Attention: World-2DPAGE is no longer maintained.

Sample Preparation and Post-separation Analysis

P00751:

ID   CFAB_HUMAN; STANDARD; 2DG.
AC   P00751;
DT   01-AUG-1993, integrated into SWISS-2DPAGE (release 0).
DT   01-DEC-2000, 2D annotation version 1.
DT   19-MAY-2011, general annotation version 13.
DE   RecName: Full=Complement factor B; EC=3.4.21.47; AltName: Full=C3/C5
DE   convertase; AltName: Full=Glycine-rich beta glycoprotein; Short=GBG;
DE   AltName: Full=PBF2; AltName: Full=Properdin factor B; Contains: RecName:
DE   Full=Complement factor B Ba fragment; Contains: RecName: Full=Complement
DE   factor B Bb fragment; Flags: Precursor;.
GN   Name=CFB; Synonyms=BF, BFD;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Hominidae; Homo.
OX   NCBI_TaxID=9606;
MT   PLASMA_HUMAN.
IM   PLASMA_HUMAN.
RN   [1]
RP   MAPPING ON GEL.
RX   MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan]
RA   Anderson N.L., Anderson N.G.;
RT   ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'';
RL   Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977).
CC   -!- SUBUNIT: SINGLE CHAIN 
2D   -!- MASTER: PLASMA_HUMAN;
2D   -!-   PI/MW: SPOT 2D-0004BC=5.88/104346;
2D   -!-   PI/MW: SPOT 2D-0004BJ=5.97/102877;
2D   -!-   PI/MW: SPOT 2D-0004BM=6.05/101428;
2D   -!-   PI/MW: SPOT 2D-0004BR=6.13/100000;
2D   -!-   PI/MW: SPOT 2D-0004C4=6.20/99240;
2D   -!-   PI/MW: SPOT 2D-0004C6=6.28/99240;
2D   -!-   NORMAL LEVEL: 100-400 MG/L [1].
2D   -!-   PATHOLOGICAL LEVEL: DECREASED DURING LUPUS ERYTHEMATOSUS,
2D         INFECTIONS WITH GRAM- BACTERIA, IMMUNOCOMPLEX NEPHRITIS, DISSAMINATED
2D         INTRAVASCULAR COAGULATION, RHEUMATOID ARTHRITIS AND MEMBRANOPROLIFERATIVE
2D         GLOMERULONEPHRITIS [1]; INCREASED DURING ACUTE INFLAMMATIONS [1].
2D   -!-   POSITIONAL VARIANTS: GBFF, GBFS AND GBSS VARIANTS [1].
2D   -!-   MAPPING: IMMUNOBLOTTING [1].
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DR   DOSAC-COBS 2D-PAGE; P00751; P00751.
DR   DOSAC-COBS-2DPAGE; P00751; CFAB_HUMAN.
DR   REPRODUCTION-2DPAGE; P00751; P00751.
DR   Siena-2DPAGE; P00751; CFAB_HUMAN.
DR   UniProtKB/Swiss-Prot; P00751; CFAB_HUMAN.
//

The following 2-D map is available for this protein:

	Plasma

SWISS-2DPAGE (search AC)