modified on September 21, 2011 (version 86)
Name and origin of the protein
DescriptionRecName: Full=Small subunit processome component 20 homolog; AltName: Full=Down-regulated in metastasis protein; AltName: Full=Novel nucleolar protein 73; Short=NNP73; AltName: Full=Protein Key-1A6;
Gene nameName=UTP20
Synonyms=DRIM
Encoded onName=UTP20; Synonyms=DRIM
KeywordsCoiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; rRNA processing.
Copyright
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAJ006778; CAA07243.1; -; mRNA
EMBLAC063948; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAC063951; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAF072718; AAG35208.1; ALT_INIT; mRNA
IPIIPI00004970; -; .
RefSeqNP_055318.2; NM_014503.2; .
UniGeneHs.295732; -; .
ProteinModelPortalO75691; -; .
SMRO75691; 129-159; 1820-1877; 2108-2141
2254-2315.
IntActO75691; 2; .
MINTMINT-1163597; -; .
STRINGO75691; -; .
PhosphoSiteO75691; -; .
SWISS-2DPAGEO75691; -; .
PRIDEO75691; -; .
EnsemblENST00000261637; ENSP00000261637; ENSG00000120800; .
GeneID27340; -; .
KEGGhsa:27340; -; .
UCSCuc001tia.1; human; .
CTD27340; -; .
GeneCardsGC12P098734; -; .
H-InvDBHIX0010919; -; .
HGNCHGNC:17897; UTP20; .
MIM612822; gene; .
neXtProtNX_O75691; -; .
PharmGKBPA143485666; -; .
eggNOGprNOG15487; -; .
GeneTreeENSGT00390000016813; -; .
HOGENOMHBG357312; -; .
HOVERGENHBG094143; -; .
InParanoidO75691; -; .
OMASLQNYIM; -; .
OrthoDBEOG41C6VB; -; .
NextBio50408; -; .
ArrayExpressO75691; -; .
BgeeO75691; -; .
CleanExHS_UTP20; -; .
GenevestigatorO75691; -; .
GermOnlineENSG00000120800; Homo sapiens; .
GOGO:0030686; C:90S preribosome; ISS:UniProtKB; .
GOGO:0005737; C:cytoplasm; ISS:UniProtKB; .
GOGO:0005730; C:nucleolus; IDA:UniProtKB; .
GOGO:0005654; C:nucleoplasm; ISS:UniProtKB; .
GOGO:0030688; C:preribosome; small subunit precursor; ISS:UniProtKB
GOGO:0032040; C:small-subunit processome; ISS:UniProtKB; .
GOGO:0005515; F:protein binding; IPI:UniProtKB; .
GOGO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA; 5.8S rRNA; LSU-rRNA)
ISS:UniProtKB.
GOGO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA; 5.8S rRNA; LSU-rRNA)
ISS:UniProtKB.
GOGO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA; 5.8S rRNA; LSU-rRNA)
ISS:UniProtKB.
GOGO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc; .
InterProIPR016024; ARM-type_fold; .
InterProIPR011430; DRIM; .
PfamPF07539; DRIM; 1; .
SUPFAMSSF48371; ARM-type_fold; 2; .
PROSITEPS50077; HEAT_REPEAT; FALSE_NEG; .



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Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server