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SWISS-2DPAGE

Attention: World-2DPAGE is no longer maintained.
It will be discontinued on 31-May-2024.

Swiss-2DPAGE data (text records and image files) will continue to be available from https://ftp.expasy.org/databases/swiss-2dpage/.


SWISS-2DPAGE 
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Sample Preparation and Post-separation Analysis



Searching in 'SWISS-2DPAGE' for entry matching: P02649




SWISS-2DPAGE: P02649



P02649:

Nice View - a user-friendly view of this entry
ID   APOE_HUMAN; STANDARD; 2DG.
AC   P02649;
DT   01-FEB-1995, integrated into SWISS-2DPAGE (release 1).
DT   01-DEC-2000, 2D annotation version 1.
DT   19-MAY-2011, general annotation version 12.
DE   RecName: Full=Apolipoprotein E; Short=Apo-E; Flags: Precursor;.
GN   Name=APOE;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Hominidae; Homo.
OX   NCBI_TaxID=9606;
MT   CSF_HUMAN, PLASMA_HUMAN.
IM   CSF_HUMAN, PLASMA_HUMAN.
RN   [1]
RP   MAPPING ON GEL.
RX   MEDLINE=78094420; PubMed=271964; [NCBI, Expasy, EBI, Israel, Japan]
RA   Anderson N.L., Anderson N.G.;
RT   ''''''High resolution two-dimensional electrophoresis of human plasma proteins'';'';'';
RL   Proc. Natl. Acad. Sci. U.S.A. 74(1):5421-5425(1977).
RN   [2]
RP   MAPPING ON GEL.
RX   MEDLINE=96007934; PubMed=7498157; [NCBI, Expasy, EBI, Israel, Japan]
RA   Sanchez J.-C., Appel R.D., Golaz O.G., Pasquali C., Ravier F., Bairoch
RA   A., Hochstrasser D.F.;
RT   ''''''Inside SWISS-2DPAGE database'';'';'';
RL   Electrophoresis 16(1):1131-1151(1995).
CC   -!- SUBUNIT: MONOMER 
2D   -!- MASTER: CSF_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000C5W=5.07/34489;
2D   -!-   PI/MW: SPOT 2D-000C6F=5.23/33314;
2D   -!-   PI/MW: SPOT 2D-000C6Q=5.34/32904;
2D   -!-   PI/MW: SPOT 2D-000C79=5.47/31940;
2D   -!-   AMINO ACID COMPOSITION: SPOT 2D-000C6F: A=12.03, B=4.12, F=1.03,
2D         G=5.84, H=0.69, I=0.69, K=4.12, L=12.71, M=2.41, P=2.75, R=11.68, S=4.81,
2D         T=3.78, V=7.56, Y=1.37, Z=24.40;
2D   -!-   MAPPING: MATCHING WITH THE PLASMA MASTER GEL [2].
2D   -!- MASTER: PLASMA_HUMAN;
2D   -!-   PI/MW: SPOT 2D-000573=5.24/35320;
2D   -!-   PI/MW: SPOT 2D-000578=5.35/34966;
2D   -!-   PI/MW: SPOT 2D-00057M=5.49/34200;
2D   -!-   NORMAL LEVEL: 30-50 MG/L.
2D   -!-   PATHOLOGICAL LEVEL: APOE ABNORMALITIES IN TYPE III AND IV HYPERLIPAEMIA.
2D   -!-   POSITIONAL VARIANTS: APOE 2-2, 2-3, 2-4, 3-3, 3-4 AND 4-4.
2D   -!-   MAPPING: IMMUNOBLOTTING [1].
CC   ---------------------------------------------------------------------------
CC   This SWISS-2DPAGE entry is copyright the Swiss Institute of Bioinformatics.
CC   There are no restrictions on its use by non-profit institutions as long as
CC   its content is in no way modified and this statement is not removed.
CC   Usage by and for commercial entities requires a license agreement (See
CC   http://world-2dpage.expasy.org/swiss-2dpage/docs/license.html or send email from legal@sib.swiss).
CC   ---------------------------------------------------------------------------
DR   DOSAC-COBS 2D-PAGE; P02649; P02649.
DR   DOSAC-COBS-2DPAGE; P02649; APOE_HUMAN.
DR   UniProtKB/Swiss-Prot; P02649; APOE_HUMAN.
//


The following 2-D maps are available for this protein:
Cerebrospinal Fluid
CSF_HUMAN
Plasma
PLASMA_HUMAN


SWISS-2DPAGE image

SWISS-2DPAGE (search AC)


Database constructed and maintained by SIB, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the Expasy web server